Manufacturer: Cipla Ltd
Salt Composition : Darbepoetin alfa(200mcg)
Actorise 200 Injection is a medicine that needs to be used with utmost care because it can lead to serious side effects. It is important that you seek treatment from a doctor who is experienced in providing this medical therapy. You should follow all the directions of the doctor strictly. It is given under the supervision of a healthcare professional.
ACTORISE 200MG INJECTION contains a protein 'Darbepoetin alfa', which works by providing signals to the bone marrow to make more red blood cells. As in chronic kidney disease, the kidney gets damaged and doesn't filter the blood in the way it should be leading to anemia.
A long terminal half-life characterizes the pharmacokinetic profile of darbepoetin alfa following both IV and SC administration. The most recent pharmacokinetic studies using sampling times of 27 or 28 days established that the mean terminal half-life of darbepoetin alfa is 70–105 h when administered SC.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Actorise
High blood pressure
Hypersensitivity
inadequate folic acid.
inadequate vitamin B12.
porphyria.
anemia from inadequate iron.
high blood pressure.
significant uncontrolled high blood pressure.
a heart attack.
a clot in the lung.
Actorise 200 Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
It is not known whether it is safe to consume alcohol with Actorise 200 Injection. Please consult your doctor.
Actorise 200 Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Actorise 200 Injection is used in the treatment of anemia that may have occurred due to chronic kidney disease or chemotherapy. It works by stimulating the bone marrow to produce more red blood cells.
belzutifan.
benazepril.
C1 esterase inhibitor (human)
captopril.
carfilzomib.
conestat alfa.
cyclosporine.
enalapril.
Kindly do not self administer.
Store in a refrigerator (2 - 8°C). Do not freeze.
If you miss a dose of Actorise 200 Injection, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Actorise 200 Injection helps in the treatment of anemia that may have occurred due to chronic kidney disease or cancer chemotherapy.
It is given as a single injection under your skin.
Your doctor may get your blood tests done regularly to monitor the levels of hemoglobin, blood cells and electrolytes such as potassium in your blood.
Stop taking Actorise 200 Injection and inform your doctor if you develop shortness of breath or skin rash.
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Q. How long does it take for Actorise 200 Injection to start working?
You will be able to notice an increase in the count of red blood cells (hemoglobin levels) in 2-6 weeks of starting Actorise 200 Injection. If you have any other concerns, consult your doctor.
Q. Is Actorise 200 Injection safe to use?
Actorise 200 Injection is a medicine that needs to be used with utmost care because it can lead to serious side effects and even death of the patient. It is important that you seek treatment from a doctor who is experienced in providing Actorise 200 Injection therapy. Follow all the directions strictly.
Q. Other than PRCA, can there be other reasons for not responding to Actorise 200 Injection?
You may not respond to Actorise 200 Injection if you have deficiencies of iron, folic acid or vitamin B12. It is important that you take measures to correct these deficiencies. Other reasons behind not responding to the treatment could be bleeding, infections, inflammation and bone marrow fibrosis. Therefore, consult our doctor regarding the same.
Q. Can Actorise 200 Injection be used in children?
Yes, Actorise 200 Injection is used to treat anemia due to chronic kidney disease in children who are above 1 year of age. The effectiveness of Actorise 200 Injection and side effects seen in children are similar to adults. However, consult your doctor if you are not sure.
Q. Can Actorise 200 Injection affect blood pressure?
Yes, Actorise 200 Injection can affect blood pressure. During initial therapy with Actorise 200 Injection, blood pressure should be monitored and those who have high blood pressure should take appropriate measures to control blood pressure. Your doctor may stop Actorise 200 Injection if the blood pressure remains uncontrolled.