Manufacturer: Zydus Cadila
Salt Composition : Diclofenac, Paracetamol
Activa P Tablet should be taken with food. This will prevent you from getting an upset stomach. You should take it regularly as advised by your doctor. Do not take more or use it for a longer duration than recommended by your doctor.
Activa P Tablet is a combination of two medicines: Diclofenac and Paracetamol. These medicines work by blocking the action of chemical messengers responsible for pain, fever and inflammation (redness and swelling).
Diclofenac binds extensively to plasma albumin. The area under the plasma concentration-time curve (AUC) of diclofenac is proportional to the dose for oral doses between 25 to 150 mg. Substantial concentrations of drug are attained in synovial fluid, which is the proposed site of action for NSAIDs.
Paracetamol is readily absorbed from the gastrointestinal tract with peak plasma concentrations occurring about 30 minutes to 2 hours after ingestion. It is metabolised in the liver (90-95%) and excreted in the urine mainly as the glucuronide and sulphate conjugates. Less than 5% is excreted as unchanged paracetamol.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Activa P
Nausea
Vomiting
Stomach pain/epigastric pain
Heartburn
Diarrhea
Loss of appetite
meningitis not due to an infection.
systemic mastocytosis.
dehydration.
hepatic porphyria.
anemia.
increased risk of bleeding due to clotting disorder.
an increased risk of bleeding.
alcoholism.
Activa P Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
It is unsafe to consume alcohol with Activa P Tablet.
Activa P Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Activa P Tablet is a pain-relieving medicine. It is used to reduce pain and inflammation in conditions like rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis. It may also be used to relieve muscle pain, back pain, toothache, or pain in the ear and throat.
Drug-Drug Interaction: Activa P Tablet interact with cholesterol lowering drugs (cholestyramine), charcoal, medicine to stop vomiting (domperidone, metochlopramide), alcohol, anti HIV drug (zidovudine), blood thinner (warfarin), blood pressure lowering medicine, anti cancer or anti arthritis drug (methotrexate).
Do not chew, crush or break it. Activa P Tablet is to be taken with food.
Store below 30°C
If you miss a dose of Activa P Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
You have been prescribed this combination medicine for relieving pain and inflammation.
Take it with food to avoid getting an upset stomach.
It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how it affects you.
Avoid consuming alcohol when taking Activa P Tablet as it may cause excessive drowsiness and increase the risk of liver damage.
Do not take it with any other medicine containing acetaminophen (drugs for pain/fever or cough-and-cold) without asking your doctor first.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Activa P Tablet is to be taken with food.
Q. What is Activa P Tablet?
Activa P Tablet is a combination of two medicines: Diclofenac and Paracetamol. This medication helps in relieving pain and inflammation. It works by lowering the levels of chemical substances in the body that cause pain and inflammation. Paracetamol / Acetaminophen has an early onset of action which means that it takes very less time to start its action and it helps in relieving the symptoms till diclofenac starts working.
Q. Is it safe to use Activa P Tablet?
Yes, Activa P Tablet is safe for most of the patients. However, in some patients it may cause some unwanted common side effects like nausea, vomiting, stomach pain, heartburn, diarrhea and other uncommon and rare side effects. Inform your doctor if you experience any persistent problem while taking this medication.
Q. Can I stop taking Activa P Tablet when my pain is relieved?
Activa P Tablet, when used for long-term pain relief, should be continued for as long as advised by your physician. It can be discontinued if you are using it for short-term pain relief.
Q. Can the use of Activa P Tablet cause nausea and vomiting?
Yes, the use of Activa P Tablet can cause nausea and vomiting. Taking it with milk, food or with antacids can prevent nausea. Avoid taking fatty or fried foods along with this medication. In case of vomiting, drink plenty of water or other fluids by taking small frequent sips. Talk to your doctor if vomiting persists and you notice signs of dehydration, like dark colored and strong-smelling urine and a low frequency of urination. Do not take any other medicine without speaking to your doctor.
Q. Can the use of Activa P Tablet cause dizziness?
Yes, the use of Activa P Tablet can cause dizziness (feeling faint, weak, unsteady or lightheaded) in some patients. If you feel dizzy or lightheaded it is better to rest for some time and resume once you feel better.
Q. Can the use of Activa P Tablet cause damage to kidneys?
Yes, the long-term use of Activa P Tablet can cause damage to the kidneys. Normal kidneys produce a chemical called prostaglandins that protect them from damage. Use of painkillers lowers the levels of prostaglandins in the body leading to kidney damage on long-term use. Use of painkillers is not recommended in patients with underlying kidney disease.
Q. Are there any specific contraindications associated with the use of Activa P Tablet?
The use of Activa P Tablet is considered to be harmful in patients with known allergy to painkillers (NSAIDs) or any of the components or excipients of this medicine. The use of this medicine should preferably be avoided in patients with a history of stomach ulcers or in patients with active, recurrent stomach ulcer/bleeding. It should also be avoided in patients with the history of heart failure, high blood pressure, and liver or kidney disease.
Q. Can Activa P Tablet be taken with Vitamin B-complex?
Yes, Activa P Tablet can be taken with Vitamin B-complex preparations. While Activa P Tablet helps to relieve pain, Vitamin B-complex can help to correct the vitamin deficiency that might be causing the underlying painful condition.
Q. Is it safe to take a higher than the recommended dose of Activa P Tablet?
No, taking a higher than the recommended dose of Activa P Tablet can lead to increased chances of side effects like nausea, vomiting, heartburn, indigestion, diarrhea and can also damage your kidneys on long-term use. If you are experiencing increased severity of pain or the pain is not relieved by the recommended doses of this medicine, please consult your doctor for re-evaluation.
Q. What is the recommended storage condition for Activa P Tablet?
Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.