Aluvia 50mg / 200mg Tablet (120'S)

Manufacturer: Abbott

Salt Composition : Ritonavir(50mg), Lopinavir(200mg)

Prescription
Prescription Required: Consult the Doctor & Get Your ePrescription

Aluvia 200mg/50mg Tablet should be used in the dose and duration as advised by your doctor. Do not skip any doses and finish the full course of treatment even if you feel better. Take it with food, as this increases the absorption of the medicine into the body. Aluvia 200mg/50mg Tablet should be used in the dose and duration as advised by your doctor. Do not skip any doses and finish the full course of treatment even if you feel better. Take it with food, as this increases the absorption of the medicine into the body.


Basic Information

Mechanism Of Action

Aluvia 200mg/50mg Tablet 120's is a combination of two antiretroviral drugs, namely: Lopinavir and Ritonavir. Lopinavir works by inhibiting the working of a protease enzyme that is essential for the reproduction of the HIV virus. Thereby, it prevents the production of the new virus.


Pharmacokinets

The pharmacokinetics of ritonavir are relatively linear after multiple doses, with apparent oral clearance averaging 7 to 9 L/h. In vitro, ritonavir is a potent inhibitor of CYP3A.

Lopinavir is primarily eliminated in the feces. Following oral administration, approximately 10.4 ± 2.3% of the administered dose is excreted in the urine and 82.6 ± 2.5% is excreted in the feces. Unchanged parent drug accounted for 2.2% and 19.8% of the administered dose in urine and feces, respectively.


Side Effects

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Aluvia

Taste change

Headache

Nausea

Diarrhea

Paresthesia (tingling or pricking sensation)

Dizziness

Cough

Abdominal pain

Throat pain

Peripheral neuropathy (tingling and numbness of feet and hand)


Contra Indications

diabetes.

high amount of triglyceride in the blood.

high cholesterol and high triglycerides.

low amount of magnesium in the blood.

low amount of potassium in the blood.

hemophilia.

a low supply of oxygen rich blood to the heart.

cardiomyopathy, a disease of the heart muscle.

Pregnancy Related Information

Aluvia 200mg/50mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.


Product And Alcohol Interaction

Caution is advised when consuming alcohol with Aluvia 200mg/50mg Tablet. Please consult your doctor.


Breast Feeding Related Information

Aluvia 200mg/50mg Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.


Indications

Aluvia 200mg/50mg Tablet 120's belongs to a class of drugs called antiretrovirals used in the treatment of HIV infection. Aluvia 200mg/50mg Tablet 120's helps in decreasing the chance of developing AIDS (acquired immunodeficiency syndrome).


Interactions

Drug-Drug Interaction: Aluvia 200mg/50mg Tablet 120's may interact with anti-allergic drugs (astemizole, terfenadine), antianxiety drugs (triazolam, midazolam), antipsychotics (quetiapine, pimozide), antidepressant (lurasidone), cholesterol-lowering medicines (simvastatin, lovastatin), antibiotics (fusidic acid).

Typical Dosage

Do not chew, crush or break it. Aluvia 200mg/50mg Tablet is to be taken with food.


Storage Requirements

Store below 30°C


Effects Of Missed Dosage

If you miss a dose of Aluvia 200mg/50mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.


Effects Of Overdose

Consult a doctor before taking any medicines.

Expert Advice

Ritonavir

Ritonavir should be taken with food.

Do not skip any doses and finish the full course of treatment even if you feel better.

Do not take antacids an hour before or two hours after taking Ritonavir.

It may cause dizziness or sleepiness. Do not drive or do anything that requires concentration until you know how it affects you.

Stop taking medications (prescribed for erectile dysfunction) like sildenafil or tadalafil while on treatment with this medicine.

Your doctor may check your liver function regularly. Inform your doctor if you develop abdominal pain, loss of appetite darkened urine or yellowing of the eyes or skin (jaundice).

Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Lopinavir

Lopinavir should be taken with food.

Do not skip any doses and finish the full course of treatment even if you feel better.

Do not take antacids an hour before or two hours after taking Lopinavir.

It may cause dizziness or sleepiness. Do not drive or do anything that requires concentration until you know how it affects you.

Stop taking medications (prescribed for erectile dysfunction) like sildenafil or tadalafil while on treatment with this medicine.

Your doctor may check your liver function regularly. Inform your doctor if you develop abdominal pain, loss of appetite darkened urine or yellowing of the eyes or skin (jaundice).

Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.


How To Use

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Aluvia 200mg/50mg Tablet is to be taken with food.


FAQs

Ritonavir

Q. What is Ritonavir used for?

It is used along with other medication for treating human immunodeficiency virus (HIV) infection. It does not completely cure HIV or AIDS

Q. Why is ritonavir used along with lopinavir?

Ritonavir is available with lopinavir as a fixed dose combination as it improves the availability of lopinavir which helps in increasing activity against HIV

Q. Is ritonavir a protease inhibitor?

Ritonavir, a protease inhibitor

Q. How does Ritonavir work and what does it inhibit?

Ritonavir belongs to a class of medication called protease inhibitors. It inhibits protease enzymes from breaking down proteins and thus prevents HIV from multiplying inside the body. It does not cure HIV completely but reduces the chances of getting acquired immunodeficiency syndrome (AIDS) and HIV related infections or cancer

Q. Why is it used as a booster?

Ritonavir is used as a booster to increase the absorption of other protease inhibitors as well as prevent other protease inhibitors from being degraded.

Lopinavir

Q. Is Lopinavir safe?

Lopinavir is safe if used at prescribed doses for the prescribed duration as advised by your doctor.