Manufacturer: Anglo-French Drugs & Industries Ltd
Salt Composition : Pseudoephedrine, Chlorpheniramine Maleate, Dextromethorphan Hydrobromide
Afdicold Tablet is taken with or without food in a dose and duration as advised by the doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your healthcare team know about all other medications you are taking as some may affect, or be affected by this medicine.
Afdicold Tablet is a combination of three medicines: Pseudoephedrine, Chlorpheniramine Maleate and Dextromethorphan Hydrobromide, which relieves dry cough. Pseudoephedrine is a decongestant which narrows the small blood vessels providing relief from congestion or stuffiness in the nose.
Unlike epinephrine and norepinephrine, pseudoephedrine is active after oral administration and is easily absorbed from the gastrointestinal tract. The onset of action occurs after 30 min and after 1–4 h the drug reaches its maximum concentration in the blood.
Chlorpheniramine has a serum half-life of approximately 20 hours in adults, and elimination from the body is primarily by metabolism to monodesmethyl and didesmethyl compounds. The half-life is increased in the presence of renal dysfunction and decreased in children.
Dextromethorphan is rapidly absorbed from the gastrointestinal tract and converted into the active metabolite dextrorphan in the liver by the cytochrome P450 enzyme CYP2D6. The average dose necessary for effective antitussive therapy is between 10 and 45 mg, depending on the individual.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Afdicold
Nausea
Stomach discomfort
Sleepiness
Nervousness
Insomnia (difficulty in sleeping)
Restlessness
Dizziness
Headache
Asthma, emphysema, tobacco smoking. Dextromethorphan is contraindicated in the treatment of chronic cough, especially when associated with excessive bronchial secretion.
Hepatic disease.
Children, infants.
Pregnancy.
Breast-feeding.
Driving or operating machinery.
MAOI therapy.
Geriatric.
Afdicold Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Caution is advised when consuming alcohol with Afdicold Tablet. Please consult your doctor.
Afdicold Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Afdicold Tablet suppresses severe dry cough and gives you relief from an itchy throat. Apart from this, it also reduces symptoms of allergy like watery eyes, sneezing and runny nose.
Drug-Drug Interaction: Afdicold Tablet may interact with blood thinners (warfarin, aspirin), antibiotics (chloramphenicol), high cholesterol-lowering medicines (cholestyramine), anti-sickness drugs (domperidone, metoclopramide), anti-allergic drugs (diphenhydramine), drugs used to reduce acid in the stomach
Do not chew, crush or break it. Afdicold Tablet may be taken with or without food, but it is better to take it at a fixed time.
Store below 30°C
If you miss a dose of Afdicold Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Afdicold Tablet helps in the treatment of dry cough.
It is usually taken only for a short time until the symptoms clear up.
Measure the syrup with a special dose-measuring spoon or cup, not a regular table spoon.
Drink extra fluids to help loosen the congestion and lubricate your throat while you are taking this medication.
Stop taking this medicine and inform your doctor if your cough persists for more than 1 week, tends to recur, or is accompanied by a fever, rash or persistent headache.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Afdicold Tablet may be taken with or without food, but it is better to take it at a fixed time.
