Alkacel 2mg Tablet (25'S)

Manufacturer: Celon Laboratories Ltd

Salt Composition : Melphalan(2mg)


Alkacel 2mg Tablet should be taken on an empty stomach, but try to take it at the same time every day. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. It makes skin more sensitive towards sunlight, wear protective clothing or use sunscreen.


Basic Information

Mechanism Of Action

Alkacel 2mg Tablet is an anti-cancer medication. It works by damaging the genetic material (DNA and RNA) of the cancer cells. This stops their growth and multiplication.

Pharmacokinets

Melphalan was assayed in plasma by a specific HPLC method with UV detection. Plasma levels of melphalan declined in a biexponential fashion with a mean terminal half-life of 83 minutes (range 52-168 minutes). Estimated peak plasma concentrations ranged from 1.65 to 14.5 micrograms/ml.


Side Effects

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Alkacel

Nausea

Vomiting

Stomatitis (Inflammation of the mouth)

Anemia (low number of red blood cells)

Hair loss

Low blood platelets

Diarrhea

Decreased white blood cell count

Contra Indications

a bad infection.

a type of blood disorder where the red blood cells burst called hemolytic anemia.

decreased function of bone marrow.

anemia.

decreased blood platelets.

low levels of white blood cells.

low levels of granulocytes, a type of white blood cell.

inflammation of the blood vessels.


Pregnancy Related Information

Alkacel 2mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.


Product And Alcohol Interaction

It is not known whether it is safe to consume alcohol with Alkacel 2mg Tablet. Please consult your doctor.


Breast Feeding Related Information

Alkacel 2mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.


Indications

Melphalan Tablets are indicated for the palliative treatment of multiple myeloma and for the palliation of non-resectable epithelial carcinoma of the ovary. Multiple Myeloma: The usual oral dose is 6 mg (3 tablets) daily. The entire daily dose may be given at one time.

Interactions

Caplacizumab The risk or severity of bleeding can be increased when Caplacizumab is combined with Melphalan.

Carbamazepine The risk or severity of adverse effects can be increased when Carbamazepine is combined with Melphalan.

Typical Dosage

Do not chew, crush or break it. Alkacel 2mg Tablet is to be taken empty stomach.

Storage Requirements

Store in a refrigerator (2 - 8°C). Do not freeze.


Effects Of Missed Dosage

If you miss a dose of Alkacel 2mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.


Effects Of Overdose

Consult a doctor before taking any medicines.

Expert Advice

Alkacel 2mg Tablet should be taken as per dose and duration suggested by the doctor.

How To Use

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Alkacel 2mg Tablet is to be taken empty stomach.