Manufacturer: Cipla Ltd
Salt Composition : Dapsone(5% w/w), Adapalene(0.1% w/w)
Acnedap Plus Gel is only meant for external use and should be used as advised by your doctor. A thin layer of the medicine should be applied only to the affected areas of the skin with clean and dry hands. Wash your hands before and after applying the medicine. If it gets into your eyes, nose, mouth, or vagina rinse with water. It may take several days to weeks for your symptoms to improve, but you should keep using this medicine regularly. The course of the treatment should be completed to ensure better efficacy of the medicine. If your condition does not improve or gets worse, you should talk to your doctor.
Acnedap Plus gel works by the combined action of both its components: Adapalene and Dapsone. Adapalene works by decreasing the swelling, redness of the skin, thus reducing pimples. Benzoyl Peroxide works by killing the bacteria that cause acne (or pimple).
The elimination half-life of dapsone is about 30 hours. The drug shows linear pharmacokinetics within the therapeutic range and the time-course after oral administration fits a 2-compartment model. The concentration-time profile of dapsone after parenteral administration is reviewed.
Pharmacokinetics: Absorption of adapalene from DIFFERIN Gel, 0.3% through human skin is low. In a pharmacokinetics study, 16 acne patients were treated once daily for 10 days with 2 grams of DIFFERIN Gel, 0.3% applied to the face, chest and back, corresponding to approximately 2 mg/cm2.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Acnedap Plus
Skin irritation
Itching
Burning sensation at the site of application
Erythema (skin redness)
Dryness
Avoid eyes, lips, and mucous membranes.
For external use only.
Minimize UV light exposure; use sunscreen and protective clothing.
Extreme weather (e.g., wind, cold) may cause skin irritation.
Adverse reaction risk higher during first month of treatment; generally subsides with use.
Acnedap Plus Gel may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
No interaction found/established
Acnedap Plus Gel is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Acnedap Gel 15 gm contains Dapsone used to treat acne (pimples). Acnedap Gel 15 gm inhibits the production of folic acid (vitamin) necessary for bacteria to grow, multiply and increase in numbers. Thereby, it stops or slows down the growth of bacteria causing acne and heals the skin by reducing swelling and redness.
Drug-Drug Interaction: ADAPALENE+DAPSONE may interact with vitamin A-related drugs known as retinoids (isotretinoin), photosensitizing agents (aminolevulinic acid, methoxsalen, porfirmer, verteporfin), sensitizer (methyl aminolevulinate), a local anaesthetic (prilocaine), keratolytic agents (benzoyl peroxide, salicylic.
Check the label for directions before use. Clean and dry the affected area and apply the gel.
Store below 30°C
Acnedap Plus Gel must be applied as a thin layer on the affected area as prescribed by your doctor.
Do not use this medicine more often or for longer than advised by your doctor.
Before each application, wash the affected area with soap and water and dry well.
Avoid getting it in the eyes, mouth or nose. Rinse with cold water if you accidentally get it in these areas.
It makes your skin sensitive towards sunlight. Use a sunscreen or wear protective clothing while going out.
It is advisable to avoid any kind of facial waxing or cosmetic procedure during acne treatment.
This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the gel. Wash your hands after applying, unless hands are the affected area.
