Manufacturer: Sanofi India Ltd
Salt Composition : Risedronate(35mg)
Actonel 35mg Tablet is best taken without food. You should take it regularly at evenly spaced intervals as per the schedule prescribed by your doctor. Taking it at the same time every day will help you to remember to take it. Do not stop taking it until you have finished, even when you feel better. It may take several days to get the full benefit of this drug. Actonel 35mg Tablet is only part of a program of treatment that may also include changes to your diet and taking calcium and vitamin supplements.
CLINICAL PHARMACOLOGY Actonel Mechanism of Action: Actonel has an affinity for hydroxyapatite crystals in bone and acts as an antiresorptive agent. At the cellular level, Actonel inhibits osteoclasts.
The absolute bioavailability of orally administered risedronate is approximately 0.6%, and is independent of formulation. Variability in the pharmacokinetics following oral administration is primarily associated with intrasubject variability in absorption.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Actonel
Headache
Musculoskeletal (bone, muscle or joint) pain
Heartburn
Diarrhea
Indigestion
low amount of calcium in the blood.
inflammation of the tissues surrounding a tooth.
achalasia of esophagus, a condition that makes swallowing difficult.
inflammation of the esophagus.
an ulcer in the esophagus.
blockage of the esophagus.
an ulcer from too much stomach acid.
Actonel 35mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Caution is advised when consuming alcohol with Actonel 35mg Tablet. Please consult your doctor.
Actonel 35mg Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Risedronate is used to prevent and treat certain types of bone loss (osteoporosis) in adults. Osteoporosis causes bones to become thinner and break more easily.
Medications such as quinapril, certain forms of didanosine (chewable/dispersible buffered tablets or pediatric oral solution), sucralfate, and bismuth subsalicylate may also interfere with absorption. Do not take these products for at least 30 minutes after taking risedronate.
Do not chew, crush or break it. Actonel 35mg Tablet is to be taken empty stomach.
Store below 30°C
If you miss a dose of Actonel 35mg Tablet, skip it and continue with your normal schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Take it first thing in the morning on an empty stomach. Do not lie down after taking the medicine.
Wait at least 1 hour before taking any other medication or eating or drinking anything.
Take calcium and vitamin D to help build your bones when taking Actonel 35mg Tablet.
Do not take it during pregnancy or breastfeeding. Tell your doctor if you become pregnant while taking Actonel 35mg Tablet.
Inform your doctor if you experience pain in jaw. This problem may be seen after dental work.
Your doctor will monitor your response to Actonel 35mg Tablet by testing your bone mineral density (BMD). This is usually done every 1-3 years.
It is important to look after your mouth and teeth while you are taking this medicine. Have regular dental check-ups and inform your dentist about taking Actonel 35mg Tablet.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Actonel 35mg Tablet is to be taken empty stomach.
Q. How to take Actonel 35mg Tablet?
Actonel 35mg Tablet should be taken in the morning after getting up on an empty stomach with a full glass of water. Do not lie down and stay fully upright for at least 30 minutes after swallowing the medicine. Avoid taking any food or medication just after taking Actonel 35mg Tablet, maintain a gap of at least 30 minutes. Take this medicine only after consulting the doctor and follow the instructions advised.
Q. Why can you not lie down after taking Actonel 35mg Tablet?
It is advised not to lie down after taking Actonel 35mg Tablet as there is a possibility that the medication might come back up into the esophagus (food pipe). As a result, the esophagus may get damaged. Staying upright will help the medicine to settle down quickly in your stomach and prevent side effects like heartburn and pain.
Q. Does Actonel 35mg Tablet cause hair loss?
Yes, Actonel 35mg Tablet can cause hair loss, but this is not a common side effect. If you experience hair loss while taking this medication immediately report to your doctor and follow the advice given.
Q. Can Actonel 35mg Tablet be used in pregnant women?
Actonel 35mg Tablet should be avoided during pregnancy. There is a lack of data regarding the use of Actonel 35mg Tablet in pregnant women. You should consult your doctor if you are pregnant or planning to get pregnant before taking this medication.
Q. What other lifestyle changes should I make?
To get maximum benefit from Actonel 35mg Tablet, there are certain lifestyle changes that you must adhere to. Include some calcium or Vitamin D rich foods for bone strength. Try to spend more time in sunlight to get natural vitamin D. Quit smoking and reduce alcohol consumption as they may harm your bones. You can take up an exercise regime such as walking and low-impact aerobics as they are good for your bones. Similarly, you can try strength-training exercises where you use your own body weight which in turn improve bone health.
