Aggrifib Injection (100ml)

Manufacturer: Aprica Pharmaceuticals Pvt Ltd

Salt Composition : Tirofiban(5mg)


Aggrifib Injection is administered under the supervision of a doctor. Your doctor will decide the dose and duration of the medicine for you. You should continue all your other medicines that are advised by the doctor for your long term treatment even after this injection. This medicine is used with caution for some people. Before taking it, you must inform the doctor if you are suffering from any bleeding disorder, kidney, or liver disease. Also, let your doctor know if you are breastfeeding and about all the other medications that you are taking regularly.



Basic Information

Mechanism Of Action

Aggrifib Injection is an antiplatelet medication. It works by preventing the platelets from sticking together, thereby decreasing the formation of harmful blood clots. This lowers the chance of heart attack or stroke.

Pharmacokinets

Tirofiban is administered as an intravenous infusion. Volume of distribution ranges from 21 to 87 L, and binding to human plasma proteins is modest at 64%. Metabolism in humans is negligible, and most drug is excreted renally with systemic clearance ranging from 4.8 to 25.8 L/h.


Side Effects

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Aggrifib

Headache

Nausea

Hematoma

Ecchymosis (discoloration of the skin resulting from bleeding underneath)

Postoperative bleeding

Blood in stool

Blood in urine

Contra Indications

Tirofiban is contraindicated in patients with any of the following: acute pericarditis, intracranial aneurysm, intracranial mass, arteriovenous malformation, any coagulopathy or history of bleeding diathesis within 30 days, severe uncontrolled hypertension (SBP > 180 mmHg and/or DBP > 110 mmHg), recent (within 6 weeks)

Pregnancy Related Information

Aggrifib Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.


Product And Alcohol Interaction

It is not known whether it is safe to consume alcohol with Aggrifib Injection. Please consult your doctor.


Breast Feeding Related Information

Aggrifib Injection should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.


Indications

Tirofiban is indicated for the prevention of early myocardial infarction in adult patients presenting with acute coronary syndromes without ST elevation (NSTE-ACS)with the last episode of chest pain occurring within 12 hours and with ECG changes and/or elevated cardiac enzymes.

Interactions

antiinflammatory drugs, NSAIDs like ibuprofen.

aspirin and aspirin-like medicines.

dipyridamole.

ginkgo.

medicines that treat or prevent blood clots like warfarin, enoxaparin, dalteparin, ticlopidine.

Typical Dosage

Kindly do not self administer.

Storage Requirements

Store below 30°C


Effects Of Missed Dosage

If you miss a dose of Aggrifib Injection, please consult your doctor.


Effects Of Overdose

Consult a doctor before taking any medicines.

Expert Advice

It increases your risk of bleeding. Be careful while shaving, cutting fingernails or toenails or using sharp objects.

Notify your doctor if you see blood in your vomit, urine or stool (black, tarry stools or bright red blood).

How To Use

Your doctor or nurse will give you this medicine. Kindly do not self administer.


FAQs

Q. Can the use of Aggrifib Injection increase the risk of bleeding?

Yes, Aggrifib Injection increases the risk of bleeding. Always be careful while doing activities that may cause an injury or bleeding. Tell your doctor immediately if you notice any abnormal bruising or bleeding.

Q. What medicines should I avoid while taking Aggrifib Injection?

Aggrifib Injection can interact with several medicines. Do not take any medicine without talking to your doctor.

Q. When will I feel better after taking Aggrifib Injection?

Aggrifib Injection reduces your risk of developing blood clots in the blood vessels of your leg, lungs, heart and brain. You may not feel any difference after taking Aggrifib Injection. However, keep taking this medicine as prescribed by your doctor because you will still be getting its full benefits.