Manufacturer: Windlas Biotech Ltd
Salt Composition : Domperidone(10mg), Rabeprazole(20mg)
Strip of 10 Tablet
(Inclusive of all taxes)
Aciraze D 10 mg/20 mg Tablet is taken without food in a dose and duration as advised by the doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your healthcare team know about all other medications you are taking as some may affect, or be affected by this medicine.
Aciraze D 10 mg/20 mg Tablet is a combination medicine used to treat gastroesophageal reflux disease (Acid reflux) and peptic ulcer disease by relieving the symptoms of acidity such as heartburn, stomach pain, or irritation. It also neutralizes the acid and promotes easy passage of gas to reduce stomach discomfort.
The absolute bioavailability of domperidone is low (13–17% or approximately 15%). This is due to extensive first-pass metabolism in the intestines and liver. Conversely, its bioavailability is high via intramuscular injection (90%). The onset of action of domperidone taken orally is about 30 to 60 minutes.
The pharmacokinetics of rabeprazole are characterized by high and consistent bioavailability, dose proportionality, extensive hepatic metabolism, and primarily urinary excretion of these metabolites. In addition, rabeprazole does not accumulate with repeated dosing.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Aciraze D
Diarrhea
Stomach pain
Dryness in mouth
Headache
Dizziness
Flatulence
Weakness
Flu-like symptoms
with conditions where cardiac conduction is, or could be, impaired.
with underlying cardiac diseases such as congestive heart failure.
receiving other medications known to prolong QT interval or potent CYP3A4 inhibitors.
with severe hepatic impairment.
Aciraze D 10 mg/20 mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Caution is advised when consuming alcohol with Aciraze D 10 mg/20 mg Tablet. Please consult your doctor.
Aciraze D 10 mg/20 mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
It treats symptoms of acid reflux due to hyperacidity, stomach ulcer (Peptic ulcer disease), and Zollinger Ellison syndrome (overproduction of acid due to a pancreatic tumour). Besides this which is used short-term to treat symptoms of gastroesophageal reflux disease (GERD).
Drug-Drug Interaction: DOMPERIDONE+RABEPRAZOLE may interact with a blood thinner (clopidogrel, warfarin), antifungal (ketoconazole, voriconazole, itraconazole, fluconazole, posaconazole), anti-HIV drug (atazanavir, amprenavir, nelfinavir), antacid (magnesium hydroxide, aluminium hydroxide, cimetidine), iron supplements
Do not chew, crush or break it. Aciraze D 10 mg/20 mg Tablet is to be taken empty stomach.
Store below 30°C
If you miss a dose of Aciraze D 10 mg/20 mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
You have been prescribed Aciraze D 10 mg/20 mg Tablet for the treatment of acidity and heartburn.
Take it one hour before the meal, preferably in the morning.
It is a well-tolerated medicine and provides relief for a long time.
Inform your doctor if you get watery diarrhea, fever or stomach pain that does not go away.
Inform your doctor if you do not feel better after taking it for 14 days as you may be suffering from some other problem that needs attention.
Long-term use can cause weak bones and deficiency of minerals such as magnesium. Take adequate dietary intake of calcium and magnesium or their supplements as prescribed by your doctor.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Aciraze D 10 mg/20 mg Tablet is to be taken empty stomach.
Q. What is Aciraze D 10 mg/20 mg Tablet?
Aciraze D 10 mg/20 mg Tablet is a combination of two medicines: Domperidone and Rabeprazole. This combination is used to treat acidity and heartburn or gastroesophageal reflux disease (GERD); a condition where the acid in the stomach flows back up into the food pipe (esophagus). It is also used to treat gastric and duodenal ulcers. Domperidone helps to control vomiting by increasing the movement of the gut, allowing the food to move more easily through the stomach.
Q. What are the contraindications of Aciraze D 10 mg/20 mg Tablet?
The use of Aciraze D 10 mg/20 mg Tablet is considered to be harmful for patients with a known hypersensitivity to rabeprazole or domperidone or any other inactive ingredients of the medicine. Caution is advised in patients with underlying kidney or liver disease.
Q. Can the use of Aciraze D 10 mg/20 mg Tablet cause dry mouth?
Yes, the use of Aciraze D 10 mg/20 mg Tablet can cause dry mouth. Dryness of mouth occurs due to Domperidone. If you experience dry mouth, drink plenty of water. Keep some water on your bedside at night. Cut down the intake of alcohol and avoid smoking. If you have dry mouth, try to use alcohol-free mouthwash as its use can increase the risk of tooth decay.
Q. Can the use of Aciraze D 10 mg/20 mg Tablet cause diarrhea?
Yes, the use of Aciraze D 10 mg/20 mg Tablet can cause diarrhea. In case you experience diarrhea, drink plenty of water or other fluids. Avoid taking fatty or fried foods along with this medication. Talk to your doctor if diarrhea persists and if you notice any signs of dehydration, like less urination with dark colored and strong-smelling urine.
Q. What is the recommended storage condition for Aciraze D 10 mg/20 mg Tablet?
Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
Q. Is it safe to use Aciraze D 10 mg/20 mg Tablet?
Yes, Aciraze D 10 mg/20 mg Tablet is safe for most of the patients. However, in some patients it may cause common side effects like diarrhea, stomach pain, flatulence, dryness in mouth, dizziness, headache and other uncommon and rare side effects. Inform your doctor if you experience any persistent problem while taking this medicine.
Q. What is the best time to take Aciraze D 10 mg/20 mg Tablet?
It is best to take Aciraze D 10 mg/20 mg Tablet before the first meal of the day or on an empty stomach.
Q. Can the use of Aciraze D 10 mg/20 mg Tablet cause abnormal heartbeat?
Yes, the use of Aciraze D 10 mg/20 mg Tablet can increase the risk of developing irregular heartbeat (serious arrhythmias). This is a serious side effect but the chance that it may happen is very low. The risk may be slightly higher in those who are more than 60 years of age.
