Manufacturer: Biocon
Salt Composition : Everolimus(0.5mg)
Advacan 0.5mg Tablet must be taken in a dose and duration as per the prescription. It can be taken with or without food but make sure to take it at about the same time every day. An overdose of this medicine may have serious side effects on the body. The common side effects of this medicine are weakness, sinus inflammation, infection, fever, cough, etc. If any of the side effects persist or bother you, consult the doctor immediately. Inform the doctor immediately if you experience any allergic reactions (rash, shortness of breath, coughing, swelling, etc.). Always seek medical advice if you have increased thirst or increased frequency of urination, suffer from shortness of breath, cough or fever, or need to receive any vaccination after taking this medication.
Everolimus has a mechanism of action similar to that of sirolimus. It blocks growth-driven transduction signals in the T-cell response to alloantigen and thus acts at a later stage than the calcineurin inhibitors ciclosporin and tacrolimus.
Oral everolimus is absorbed rapidly, and reaches peak concentration after 1.3-1.8 hours. Steady state is reached within 7 days, and steady-state peak and trough concentrations, and area under the concentration-time curve (AUC), are proportional to dosage.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Advacan
Weakness
Sinus inflammation
Infection
Fever
Cough
Fatigue
Stomatitis (Inflammation of the mouth)
Otitis media (infection of ear)
Diarrhea
Upper respiratory tract infection
a bad infection.
cancer or malignancy.
diabetes.
high cholesterol.
high amount of triglyceride in the blood.
hemolytic uremic syndrome, a condition that affects the kidney and the blood.
anemia.
decreased blood platelets.
Advacan 0.5mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
It is not known whether it is safe to consume alcohol with Advacan 0.5mg Tablet. Please consult your doctor.
Advacan 0.5mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Everolimus Tablets are indicated for the treatment of hormone receptor-positive, HER2/neu negative advanced breast cancer, in combination with exemestane, in postmenopausal women without symptomatic visceral disease after recurrence or progression following a non-steroidal aromatase inhibitor.
Some products that may interact with this drug include: other drugs that weaken the immune system/increase the risk of infection (such as natalizumab, rituximab), ACE inhibitors (such as captopril, lisinopril). Other medications can affect the removal of everolimus from your body, which may affect how everolimus works.
Do not chew, crush or break it. Advacan 0.5mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Store below 30°C
Advacan 0.5mg Tablet is given for the treatment of certain cancers and to prevent organ transplant rejection.
Advacan 0.5mg Tablet may affect male or female fertility; consult your doctor if you are planning to have a child.
Inform your doctor straight away if you think you are getting a sore throat or if you have a high temperature. This is because Advacan 0.5mg Tablet increases your risk of getting an infection.
While you are taking Advacan 0.5mg Tablet do not take any vaccinations without talking to your doctor first.
If you are having an operation or dental treatment, always tell the person carrying out the treatment that you are taking Advacan 0.5mg Tablet.
Do not drink grapefruit juice while you are taking this medicine. This is because a chemical in grapefruit juice can interfere with the action of Advacan 0.5mg Tablet.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Advacan 0.5mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Q. Is any monitoring required while taking Advacan 0.5mg Tablet?
Regular monitoring is required while you are on Advacan 0.5mg Tablet. The doctor will advise blood tests to see the counts of red blood cells, white blood cells, and platelets since the counts may decrease during treatment with Advacan 0.5mg Tablet. Also, blood tests will be required to check your kidney function, liver function, blood glucose levels, and cholesterol levels.
Q. What should I avoid while taking Advacan 0.5mg Tablet?
You should avoid grapefruit or grapefruit juice while taking Advacan 0.5mg Tablet. This is because taking them together may increase the levels of Advacan 0.5mg Tablet in your blood to harmful levels. Avoid the use of live vaccinations and any possible contact with individuals who have received live vaccinations.
Q. What is the most important information I need to know about Advacan 0.5mg Tablet?
Advacan 0.5mg Tablet can cause serious side effects which include severe allergic reactions, angioedema, and kidney failure which can be severe and can lead to death. It is possible that you may develop an infection or problems related to lung such as breathing problems.
Q. Is Advacan 0.5mg Tablet a chemotherapy?
Advacan 0.5mg Tablet is an anticancer medicine. It belongs to kinase inhibitor class of medicines. It works by reducing the blood supply to the tumor, which slows down the growth and spread of cancer cells.
Q. How is Advacan 0.5mg Tablet administered?
Usually, Advacan 0.5mg Tablet is taken once or twice daily. The medicine should always either be taken with food or always be taken without food. Advacan 0.5mg Tablet should be swallowed whole with water and should not be crushed or chewed.
Q. How long can you take Advacan 0.5mg Tablet?
There is no definite duration of treatment with Advacan 0.5mg Tablet. Advacan 0.5mg Tablet is continued till clinical benefit is seen or unacceptable toxicity or side effects occur.
Q. How will I know that Advacan 0.5mg Tablet is shrinking my brain tumor?
The effect of Advacan 0.5mg Tablet in shrinking the size of tumor can only be checked by getting regular brain scans. It should be done as advised by your doctor and your treatment plan.
Q. Is Advacan 0.5mg Tablet cytotoxic?
Yes, Advacan 0.5mg Tablet is cytotoxic against human cancer cells of breast, stomach, prostate, and kidneys (renal cell carcinoma).
