Ajaduo 25mg / 5mg Tablet (10'S)

Manufacturer: Lupin Ltd

Salt Composition : Empagliflozin(25mg), Linagliptin(5mg)

Prescription
Prescription Required: Consult the Doctor & Get Your ePrescription

Ajaduo 25mg/5mg Tablet can be taken with or without food at any time of day but you should try to take it at the same time every day. The dose will be decided by your doctor. Don’t stop taking it without asking your doctor. If you do, your blood sugar levels may increase and put you at risk of serious complications like kidney damage and blindness. This medicine is only part of a treatment program that should include a healthy diet, regular exercise, and weight reduction as advised by your doctor.


Basic Information

Mechanism Of Action

Ajaduo 25/5Mg tablet works by blocking sodium glucose co-transporter protein in the kidneys which helps in eliminating blood glucose through urine thereby controlling blood sugar levels in type 2 diabetic patients.


Pharmacokinets

Empagliflozin is an orally active, potent and selective inhibitor of sodium glucose co-transporter 2 (SGLT2), currently in clinical development to improve glycaemic control in adults with type 2 diabetes mellitus (T2DM).

The pharmacokinetics of linagliptin has been extensively characterised in healthy subjects and patients with type 2 diabetes. After oral administration of a 5 mg dose to healthy volunteers or patients, linagliptin was rapidly absorbed, with peak plasma concentrations (median Tmax) occurring 1.5 hours post-dose.


Side Effects

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Ajaduo

Hypoglycemia (low blood glucose level)

Cough

Nasopharyngitis (inflammation of the throat and nasal passages)

Urinary tract infection

Nausea

Vomiting

Constipation

Genital fungal infection

Contra Indications

Contraindications / Precautions. Linagliptin is contraindicated in patients with a history of hypersensitivity to linagliptin, such as anaphylaxis, urticaria, angioedema, exfoliative dermatitis or other serious allergic skin condition (serious rash), or bronchial hypersensitivity.

Pregnancy Related Information

Ajaduo 25mg/5mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.


Product And Alcohol Interaction

It is unsafe to consume alcohol with Ajaduo 25mg/5mg Tablet.


Breast Feeding Related Information

Ajaduo 25mg/5mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.


Indications

Ajaduo 25 mg/5 mg Tablet 10's contains Empagliflozin and Linagliptin. It is used with a proper diet and exercise program to control high blood sugar in people with type 2 diabetes. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems.

Interactions

Drug-Drug Interactions: Ajaduo 25 mg/5 mg Tablet 10's interacts with Beta-blocker medications (such as metoprolol, propranolol, glaucoma eye drops such as timolol), Antidiabetic class of medications (e.g. glimepiride and insulin glargine) and antimanic agents (lithium).

Typical Dosage

Do not chew, crush or break it. Ajaduo 25mg/5mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

Storage Requirements

Store below 30°C


Effects Of Missed Dosage

If you miss a dose of Ajaduo 25mg/5mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.


Effects Of Overdose

Consult a doctor before taking any medicines.

Expert Advice

You have been prescribed this combination medicine as it can control blood sugar better than either one alone.

It may also reduces the risk of heart attack, heart failure or other cardiovascular events.

You should continue to exercise regularly, eat a healthy diet, and take your other diabetes medicines (if prescribed) along with Ajaduo 25mg/5mg Tablet.

Take it with food to lower your chance of having an upset stomach.

Practice good genital hygiene to prevent yeast or urinary tract infections

It may cause your body to lose too much fluid (dehydration) or you to urinate more often. Drink plenty of water, stay hydrated, and rise slowly if you have been sitting or lying down.

It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal. Check your blood sugar regularly.

Always carry some sugary food or fruit juice with you in case you experience hypoglycemia symptoms such as cold sweats, cool pale skin, tremor, and anxious feeling.

Stop taking Ajaduo 25mg/5mg Tablet and Inform your doctor if you notice joint pains or develop symptoms such as stomach pain, nausea, and/or vomiting.

How To Use

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Ajaduo 25mg/5mg Tablet may be taken with or without food, but it is better to take it at a fixed time.