Manufacturer: Allergan India Pvt Ltd
Salt Composition : Brimonidine(0.1% w/v), Stabilized Oxychloro(0.005% w/v)
Alphagan Z Ophthalmic Solution is to be used only in the affected eye in the dose and duration as advised by the doctor. Wash your hands before using this medicine. It is advised to check the label for directions before use. Do not skip any doses and finish the full course of treatment even if you feel better. Inform your doctor if you have a known allergy to any of the ingredients in this medicine or if you are taking any other medication. It is advised not to drive or operate heavy machinery immediately after using this medicine as it may cause temporary blurring of vision and may affect your ability to drive.
It works initially by decreasing the production of aqueous humour (watery fluid similar to plasma) in the eye which decreases the pressure inside the eye. If used for a longer duration, it also works by drainage of aqueous humour.
Pharmacokinetics: After ocular administration of either a 0.1% or 0.2% solution, plasma concentrations peaked within 0.5 to 2.5 hours and declined with a systemic half-life of approximately 2 hours. In humans, systemic metabolism of brimonidine is extensive. It is metabolized primarily by the liver.
Stabilized Oxychloro Complex is used in eye drops as a gentle preservative that converts to sodium and chloride ions, oxygen and water on the ocular surface and is well tolerated in comparison to BAK and leaves no preservative residue in the eye.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Alphagan Z
Blurred vision
Drowsiness
Headache
Dryness in mouth
Conjunctivitis
Conjunctival hyperemia
Eye itching
Burning sensation
Follicular conjunctivitis
Allergic reaction in eye
Eyelid inflammation
Photophobia
Corneal erosion
Dry eye
Visual disorder
Dizziness
Taste change
Upper respiratory tract infection
Conjunctival blanching
Gastrointestinal discomfort
Fatigue
Stinging sensation
Brimonidine is also contraindicated in patients with hypersensitivity to any component of the medication, and it should not be used in children under the age of 2 because there have been reports of apnea, bradycardia, hypothermia, hypotonia, lethargy, and unresponsiveness in infants receiving brimonidine treatment
Blurred or loss of vision.
burning, dry, or itching eyes.
discharge or excessive tearing.
disturbed color perception.
halos around lights.
headache.
itching of the eye.
night blindness.
Information regarding the use of Alphagan Z Ophthalmic Solution during pregnancy is not available. Please consult your doctor.
No interaction found/established
Information regarding the use of Alphagan Z Ophthalmic Solution during breastfeeding is not available. Please consult your doctor.
Alphagan Z Ophthalmic Solution is used to reduce swelling and pressure inside the eye. This helps prevent complications of glaucoma such as blindness and improves the vision. This medicine may be used alone or with other eye drops. Glaucoma cannot be prevented.
Drug-Drug Interactions: Alphagan Z Opthalmic Solution 5 ml may have interaction with tricyclic antidepressants, antipsychotics (chlorpromazine), an alkaloid (reserpine), stimulant (methylphenidate), alpha-blocker (prazosin). Drug-Food Interactions: No interactions found/established.
Check the label for directions before use. Hold the dropper close to the eye without touching it.
Store below 30°C
If you miss a dose of Alphagan Z Ophthalmic Solution, skip it and continue with your normal schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Alphagan Z Ophthalmic Solution is a combination of two medicines that lowers high pressure in the eye and reduces the risk of vision loss.
Apply pressure on the corner of the eye (close to the nose) for about 1 minute, immediately after instilling the drop.
If you wear soft contact lenses, remove them before putting in these eye drops and wait at least 15 minutes before putting your lenses back in.
Do not touch the tip of the dropper to any surface, or to your eye, to avoid contaminating the eye drops.
Wait for at least 5-10 minutes before delivering the next medication in the same eye to avoid dilution.
It may cause short term blurring of vision when first used. Use caution before driving or using machines.
It may cause temporary burning or itching sensation in the eye. Inform your doctor if this does not go away.
Make sure to use within 4 weeks of opening the bottle.
This medicine is for external use only. Take it in the dose and duration as advised by your doctor. Check the label for directions before use. Hold the dropper close to the eye without touching it. Gently squeeze the dropper and place the medicine inside the lower eyelid. Wipe off extra liquid.
