Abraxane 100mg (Injection)

Manufacturer: Biocon

Salt Composition : Paclitaxel(100mg)

Prescription
Prescription Required: Consult the Doctor & Get Your ePrescription

Some common side effects of this medicine include nausea, vomiting, and weakness. It may also cause serious side effects such as swelling of hands, lips, hair loss, and weight gain. To reduce these side effects your doctor may suggest some medication along with it. But, inform your doctor if you notice unexplained bruising or bleeding, sore throat, mouth ulcers, high temperature (fever). This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells and liver function.


Basic Information

Mechanism Of Action

Abraxane is a microtubule inhibitor that promotes the assembly of microtubules from tubulin dimers and stabilizes microtubules by preventing depolymerization.

Pharmacokinets

Paclitaxel is a new anticancer agent showing significant promise as therapy for solid tumours and leukaemia, given alone or in combination with other chemotherapeutic agents. Paclitaxel concentrations in biological specimens can be measured using high performance liquid chromatography, or more recently by immunoassay.

Side Effects

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Abraxane

Nausea

Vomiting

Weakness

Low blood platelets

Rash

Upper respiratory tract infection

Urinary tract infection

Bleeding

Anemia (low number of red blood cells)

Flushing (sense of warmth in the face, ears, neck and trunk)

Hair loss

Decreased blood pressure

Peripheral neuropathy (tingling and numbness of feet and hand)

Diarrhea

Decreased white blood cell count (neutrophils)

Contra Indications

Hypersensitivity to paclitaxel or castor oil.

Solid tumor w/baseline PMN less than 1500 cells/m³

AIDS-related Kaposi's sarcoma with baseline PMN less than 1000 cells/m³

Pregnancy Related Information

Abraxane 100mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Product And Alcohol Interaction

It is unsafe to consume alcohol with Abraxane 100mg Injection.

Breast Feeding Related Information

Abraxane 100mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Indications

Abraxane 100mg Injection helps to treat breast cancer and it may be used alone or in combination with other medicines or treatment modalities like chemotherapy. It relieves the symptoms of breast cancer such as breast lumps, bloody discharge from nipples or changes in the shape or texture of the breast.

Interactions

Paclitaxel has no known severe interactions with other drugs.

Serious interactions of paclitaxel include:

adenovirus types 4 and 7 live, oral.

eluxadoline.

idarubicin.

idelalisib.

influenza virus vaccine trivalent, adjuvanted.

ivacaftor.

nefazodone.

palifermin.

Typical Dosage

Kindly do not self administer.

Storage Requirements

Store below 30°C

Expert Advice

Abraxane 100mg Injection is an anti-cancer medication used for the treatment of breast cancer, pancreatic cancer, and non-small cell lung cancer.

It is given as an intravenous (IV) injection into your vein, usually over 1 hour and every three weeks.

Do not take Abraxane 100mg Injection if you are pregnant or breastfeeding. Use reliable methods of contraception to prevent pregnancy while taking this medicine.

Your doctor may get regular blood tests done to monitor your blood cells and liver function during treatment with this medicine.

Inform your doctor if you notice unexplained bruising or bleeding, sore throat, mouth ulcers, high temperature (fever) or other signs of infection.

Talk to your doctor if you have sudden weight gain or if you have swelling in your arms and legs that doesn't go away.

How To Use

Your doctor or nurse will give you this medicine. Kindly do not self administer.

FAQs

Q. Is Abraxane 100mg Injection generic/ taxane/ FDA approved/cytotoxic?

Yes, Abraxane 100mg Injection is generic/ taxane/ FDA approved/ cytotoxic

Q. Is Abraxane 100mg Injection a vesicant?

Abraxane 100mg Injection is usually a vesicant (irritant)

Q. Is Abraxane 100mg Injection light sensitive/ hydrophobic/ cardiotoxic?

Yes, Abraxane 100mg Injection is light sensitive/ hydrophobic/ cardiotoxic

Q. Does Abraxane 100mg Injection cause hair loss?

Yes, Abraxane 100mg Injection may cause hair loss as a side effect. Please inform your doctor about any side effect while you are on Abraxane 100mg Injection therapy

Q. What is Abraxane 100mg Injection derived from?

Abraxane 100mg Injection is derived from bark of the Pacific yew, Taxus brevifolia.