Adriamycin 50mg (Injection)

Manufacturer: Pfizer Ltd

Salt Composition : Doxorubicin(Plain)(50mg)

Prescription
Prescription Required: Consult the Doctor & Get Your ePrescription

It is given as a drip or infusion vein with extreme caution by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. It makes contraceptive pills less effective, so it advised to both male and female to use reliable contraception during the treatment.


Basic Information

Mechanism Of Action

Adriamycin 50mg Injection is an anti-cancer medication. It works by suppressing the activity of an enzyme (topoisomerase II) involved in DNA multiplication of the cancer cells. It also forms harmful chemicals (free radicals) which cause DNA damage. This slows the growth of cancer cells and eventually kills them.

Pharmacokinets

Up to several weeks after administration, significant concentrations of doxorubicin have been found in haematopoietic cells and in several other tissues. The maximum cellular doxorubicin concentrations reached in vivo remain significantly below those at which all clonogenic leukaemic cells are killed in vitro.


Side Effects

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Adriamycin

Vomiting

Allergic reaction

Nausea

Mouth sore

Hair loss

Stomach pain

Eye disorder

Increased thirst

Arrhythmia (irregular heartbeats)

Nail disorder

Contra Indications

glucose-6-phosphate dehydrogenase (G6PD) deficiency.

anemia.

decreased blood platelets.

low levels of a type of white blood cell called neutrophils.

heart attack within the last 30 days.

cardiomyopathy, a disease of the heart muscle.

Pregnancy Related Information

Adriamycin 50mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.


Product And Alcohol Interaction

It is not known whether it is safe to consume alcohol with Adriamycin 50mg Injection. Please consult your doctor.


Breast Feeding Related Information

Adriamycin 50mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.


Indications

Adriamycin 50mg Injection helps to treat certain kinds of cancer. It may be used alone or in combination with other medicines to treat cancer in various parts of the body. Adriamycin 50mg Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells.

Interactions

Some products that may interact with this drug include: digoxin, progesterone, streptozocin, stavudine, trastuzumab, zidovudine. Other medications can affect the removal of doxorubicin from your body.

Typical Dosage

Kindly do not self administer.

Storage Requirements

Store in a refrigerator (2 - 8°C). Do not freeze.


Expert Advice

Adriamycin 50mg Injection is given as an injection into the vein under the supervision of a doctor.

Do not skip any dose and complete the course as suggested by your doctor.

Use an effective method of birth control to avoid pregnancy while taking this medication.

Your doctor may get regular blood tests done to monitor your electrolyte levels, liver function, blood cell count in your blood.

Inform your doctor if you experience fever, chills, shortness of breath and swelling of face or lips. 

How To Use

Your doctor or nurse will give you this medicine. Kindly do not self administer.


FAQs

Q. How does doxorubicin work?

Doxorubicin is anti-cancer or antineoplastic chemotherapy drug that belongs to a class of medications called anthracyclines. It slows down or stops the growth of cancer cells by interfering with DNA of the cancer cells. This helps treat the cancer.

Q. Is doxorubicin a vesicant?

Yes doxorubicin is a vesicant (irritant).