Manufacturer: Sun Pharmaceutical Industries Ltd
Salt Composition : Doxorubicin(Liposomal)(20mg)
Advadox 20mg Injection can be used in both adults and children. It is given as injection into vein with extreme caution by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. It makes contraceptive pills less effective, so it advised to use reliable contraception during and after 6 months of the treatment.
Advadox 20mg Injection is an anti-cancer medication. It works by damaging the genetic material (DNA) of the cancer cells and stops their growth and multiplication.
Up to several weeks after administration, significant concentrations of doxorubicin have been found in haematopoietic cells and in several other tissues. The maximum cellular doxorubicin concentrations reached in vivo remain significantly below those at which all clonogenic leukaemic cells are killed in vitro.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Advadox
Nausea
Vomiting
Rash
Weakness
Low blood platelets
Fatigue
Fever
Decreased white blood cell count (neutrophils)
Loss of appetite
Anemia (low number of red blood cells)
Constipation
Stomatitis (Inflammation of the mouth)
Diarrhea
Painful blisters on hands and feet
a bad infection.
glucose-6-phosphate dehydrogenase (G6PD) deficiency.
anemia.
decreased blood platelets.
low levels of a type of white blood cell called neutrophils.
heart attack within the last 30 days.
cardiomyopathy, a disease of the heart muscle.
Advadox 20mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
It is not known whether it is safe to consume alcohol with Advadox 20mg Injection. Please consult your doctor.
Information regarding the use of Advadox 20mg Injection during breastfeeding is not available. Please consult your doctor.
Doxorubicin is also indicated for the treatment of cancers of the ovary, prostate, stomach, thyroid; small cell cancer of lung, liver; squamous cell cancer of head and neck; multiple myeloma, Hodgkin's disease, lymphomas, acute lymphocytic leukemia (ALL), and acute myeloid leukemia (AML).
Some products that may interact with this drug include: digoxin, progesterone, streptozocin, stavudine, trastuzumab, zidovudine. Other medications can affect the removal of doxorubicin from your body, which may affect how doxorubicin works.
Kindly do not self administer.
Store in a refrigerator (2 - 8°C). Do not freeze.
Advadox 20mg Injection helps treat cancer of the breast, blood, and ovaries.
It is given through a drip into a vein (intravenous infusion) by a doctor or nurse.
It may make you feel tired or sleepy. Do not drive or do anything that requires mental focus until you know how it affects you.
Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine and for 6 months after stopping treatment.
Inform your doctor if you notice sores, discolouration or any discomfort in your mouth.
Your doctor may get regular blood tests done to monitor your blood cells, liver, and heart function during treatment with this medicine.
Inform your doctor immediately if you notice any signs of infection such as fever, sore throat or rash.
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Q. How does doxorubicin work?
Doxorubicin is anti-cancer or antineoplastic chemotherapy drug that belongs to a class of medication called anthracyclines. It slows down or stops the growth of cancer cells by interfering with DNA of the cancer cell.
Q. What is liposomal doxorubicin?
The molecules of doxorubicin are coated in a fatty capsule called as liposome. This liposome protects the body and allows the doxorubicin to remain in the blood circulation for a longer duration. This means that more amount of drug can be delivered to the cancer cells with less side effects.
