Manufacturer: Emcure Pharmaceuticals Ltd
Salt Composition : Gabapentin(400mg), Nortriptyline(10mg)
Acegaba NT 400mg/10mg Tablet is taken by mouth, with or without food and preferably at night. It is advised to take it at a fixed time each day to maintain a consistent level of medicine in the blood. In case you miss a dose of this medicine, take it as soon as you remember. Finish the full course of treatment even if you feel better. It is important not to stop taking this medicine suddenly without talking to the doctor as it may worsen your symptoms.
Acegaba-NT 400 Tablet 15's belongs to a combination medicine of anticonvulsant (Gabapentin) and antidepressant (Nortriptyline) used for the management of neuropathic pain. It is a chronic progressive nerve disease that causes nerve pain.
Pharmacokinetics. Gabapentin is absorbed from the intestines by an active transport process mediated via an amino acid transporter, presumably, LAT2. As a result, the pharmacokinetics of gabapentin is dose-dependent, with diminished bioavailability and delayed peak levels at higher doses.
The pharmacokinetics of TCAs are reviewed with particular emphasis on nortriptyline, the agent most extensively studied. The clinical uses of TCA plasma level-response studies are discussed in relationship to rational dosage adjustment to increase response rates and avoid iatrogenic toxicity.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Acegaba NT
Constipation
Difficulty in urination
Weight gain
Sleepiness
Dizziness
Tiredness
Blurred vision
Dryness in mouth
Orthostatic hypotension (sudden lowering of blood pressure on standing)
Increased heart rate
Uncoordinated body movements
If you are allergic to gabapentin, nortriptyline or any of the other ingredients of Acegaba-NT 400 Tablet..
If you are taking certain medicines (MAO Inhibitors) for some psychiatric disorders.
Acegaba NT 400mg/10mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Acegaba NT 400mg/10mg Tablet may cause excessive drowsiness with alcohol.
Acegaba NT 400mg/10mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Acegaba-NT 400 Tablet is a combination medicine used to treat long-lasting (chronic) pain caused by nerve damage due to diabetes, shingles or spinal cord injury. It reduces pain and its associated symptoms such as mood changes, sleep problems, and tiredness.
DRUG-DRUG INTERACTIONS: Acegaba-NT 400 Tablet may have interaction with hypnotics (zolpidem), antidepressants (citalopram, duloxetine, escitalopram, fluoxetine, bupropion, sertraline), pain killer (codeine, hydrocodone, acetaminophen, oxycodone, tramadol, methadone), anti-histamine (diphenhydramine, cetirizine).
Do not chew, crush or break it. Acegaba NT 400mg/10mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Store below 30°C
If you miss a dose of Acegaba NT 400mg/10mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Acegaba NT 400mg/10mg Tablet is used to treat certain types of long-lasting pain caused by damage to nerves.
Inform your doctor if you are taking any other pain-relieving medicines.
Along with taking this medicine, your doctor might advise you to undergo physiotherapy to get relief from pain.
Avoid taking antacids 2 hours before or after taking Acegaba NT 400mg/10mg Tablet as they make it harder for your body to absorb the medicine.
Acegaba NT 400mg/10mg Tablet is used to treat certain types of long-lasting pain caused by damage to nerves.
Inform your doctor if you are taking any other pain-relieving medicines.
Along with taking this medicine, your doctor might advise you to undergo physiotherapy to get relief from pain.
Avoid taking antacids 2 hours before or after taking Acegaba NT 400mg/10mg Tablet as they make it harder for your body to absorb the medicine.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Acegaba NT 400mg/10mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Q. What is Acegaba NT 400mg/10mg Tablet?
Acegaba NT 400mg/10mg Tablet is a combination of two medicines: Gabapentin and Nortriptyline. This medicine is useful in the treatment of nerve pain (Neuropathic pain). It calms the damaged or overactive nerves by acting on the brain. Thereby, it decreases the pain sensation.
Q. Can I stop taking Acegaba NT 400mg/10mg Tablet when my pain is relieved?
No, you should not stop taking $nmae even if your pain is relieved. Continue to take it as advised by your doctor. If you suddenly stop taking Acegaba NT 400mg/10mg Tablet, you may experience withdrawal symptoms such as anxiety, sleeping difficulties, nausea, pain and sweating. You may need to gradually taper the dose before you stop the medication completely.
Q. How to manage weight gain associated with the use of Acegaba NT 400mg/10mg Tablet?
Acegaba NT 400mg/10mg Tablet can make you feel hungry which might make you eat more, thereby increasing your chances of putting on weight. However, preventing weight gain is easier than losing the increased weight. Try to eat a healthy balanced diet without increasing your portion sizes (per-meal intake). Do not eat food items that contain a lot of calories, such as soft drinks, oily food, chips, cakes, biscuits, and sweets. If you feel hungry between meals avoid eating junk food and eat fruits, vegetables and low-calorie foods. Regular exercise will help prevent weight gain. If you maintain good eating habits and exercise regularly, you might not gain any weight.
