Manufacturer: Boehringer Ingelheim
Salt Composition : Alteplase(20mg)
Actilyse 20mg Injection is given directly into a vein by a doctor as soon as possible after the first signs of a heart attack, stroke, or pulmonary embolism are noticed. Your breathing, blood pressure, oxygen levels and other vital signs will be watched closely. You may be given another medicine to prevent the formation of new blood clots at the same time or after the treatment.
Actilyse 20mg Injection is a thrombolytic medication. It works by dissolving the harmful blood clots in the blood vessels. This restores the blood flow to the affected tissue, thereby preventing tissue death and improving outcomes.
Pharmacokinetics. Alteplase in acute myocardial infarction (AMI) patients is rapidly cleared from the plasma with an initial half-life of less than 5 minutes. There is no difference in the dominant initial plasma half-life between the 3-hour and accelerated regimens for AMI.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Actilyse
Bleeding
Nausea
Vomiting
Confusion
Intracranial hemorrhage.
Subarachnoid hemorrhage.
Internal bleeding.
Stroke within the last three months.
Intracranial or intraspinal surgery within the last three months.
Serious head trauma within the last three months.
Intracranial neoplasms, arteriovenous malformations, or aneurysms.
Actilyse 20mg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
It is not known whether it is safe to consume alcohol with Actilyse 20mg Injection. Please consult your doctor.
Actilyse 20mg Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Actilyse 20mg Injection is a medicine which dissolves the clots that have formed in blood vessels. It is used to treat stroke, heart attack, and pulmonary embolism (blood clots in the lungs).
Actilyse 20mg Injection is prescribed for:
Treatment of Heart attack.
Treatment of Ischemic stroke.
Treatment of Pulmonary embolism.
Ask your doctor before taking aspirin or ibuprofen (Motrin, Advil) shortly after you have received alteplase. These medications can increase your risk of bleeding. Avoid activities that may increase your risk of bleeding or injury.
Kindly do not self administer.
Store below 30°C
It should be given as soon as possible (within 12 hours) after the onset of a heart attack or within 4.5 hours of onset of stroke.
Let your doctor know immediately if you develop any nosebleeds, gum bleeding, black or tarry stools, or bruising.
Do not discontinue the medicines started after this injection as it may increase your chances of having another heart attack or stroke.
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Q. How is Actilyse 20mg Injection administered?
Actilyse 20mg Injection should be administered under the supervision of a trained healthcare professional or a doctor only and should not be self-administered. The dose will depend on the condition you are being treated for and will be decided by your doctor. Follow your doctor’s instructions carefully to get maximum benefit from Actilyse 20mg Injection.
Q. Is Actilyse 20mg Injection safe?
Actilyse 20mg Injection is safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any dose. Follow your doctor's instructions carefully and let your doctor know if any of the side effects bother you.
Q. Can the use of Actilyse 20mg Injection increase the risk of bleeding?
Yes, Actilyse 20mg Injection can increase the risk of bleeding. Always be careful while doing activities that may cause an injury or bleeding. Tell your doctor immediately if you notice any abnormal bruising or bleeding.
Q. What medicines should I avoid while taking Actilyse 20mg Injection?
Actilyse 20mg Injection can interact with several medicines. If you are already taking Actilyse 20mg Injection, do not take any other medicine without talking to your doctor.
Q. When will I feel better after taking Actilyse 20mg Injection?
Actilyse 20mg Injection reduces your risk of developing blood clots in the blood vessels of your leg, lungs, heart and brain. You may not feel any difference after taking Actilyse 20mg Injection. This does not mean that the medicine is not working, therefore keep taking this medicine as prescribed.
