Manufacturer: Systopic Laboratories Pvt Ltd
Salt Composition : Ketoconazole(2% w/v), Zinc pyrithione(1% w/v)
AF-K Lotion is only meant for external use and should be used as advised by your doctor. A thin layer of the medicine should be applied only to the affected areas of the skin with clean and dry hands. Wash your hands before and after application of the medicine. If it gets into your eyes, nose, or mouth rinse with water. It may take several days to weeks for your symptoms to improve, but you should keep using this medicine regularly. The course of the treatment should be completed to ensure better efficacy of the medicine.
Ketoconazole interferes w/ biosynthesis of triglycerides and phopholipids by blocking fungal CYP450, thus altering cell membrane permeability in susceptible fungi. It also inhibits other fungal enzymes resulting in the accumulation of toxic concentrations of hydrogen peroxide.
Ketoconazole is 83.7% plasma protein (mainly albumin) bound, and 15.3% is erythrocyte bound, resulting in only 1% of free drug. Animal studies indicate strong binding to the cytochrome P-450 mono-oxygenase complex. Extensive metabolism to inactive metabolites occurs, the products being mainly excreted in the faeces.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of AF-K
Application site reactions (burning, irritation, itching and redness)
AF-K Lotion may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
No interaction found/established
Information regarding the use of AF-K Lotion during breastfeeding is not available. Please consult your doctor.
Useful in the treatment of: Itching and Pruritus Insect bites Skin allergy, Eczema and rashes Chicken pox sunburn AF-K Lotion is used as a moisturizing agent for moisturising, soothing and protecting dry, damaged, inflamed or chapped skin. Directions for use.
Drug-Drug Interaction: No interactions found. Drug-Food Interaction: Inform your doctor if you are taking any herbal supplements, vitamins or OTC medicines. Drug-Disease Interaction: No interactions found.
Shake it well and apply to the area evenly.
Store below 30°C
If you miss a dose of AF-K Lotion, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
AF-K Lotion must be applied to the affected area as prescribed by your doctor.
Do not use this medicine more often or for longer than advised by your doctor.
Before each application, wash the affected area with soap and water and dry well.
Avoid getting it in the eyes, mouth or nose. Rinse with cold water if you accidentally get it in these areas.
Stop using AF-K Lotion and inform your doctor if you notice any irritation or any other skin infection.
Inform your doctor if the treated skin area does not improve after 2-4 weeks of treatment.
This medicine is for external use only. Use this medicine in the dose and duration as advised by your doctor. Shake it well and apply to the area evenly.
