Acinostop 2gm (Injection)

Manufacturer: Glenmark Pharmaceuticals Ltd

Salt Composition : Sulbactam(2gm)


Acinostop 1gm Injection is used in combination with other antibiotics for the treatment of various types of serious bacterial infections such as pneumonia, skin and soft tissue infections, urinary tract infections, and others.


Acinostop 1gm Injection is a type of antibiotic belonging to a class known as beta-lactamase inhibitors. This medicine helps to make the bacteria more sensitive to antibiotic activity. It is given by drip (intravenous infusion) or by direct injection into a vein, under the supervision of a healthcare professional. It should be used regularly at evenly spaced intervals, as per the schedule prescribed by your doctor.


Do not skip any doses and finish the full course of treatment even if you feel better. Stopping the medicine too early may lead to the infection returning or worsening. The total duration of treatment and precise dosage will be decided by your doctor, depending on the type of infection that you have and how well you respond to the medication.


Before taking this medicine, inform your doctor if you have a history of an allergic reaction to this medicine or penicillin group of medicines. Diarrhea and local pain, swelling, or redness at the site of injection may be seen as side effects in some patients. These are temporary and usually resolve quickly. Consult your doctor if any of these side effects persist or if your condition worsens. This medicine is generally regarded as safe to use during pregnancy if used under a doctor’s supervision.



Basic Information

Mechanism Of Action

Sulbactam is an irreversible inhibitor of β-lactamase; by binding and inhibiting β-lactamase produced by bacterial cells, sulbactam is thereby able to prevent it from reducing antibiotic activity

Pharmacokinets

Sulbactam is an beta-lactamase inhibitor antibiotic combined with other antibiotics to treat a variety of susceptible bacterial infections. Sulbactam is a β-lactamase inhibitor given in combination with β-lactam antibiotics to inhibit β-lactamase, an enzyme produced by bacteria that destroys antibiotic activity

Side Effects

Injection site pain

Diarrhea

Contra Indications

The use of UNASYN is contraindicated in individuals with a history of serious hypersensitivity reactions (e.g., anaphylaxis or Stevens-Johnson syndrome) to ampicillin, sulbactam or to other beta-lactam antibacterial drugs

Pregnancy Related Information

Acinostop 1gm Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.


Product And Alcohol Interaction

Consuming alcohol with Acinostop 1gm Injection does not cause any harmful side effects.


Breast Feeding Related Information

Acinostop 1gm Injection is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.


Indications

Gynecologic Infections. ...

Intra-Abdominal Infections. ...

Skin & Skin Structure Infections. ...

Orbital Cellulitis. ...

Pelvic Inflammatory Disease. ...

Pneumonia. ...

Urinary Tract Infections. ...

Acute Bacterial Rhinosinusitis

Interactions

Some products that may interact with this drug include: aminoglycosides (such as gentamicin), "blood thinners" (such as warfarin), methotrexate, tetracyclines. This medication may interfere with certain laboratory tests (including certain urine glucose tests), possibly causing false test results

Typical Dosage

 Kindly do not self administer.


Storage Requirements

Store below 30°C


Effects Of Missed Dosage

If you miss a dose of Acinostop 1gm Injection, consult your doctor.


Effects Of Overdose

Consult a doctor before taking any medicines.


Expert Advice

Acinostop 1gm Injection is used in treatment of severe bacterial infections, in combination with certain antibiotics.

It is also used alone in the treatment of serious infections caused by pathogen Acinetobacter baumannii including those resistant to other antibiotics.

It is preferentially given as an injection directly into a vein over a period of 15-60 minutes.

When used alone, it is associated with few adverse effects, mainly pain at the injection site and diarrhea.

How To Use

Your doctor or nurse will give you this medicine. Kindly do not self administer.


FAQs

Q. Why is Acinostop 1gm Injection added to other antibiotics?

Acinostop 1gm Injection added to other antibiotics like ampicillin, cefoperazone, etc., because Acinostop 1gm Injection contains Sulbactam, a beta-lactamase inhibitor, which reduces resistance and enhances the activity of other antibiotics like ampicillin, cefoperazone, etc., against the bacteria.

Q. Who should not take Acinostop 1gm Injection?

Acinostop 1gm Injection should not be taken by an individual if he/she had an allergic reaction to ampicillin, sulbactam, or any penicillin antibiotic (such as penicillins or cephalosporins), or if he/she has a history of liver problems caused by ampicillin/sulbactam.

Q. What should I discuss with my doctor before receiving Acinostop 1gm Injection?

Before taking Acinostop 1gm Injection, you should tell your doctor if you have ever had an allergic reaction to Acinostop 1gm Injection or any similar medicine. Inform the doctor if you have any type of allergy, asthma or breathing problems, heart disease or kidney disease. Let your doctor know about all the medicines that you may be taking as they may affect or be affected by Acinostop 1gm Injection. Pregnant or breastfeeding mothers should also seek their doctor’s advice before taking Acinostop 1gm Injection.

Q. Can I use a discolored solution of Acinostop 1gm Injection?

No. You should not use Acinostop 1gm Injection if the medicine has changed colors or has particles in it. The discolored solution may be contaminated and may not be as effective as it is expected to be. Also, it may cause additional side effects. So, it is better, that you discard the solution and go for another vial.