Manufacturer: Lupin Ltd
Salt Composition : Silodosin(8mg), Dutasteride(0.5mg)
Alphacept-D 8 Capsule Combipack is advised to take it in a dose and duration as per prescription. It should be taken with food, but take at the same time regularly. Swallow the medicine as a whole without crushing or chewing it. You should not stop taking the medicine without consulting the doctor as it may lead to the worsening of your symptoms. The course of the treatment should be completed for better efficacy of the medicine.
Some common side effects of this medicine are retrograde ejaculation, dizziness, diarrhea, orthostatic hypotension, headache, nasopharyngitis, and nasal congestion. If any of the side effects persist or bother you, you must consult the doctor without delay.
Alphacept-D8 Capsule Combipack is a combination of Silodosin and Dutasteride. Silodosin works by relaxing the muscles of your bladder neck, urethra, and prostate. Thus, it relieves the symptoms of BPH.
The pharmacokinetics of silodosin is linear throughout this dose range. The exposure to the main metabolite in plasma, silodosin glucuronide (KMD-3213G), at steady-state is about 3-fold that of the parent substance. Silodosin and its glucuronide reach steady-state after 3 days and 5 days of treatment, respectively.
Pharmacokinetics: Absorption: Following administration of a single 0.5-mg dose of a soft gelatin capsule, time to peak serum concentrations (Tmax) of dutasteride occurs within 2 to 3 hours. Absolute bioavailability in 5 healthy subjects is approximately 60% (range, 40% to 94%).
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Alphacept-D
Dizziness
Orthostatic hypotension (sudden lowering of blood pressure on standing)
Headache
Ejaculation disorder
Nausea
Infection
Abdominal pain
orthostatic hypotension, a form of low blood pressure.
severe liver disease.
decreased kidney function.
severe renal impairment.
cataract surgery.
floppy iris during eye surgery.
Information regarding the use of Alphacept-D 8 Capsule Combipack during pregnancy is not available. Please consult your doctor.
Alphacept-D 8 Capsule Combipack may cause excessive drowsiness with alcohol.
Information regarding the use of Alphacept-D 8 Capsule Combipack during breastfeeding is not available. Please consult your doctor.
DUTASTERIDE+SILODOSIN is a combination of medicine primarily used to treat the symptoms of benign prostatic hyperplasia (BPH) in adults with an enlarged prostate gland. It helps to relieve symptoms such as difficulty urinating or needing to go to the toilet more often and improve your ability to urinate.
DUTASTERIDE+SILODOSIN may cause a sudden drop in your blood pressure which could lead to dizziness or fainting. Therefore, if DUTASTERIDE+SILODOSIN is taken along with blood pressure lowering medicines, it could lead to a severe decrease in blood pressure which could be lethal.
Alphacept-D 8 Capsule Combipack is to be taken with food.
Store below 30°C
If you miss a dose of Alphacept-D 8 Capsule Combipack, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Silodosin
Silodosin helps in relieving the symptoms of enlarged prostate. It does not decrease the size of the prostate.
Silodosin must be taken with food.
You will feel better within hours or days of starting the treatment. Full effect is usually seen within 2 weeks.
Silodosin may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
If you are scheduled to undergo an eye surgery due to cataract or glaucoma, inform your eye doctor about the usage of Silodosin.
Inform your doctor if you have ever been diagnosed with kidney or liver problems.
Dutasteride
Your doctor has prescribed Dutasteride to shrink the enlarged prostate and reduce the risk of urinary retention.
It may take 3 to 6 months to see the full beneficial effect of Dutasteride. Hence, continue taking the medicine as advised by your doctor.
Dutasteride is usually well tolerated. However, it may produce some mild sexual side effects such as low sexual drive.
Do not donate blood for 6 months after taking the last dose of Dutasteride.
Take this medicine in the dose and duration as advised by your doctor. Alphacept-D 8 Capsule Combipack is to be taken with food.
Silodosin
Q. What is Silodosin used for?
Silodosin is a medicine given for the treatment of difficulty in urination, urinary dribbling, a strong urge to urination, and frequent urination during the night. It is also used to relieve other symptoms associated with benign enlargement of the prostate gland. It works by reducing the tension in the muscles of the urinary tract like the prostate gland and urethra. It facilitates an easier flow of urine through the urethra, and hence, is very useful in men with difficulty of urination.
Q. When should I take Silodosin?
It is usually advised to take the dose of Silodosin daily with a meal. Prefer taking it at the same time of the day. In patients with any kidney impairment, the dose is reduced by the doctor. Patients who are unable to swallow the capsules can open the capsule and sprinkle the powder on a tablespoon of apple sauce. Consume this mixture immediately within 5 minutes without chewing and drink a glass of cool water immediately afterwards.
Q. Can I undergo cataract surgery while taking Silodosin?
In some cases, Silodosin has shown specific side effect on the eyes. It has been observed that during an eye surgery the iris tends to get floppy and pupil size becomes small in patients taking Silodosin. This makes the operation difficult and tedious. Hence, you should always inform your eye specialist about any history related to the use of Silodosin. Also, the doctor should be informed about all the medication that you are on before starting the treatment.
Q. Can Silodosin cause erectile dysfunction?
Silodosin usually does not affect erectile function. However, Silodosin may cause other sexual problems like ejaculatory dysfunction and failure to ejaculate. If you experience any side effects or uneasiness while taking this medication, contact your doctor immediately.
Q. Does Silodosin lower blood pressure?
Yes, Silodosin may cause a drop in blood pressure. This most commonly occurs while taking the first dose of this medicine. Hence, you should be cautious while driving, operating any machinery, or doing any important work during the initial days of treatment. Consult your doctor before you start taking this medication.
Q. Can I take sildenafil while taking Silodosin?
You must consult your doctor before you start taking these medications. Silodosin can sometimes cause low blood pressure and fainting. Taking sildenafil along with Silodosin can further deteriorate the condition. It could also lead to increased chances of drop in blood pressure in a few sensitive patients. As a result, there could be increase in chances of fainting which could be dangerous.
Dutasteride
Q. How long does it take for Dutasteride to work?
Dutasteride starts working within a few days of taking this medicine, and you may notice a constant improvement in your symptoms. However, for some patients, this medicine may take around 3-6 months to work. You should keep taking this medicine as prescribed by your doctor.
