Manufacturer: Samarth Life Sciences Pvt Ltd
Salt Composition : Recombinant Human Erythropoietin Alfa(2000IU)
Alphared 2000IU Injection is given by injection either under the skin or into a vein which will be decided by your doctor. Usually, the injections are given by a nurse or doctor. The dose depends on your body weight and the cause of your anemia. Iron supplements both before and during treatment may make this treatment more effective. Alphared 2000IU Injection needs to be stored in a fridge but used at room temperature. The most common side effects of taking this medicine include nausea, vomiting, fever, and increased blood pressure. It may also cause flu-like symptoms such as headache, tiredness, dizziness and aches and pains. These side effects are most common at the start of treatment but if they persist your doctor may be able to suggest ways of preventing or reducing them. Tell your doctor straight away if you get any serious side effects, including seizures (fits). Sometimes this medicine can cause serious blood clots that need urgent medical attention.
Erythropoietin occurs in the peritubular cells of the kidney. Anemia and hypoxia are sensed by these cells and lead to the rapid secretion of EPO, which acts on erythroid marrow.
The bioavailability of epoetin administered intraperitoneally in dialysis fluid is about 3 to 8%, but this may be increased by injecting the drug into a dry peritoneal cavity. Subcutaneous administration results in peak concentrations at about 18 hours which are 5 to 10% of those found after the same intravenous dose.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Alphared
High blood pressure
Nausea
Fever
Vomiting
Flu-like symptoms
Red cell aplasia.
Angina, anticoagulant therapy, cardiac disease, dialysis, heart failure, hemoglobin concentration greater than 11 g/dl, mortality, myocardial infarction, renal failure, renal impairment, stroke.
Hypertension.
Seizure disorder, seizures.
Alphared 2000IU Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
It is not known whether it is safe to consume alcohol with Alphared 2000IU Injection. Please consult your doctor.
Alphared 2000IU Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
RhEPO is used globally in the treatment of chronic nephropathy and anemia caused by chronic kidney disease. FDA recommends the application of chronic renal failure, malignant tumor chemotherapy, zidovudine treatment of AIDS infection, elective surgery patients.
The most frequent adverse effect associated with epoetin therapy is the worsening or development of hypertension. Other adverse effects include thrombocytosis, hyperkalemia, rise in serum urea concentration, iron deficiency, and flu-like symptoms. No drug interactions with epoetin have been reported in humans.
Kindly do not self administer.
Store in a refrigerator (2 - 8°C). Do not freeze.
If you miss a dose of Alphared 2000IU Injection, please consult your doctor.
Consult a doctor before taking any medicines.
Alphared 2000IU Injection helps in the treatment of anemia that may have occurred due to chronic kidney disease or cancer chemotherapy.
It is given as a single injection under your skin.
Your doctor may get your blood tests done regularly to monitor the levels of hemoglobin, blood cells and electrolytes such as potassium in your blood.
Monitor your blood pressure regularly while taking this medication. Inform your doctor if you notice symptoms of very high blood pressure such as severe headache, problems with your eyesight, nausea, vomiting or fits (seizures).
Stop taking Alphared 2000IU Injection and inform your doctor if you develop shortness of breath or skin rash.
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Q. How should Alphared 2000IU Injection be stored?
In the hospital, pre-filled syringes are stored unopened in a refrigerator between 2 and 8 ℃. If you are using this medicine at home, it is important that the pre-filled syringe is stored in your refrigerator. Do not store it in the freezer. Allow the pre-filled syringe to reach room temperature prior to using it. This usually takes between 15 and 30 minutes. Alphared 2000IU Injection pre-filled syringes that are being used or about to be used can be kept at room temperature (not above 25°C) for a maximum single period of 7 days. Keep these pre-filled syringes away from children and protected from light.
Q. What to do if you use too much Alphared 2000IU Injection?
Tell the doctor or nurse immediately if you think too much Alphared 2000IU Injection has been injected.
Q. When should Alphared 2000IU Injection not be used?
Alphared 2000IU Injection should not be used if the solution is clouded or you can see particles floating in it or if the medicine has expired. Refer to the expiry date on the label. You should also not use the medicine if you know or think that it may have been accidentally frozen or if there has been a refrigerator failure.
Q. Can Alphared 2000IU Injection be used in children?
Yes, Alphared 2000IU Injection is used to treat anemia caused due to chronic kidney disease in children who are above 1 year of age. The effectiveness of Alphared 2000IU Injection and side effects seen in children are similar to adults.
Q. Can Alphared 2000IU Injection affect blood pressure?
Yes, Alphared 2000IU Injection can affect blood pressure. During initial therapy with Alphared 2000IU Injection, blood pressure should be monitored and those who have high blood pressure should take appropriate measures to control blood pressure. Your doctor may stop Alphared 2000IU Injection if the blood pressure remains uncontrolled.