Q. Can the use of Acegaba NT 400mg/10mg Tablet affect my sexual life?
The use of Acegaba NT 400mg/10mg Tablet can affect the sexual life of both men and women. Most commonly observed problems are decreased sexual desire, erectile dysfunction (inability to develop or maintain erection during the sexual activity) and inability to reach orgasm. It can also cause a decrease in satisfaction and cause discomfort while intercourse. If you experience these problems, discuss them with your doctor but do not stop taking Acegaba NT 400mg/10mg Tablet.
Q. Are there any serious side effects associated with the use of Acegaba NT 400mg/10mg Tablet?
Serious side effects because of Acegaba NT 400mg/10mg Tablet are uncommon and rare. Consult your doctor immediately if you notice any of the following: changes in body temperature, difficulty in breathing, increased heartbeat (palpitations), weakness, unsteadiness when walking, reduced coordination or slowed reactions, unusual changes in mood or behavior (such as restlessness, nervousness or excitement), signs of depression, seeing or hearing things that are not there, irrational thinking, blurred or double vision, uncontrollable jerky eye movements, difficulty seeing, signs of frequent infections such as fever, severe chills, sore throat or mouth ulcers. These side effects are uncommon but may be serious and need urgent medical attention.
Q. How long will the Acegaba NT 400mg/10mg Tablet take to act?
An initial benefit with Acegaba NT 400mg/10mg Tablet may be seen after 2 weeks of treatment. However, it may take around 2-3 months to see full benefit. It may even take longer in some patients.
Q. What if I forget to take Acegaba NT 400mg/10mg Tablet?
If you forget to take the scheduled dose of Acegaba NT 400mg/10mg Tablet and it is almost time for your next dose, skip the dose you missed and take your next dose at the scheduled time. Otherwise, take it as soon as you remember, and then go back to taking your medicine as you would normally. Do not take a double dose to make up for the dose you missed because this may increase the risk of unwanted side effect due to overdosage. If you are not sure what to do, ask your doctor about taking Acegaba NT 400mg/10mg Tablet.
Q. What if I take too much of this drug by mistake?
In a situation like this, contact your doctor immediately or seek emergency help at the nearest hospital. Do this even if there are no signs of discomfort or poisoning. You may need urgent medical attention. Overdose of this medicine may make you feel drowsy, weak, unsteady when walking, have double visions, slurred speech or diarrhea, confusion, blurred vision, dizziness, body temperature changes (low and high), difficulty in breathing and increased heartbeat.
Q. Is there anything I need to avoid while taking Acegaba NT 400mg/10mg Tablet?
Acegaba NT 400mg/10mg Tablet may impair your thinking or reactions. Be careful while driving or while doing any activity that requires you to be alert. Do not drink alcohol while you are taking Acegaba NT 400mg/10mg Tablet. It can increase the effects of alcohol which could be dangerous. Grapefruit and grapefruit juice may also interact with this medicine and cause unwanted side effects. Avoid exposure to sunlight or tanning beds. Use of Acegaba NT 400mg/10mg Tablet can make you more prone to sunburns. Wear protective clothing and use sunscreen when you are outdoors during daytime.
Q. How often should I see the doctor?
You may need to see your doctor regularly if you have started to take Acegaba NT 400mg/10mg Tablet. However, you must consult your doctor if the advised dosage of Acegaba NT 400mg/10mg Tablet does not improve your symptoms or you continue experiencing unwanted side effects that affect your routine activities.
Q. Can the use of Acegaba NT 400mg/10mg Tablet cause sleepiness or drowsiness?
Yes, Acegaba NT 400mg/10mg Tablet may make you feel drowsy or may cause you to suddenly fall asleep during your daily activities. You might not even feel drowsy or have any other warning signs before you suddenly fall asleep. Avoid driving a car, operating machinery, working at heights or participating in potentially dangerous activities at the beginning of your treatment until you know how the medication affects you. Inform your doctor if you experience such episodes while you are taking this medicine.
Q. Will Acegaba NT 400mg/10mg Tablet be more effective if taken more than recommended dose?
No, taking a higher than the recommended dose may not be more effective, rather it may increase the chances of having some serious side effects and toxicity. If you experience increased severity of your symptoms that are not relieved by the recommended doses, please consult your doctor for re-evaluation.
Q. What are the storage condition for Acegaba NT 400mg/10mg Tablet?
Keep your tablets in the pack until it is time to take them. Store them in a cool dry place. Store them out of sight and out of reach of children. Unused medications should be disposed of in special ways to ensure that pets, children and other people cannot consume them.
