Manufacturer: Torrent Pharmaceuticals Ltd
Salt Composition : Dabigatran Etexilate(75mg)
Strip of 10 Capsule
(Inclusive of all taxes)
Afogatran 75mg Capsule is commonly used in patients with irregular heart rhythm (atrial fibrillation) to prevent clot formation. It also reduces the risk of getting clots in people who have undergone knee or hip replacement surgeries. It can be taken with or without food, but it is best to take them at the same time each day. You may need to take this medicine for many years, even for life in some cases. Do not stop taking it or change the dose without guidance from your doctor. It could quickly put you more at risk of having a heart attack, stroke, or thrombosis (formation of a blood clot within a blood vessel). You can reduce your risk of having a blood clot by making changes to your lifestyle, such as not smoking, eating a healthy diet, getting regular exercise, and losing weight if you need to.
This medicine is a direct thrombin inhibitor which works by reversibly blocking the catalytic site of thrombin and produces a rapid (within 2 hours) anticoagulant action.
Dabigatran pharmacokinetics are dose proportional after single doses of 10 to 400 mg. Given twice daily, dabigatran's accumulation factor is approximately two. Elimination Dabigatran is eliminated primarily in the urine. Renal clearance of dabigatran is 80% of total clearance after intravenous administration.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Afogatran
Bleeding
Nausea
Stomach pain
Indigestion
operation on the spine.
increased risk of bleeding due to clotting disorder.
an increased risk of bleeding.
a hemorrhage in the brain.
bleeding.
a patient who is producing milk and breastfeeding.
antiphospholipid antibody syndrome.
procedure to place indwelling epidural cathete
Afogatran 75mg Capsule may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
It is unsafe to consume alcohol with Afogatran 75mg Capsule.
Afogatran 75mg Capsule is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Afogatran 75mg Capsule is an anticoagulant or blood thinner. It helps prevent and treat blood clots. It is used to reduce the risk of stroke and heart attack. It prevents and treats clot formation in the veins of your legs, lungs, brain, and heart.
Some products that may interact with this drug include: mifepristone. Other medications can affect the removal of dabigatran from your body, which may affect how dabigatran works. Examples include cobicistat, cyclosporine, dronedarone, ketoconazole, rifampin, and St. John's wort, among others.
Afogatran 75mg Capsule may be taken with or without food.
Store below 30°C
If you miss a dose of Afogatran 75mg Capsule, please consult your doctor.
Consult a doctor before taking any medicines.
Take it as per dose and duration suggested by your doctor.
Afogatran 75mg Capsule increases your risk of bleeding. Be careful while shaving, cutting fingernails or toenails, using sharp objects or engaging in contact sports (e.g., football and wrestling).
If you are going to have a surgery or dental treatment, you may be asked to stop taking Afogatran 75mg Capsule temporarily.
Your doctor may get a blood test done to check kidney function before starting treatment with this medicine.
Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
Do not stop taking the medication without talking to your doctor.
Take this medicine in the dose and duration as advised by your doctor. Afogatran 75mg Capsule may be taken with or without food, but it is better to take it at a fixed time.
Q. When should I take Afogatran 75mg Capsule?
Mostly, Afogatran 75mg Capsule is suggested to be taken twice daily at the same time each day. The two doses should be taken at a gap of about 12 hours. If you miss a dose of Afogatran 75mg Capsule then take it as soon as possible up to 6 hours before the next scheduled dose. However, skip the missed dose if your next dose is less than 6 hours away. Never take two doses of Afogatran 75mg Capsule at the same time.
Q. Can I drink alcohol with Afogatran 75mg Capsule?
Taking alcohol while taking Afogatran 75mg Capsule can increase the effect of this medicine, thereby increasing the chance of bleeding. Regular intake of alcohol can lead to a gastric ulcer which might again cause bleeding. So, it is better to avoid alcohol while you are taking this medicine. Do consult your doctor if any such episode of bleeding occurs.
Q. Can Afogatran 75mg Capsule cause hair loss?
As compared to other blood-thinning medications, Afogatran 75mg Capsule does not usually cause hair loss. However, there do exist some rare reports of hair loss associated with Afogatran 75mg Capsule. Consult your doctor if you face hair loss while taking Afogatran 75mg Capsule to rule out any other causes of hair loss.
Q. When will I feel better after taking Afogatran 75mg Capsule?
Afogatran 75mg Capsule reduces your risk of developing blood clots in the blood vessels of your leg, lungs, heart and brain. You may not feel any difference after taking Afogatran 75mg Capsule. However, keep taking this medicine as prescribed by your doctor because you will still be getting its full benefits.
Q. Does Afogatran 75mg Capsule affect the liver?
Unlike other anticoagulants, Afogatran 75mg Capsule usually does not affect the functioning of the liver. But long-term use of Afogatran 75mg Capsule may increase the chances of mild liver injury in patients with elevated liver enzymes. However, the overall chances of developing any such problem are lower than other anticoagulants. It is advised that you inform your doctor if you have a history of liver disease before starting this medicine.
Q. How should I store Afogatran 75mg Capsule?
Afogatran 75mg Capsule should be stored at room temperature between 59°F to 86°F (15°C to 30°C). Store the medicine at a dry place and protect the capsules from moisture. Close the bottle tightly after use and keep it out of the reach of children. Once the bottle is opened, it should be used within 4 months. If unused within 4 months, please discard them safely.
Q. Can the use of Afogatran 75mg Capsule increase the risk of bleeding?
Yes, Afogatran 75mg Capsule increases the risk of bleeding. Always be careful while doing activities that may cause an injury or bleeding. Tell your doctor immediately if you notice any abnormal bruising or bleeding.
Q. Who should not take Afogatran 75mg Capsule?
People experiencing any unusual bleeding or people allergic to Afogatran 75mg Capsule should not take it. Afogatran 75mg Capsule should also be avoided by people with artificial (prosthetic) heart valves. Therefore, inform your doctor if you have ever had or plan to have a valve in your heart replaced. The use of this medicine is not recommended in patients with severe kidney disease.
