Manufacturer: Zydus Cadila
Salt Composition : Ursodeoxycholic Acid(600mg)
Actibile 600 SR Tablet should be swallowed whole after a meal and with a glass of milk or water. The dose will depend on what you are being treated for and your body weight. Take it regularly to get maximum benefit and keep taking it for as long as prescribed (several months or longer). Keep taking it even if your symptoms disappear.
This medicine's most common side effects are abdominal pain, diarrhea, hair loss, itching, nausea, and rash. Not everyone gets these side effects. If you are worried about them, or they do not go away, let your doctor know.
Before taking this medicine, you should tell your doctor if you have an inflammation of the gallbladder or bile ducts, you get frequent cramp-like pain in your upper abdomen, you have been coughing up blood or you have gained weight rapidly. Using this medicine can reduce or increase the effect of some other medicines so tell your doctor all other medicines you are taking. Women should discontinue hormonal birth control pills as they can increase the production of gallstones. During the treatment, you may need ultrasound scans, or frequent blood tests to check your liver function.
1. Headache 2. Abdominal pain 3. Dry mouth 4. Fatigue 5. Pharyngitis 6. Sleepiness 7. Asthenia 8. Rhinitis causing a blocked or runny nose 9. Migraine
1. Hypersensitivity to the drug 2. Renal impairment 3. Hepatic impairment 4. Diabetic ketoacidosis 5. Cardiovascular collapse 6. Hypotensive states 7. Respiratory disease 8. Alcoholics.
Contraindicated
1.Hepatic impairment 2.Renal impairment 3.Women of childbearing age should be cautioned against becoming pregnant while on Albendazole or within 1 month of completing treatment, 4.Perform liver function tests and blood counts during prolonged therapy.
Consuming alcohol with Axotum 1000mg/125mg Injection does not cause any harmful side effects.
Use with caution
Contraindicated
Use with caution Below 9years: Contraindicated
Actibile 600 SR Tablet is used to dissolve certain gallstones and prevent them from forming. It is also used to treat a type of liver disease called primary biliary cirrhosis. It helps break down the cholesterol that has converted into stones in your gallbladder thereby dissolving the stones
Actibile 600 SR Tablet is a medicine that helps decreases the amount of cholesterol produced by your liver. It helps to break down cholesterol that has formed into “stones” in the gallbladder. It may take several months to completely dissolve the stone, so you need to take the medicine regularly and as long as the doctor has prescribed it for it to be effective. There might be other medicines and certain lifestyle changes that can reduce your cholesterol level and make gallstones less likely, consult with your doctor
5 mg once daily. Maximum dose: 10mg/day Prinzmetal`s angina and Stable angina: 5 to 10mg once daily. Hypertension: 2.5 to 5mg once daily. Dose may increase up to 10mg once daily as required by the individual needs. .
Store at room temperature below 30 degree C. Protect from moisture and light.
If you miss a dose of Actibile 600 SR Tablet, skip it and continue with your normal schedule. Do not double the dose.
Never take more than the dose prescribed by your doctor. If you suspect an overdose of Actibile 600 MG Tablet, contact your doctor immediately for further guidance.
Actibile 600 SR Tablet should be taken after a meal with a glass of milk or water.
Eat a healthy diet, exercise regularly, and avoid alcohol intake.
Diarrhea may occur as a side effect. Drink plenty of fluids and inform your doctor if diarrhea persists or if you find blood in your stools.
Your doctor may monitor your liver function and bilirubin levels every month for the next 3 months after the start of therapy, and every 6 months thereafter. Do not stop taking the medication without talking to your doctor.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Actibile 600 SR Tablet is to be taken with food.
Q. When should I take Actibile 600 SR Tablet?
The suitable timing of taking this medicine might differ depending upon your condition. Your doctor might instruct you to take 2 to 3 doses per day and suggest to take the last dose at bedtime. Actibile 600 SR Tablet should be taken with water milk and can be taken with food or after food. When prescribed for dissolving gallstones, it is usually suggested to be taken once daily at night. Ideally, it should be taken at a gap of 6 hours, for example at 8 am, 2 pm and 8 pm.
Q. Is Actibile 600 SR Tablet safe?
Actibile 600 SR Tablet is usually considered to be a safe and effective medicine. However, this medicine may have some common side effects, such as diarrhea. If diarrhea occurs, your doctor may reduce the dose and if it persists, your treatment may be discontinued. Additionally, using this medicine as a long-term therapy may also affect your liver enzyme levels. To keep a check on this, your doctor will keep monitoring your liver enzyme levels regularly. Despite these minor side effects, this medicine is supposed to be a good alternative to surgery in some patients with gallstones.
Q. How does Actibile 600 SR Tablet help the liver?
Actibile 600 SR Tablet acts on the liver and gets concentrated in the bile secreted from the liver. This, as a result, suppresses the synthesis and secretion of cholesterol by the liver, thereby decreasing the cholesterol levels in bile. This medicine also acts by stopping the intestines from absorbing the bile salts and cholesterol. So, the reduced cholesterol saturation in the bile from the liver leads to the gradual dissolving of cholesterol from gallstones, leading to a decrease in size and their eventual dissolution. It also reduces elevated liver enzyme levels by increasing the bile flow through the liver, hence protecting the liver cells.
Q. Does Actibile 600 SR Tablet cause weight gain?
Yes, there is a chance of weight gain with Actibile 600 SR Tablet, but it is not common. The use of Actibile 600 SR Tablet can cause weight gain when prescribed in patients with liver disease associated with chronic stasis of bile in small bile ducts of the liver. In such condition, bile cannot flow from the liver to the small intestine. Again, the chance of weight gain varies from person to person depending upon the disease, so consult your doctor if you experience weight gain.
Q. What should I avoid while taking Actibile 600 SR Tablet?
While taking Actibile 600 SR Tablet, avoid taking an antacid preparation without consulting your doctor, as they decrease the effectiveness of Actibile 600 SR Tablet. You should also avoid medicines like cholestyramine or colestipol as they affect the effectiveness of Actibile 600 SR Tablet. So, ask your doctor about the time gap that should be maintained between Actibile 600 SR Tablet and these medicines. Also, avoid taking oral contraceptives, estrogenic hormones and blood cholesterol-lowering agents such as clofibrate as they may increase the chances of developing gallstones and act opposite to the Actibile 600 SR Tablet.
