Alphagan P Ophthalmic Solution (5ml)


Alphagan P Eye Drop is to be used only in the affected eye in the dose and duration as advised by the doctor. Wash your hands before using this medicine. It is advised to check the label for directions before use. Do not skip any doses and finish the full course of treatment even if you feel better. Inform your doctor if you have a known allergy to any of the ingredients in this medicine or if you are taking any other medication. It is advised not to drive or operate heavy machinery immediately after using this medicine as it may cause temporary blurring of vision and may affect your ability to drive.


Basic Information

Mechanism Of Action

Fluorophotometric studies in animals and humans suggest that brimonidine tartrate has a dual mechanism of action by reducing aqueous humor production and increasing uveoscleral outflow.


Pharmacokinets

Pharmacokinetics: After ocular administration of either a 0.1% or 0.2% solution, plasma concentrations peaked within 0.5 to 2.5 hours and declined with a systemic half-life of approximately 2 hours. In humans, systemic metabolism of brimonidine is extensive. It is metabolized primarily by the liver.

Stabilized Oxychloro Complex is used in eye drops as a gentle preservative that converts to sodium and chloride ions, oxygen and water on the ocular surface and is well tolerated in comparison to BAK and leaves no preservative residue in the eye.

Side Effects

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Alphagan P

Blurred vision

Drowsiness

Headache

Dryness in mouth

Conjunctivitis

Conjunctival hyperemia

Eye itching

Burning sensation

Follicular conjunctivitis

Allergic reaction in eye

Eyelid inflammation

Photophobia

Corneal erosion

Dry eye

Visual disorder

Dizziness

Taste change

Upper respiratory tract infection

Conjunctival blanching

Gastrointestinal discomfort

Fatigue

Stinging sensation


Contra Indications

Brimonidine is also contraindicated in patients with hypersensitivity to any component of the medication, and it should not be used in children under the age of 2 because there have been reports of apnea, bradycardia, hypothermia, hypotonia, lethargy, and unresponsiveness in infants receiving brimonidine treatment


Pregnancy Related Information

Information regarding the use of Alphagan P Eye Drop during pregnancy is not available. Please consult your doctor.


Product And Alcohol Interaction

No interaction found/established


Breast Feeding Related Information

Information regarding the use of Alphagan P Eye Drop during breastfeeding is not available. Please consult your doctor.


Indications

Alphagan P reduces the amount of fluid in the eye, which decreases pressure inside the eye. Alphagan P is a prescription eye drop used to reduce pressure inside the eyes in people with open-angle glaucoma or ocular hypertension. Alphagan P is for use in adults and children as young as 2 years old.

Interactions

Some products that may interact with this drug include: beta-blockers (such as atenolol, metoprolol, timolol eye drops), digoxin, high blood pressure medications (such as clonidine, terazosin), tricyclic antidepressants (such as amitriptyline).


Typical Dosage

Check the label for directions before use. Hold the dropper close to the eye without touching it.

Storage Requirements

Store below 30°C


Effects Of Missed Dosage

If you miss a dose of Alphagan P Eye Drop, skip it and continue with your normal schedule. Do not double the dose.


Effects Of Overdose

Consult a doctor before taking any medicines.

Expert Advice

Alphagan P Eye Drop is a combination of two medicines that lowers high pressure in the eye and reduces the risk of vision loss.

Apply pressure on the corner of the eye (close to the nose) for about 1 minute, immediately after instilling the drop.

If you wear soft contact lenses, remove them before putting in these eye drops and wait at least 15 minutes before putting your lenses back in.

Do not touch the tip of the dropper to any surface, or to your eye, to avoid contaminating the eye drops.

Wait for at least 5-10 minutes before delivering the next medication in the same eye to avoid dilution.

It may cause short term blurring of vision when first used. Use caution before driving or using machines.

It may cause temporary burning or itching sensation in the eye. Inform your doctor if this does not go away.

Make sure to use within 4 weeks of opening the bottle.


How To Use

This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Hold the dropper close to the eye without touching it. Gently squeeze the dropper and place the medicine inside the lower eyelid. Wipe off the extra liquid.