Manufacturer: Sanofi India Ltd
Salt Composition : Glimepiride(2mg), Metformin(500mg), Voglibose(0.2mg)
Keep taking this medicine, even if you feel well or your blood sugar levels are controlled. If you stop it without consulting your doctor, your blood sugar levels could rise and put you at risk of kidney damage, blindness, nerve problems and loss of limbs. Remember that it is only part of a treatment program that should also include a healthy diet, regular exercise, and weight reduction as advised by your doctor. Your lifestyle plays a big part in controlling diabetes.
Glimepiride lowers the blood sugar level increasing release of insulin hormone from the pancreas. Metformin works by decreasing the amount of glucose absorbed from the intestine, lowering the amount of sugar created by the liver and facilitating the entry of sugar into the cells.
Pharmacokinetics. Gastrointestinal absorption is complete, with no interference from meals. Significant absorption can occur within one hour, and distribution is throughout the body, 99.5% bound to plasma protein. Metabolism is by oxidative biotransformation, it is hepatic and complete.Metformin is not metabolized and is excreted unchanged in the urine, with a half-life of ~5 hrs. The population mean for renal clearance (CLr) is 510±120 ml/min. Active tubular secretion in the kidney is the principal route of metformin elimination [5].Absorption: voglibose is poorly absorbed after oral administration. However, systematic adverse effects have been observed. Metabolism: the metabolism of voglibose in liver is negligible. Excretion: The renal excretion is negligible and plasma concentations after oral dose have been undetectable.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Amaryl MV
Hypoglycemia (low blood glucose level)
Nausea
Diarrhea
Taste change
Flatulence
Stomach pain
Headache
Skin rash
Respiratory tract infection
If you have any kind of kidney or liver problem. If you have any metabolic acidosis (too much acid in the body fluids) like lactic acidosis, diabetic ketoacidosis or diabetic pre-coma. If you have a history of any kind of heart condition like shock, heart failure, etc.
Amaryl MV 2mg Tablet SR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
It is unsafe to consume alcohol with Amaryl MV 2mg Tablet SR.
Amaryl MV 2mg Tablet SR is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Amaryl MV 2mg Tablet SR belongs to a category of medicines known as anti-diabetic drugs. It is a combination of medicines used to treat type 2 diabetes mellitus in adults. It helps control blood sugar levels in people with diabetes.
Medications that affect glucose control may interact with glimepiride. Insulin and other antidiabetic medications work with glimepiride to produce a combined hypoglycemic effect. Together, these drugs may lower blood sugar to a level that results in hypoglycemia.
Do not chew, crush or break it. Amaryl MV 2mg Tablet SR is to be taken with food.
Store below 30°C
If you have missed any dose, take it as soon as you remember. If it is time for the next dose, skip the missed dose and continue your regular dosing schedule.
Do not take a double dose of medicine to compensate for a missed one. Taking double doses can be harmful as it can drop the glucose level.
An overdose of this medicine may cause hypoglycaemia (excessively low blood sugar) and may present with extreme weakness, confusion, tremors, fast heart rate, nausea, rapid breathing. You must immediately take sugar, if possible in the form of glucose. Seek emergency medical attention if you think you have used too much of this medicine.
Take it with food to lower your chance of having an upset stomach.
It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal. Carry a sugar source with you for immediate relief.
Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Amaryl MV 2mg Tablet SR is to be taken with food.
Q. What is Amaryl MV 2mg Tablet SR?
Amaryl MV 2mg Tablet SR is a combination of three medicines: Glimepiride, Metformin and Voglibose. This medicine is used in the treatment of type 2 diabetes mellitus (DM). It improves the blood glucose levels in adults when taken along with proper diet and regular exercise. Glimepiride lowers the blood glucose levels by increasing the release of insulin from the pancreas. Metformin works by lowering the glucose production in the liver and improving insulin sensitivity. Voglibose is an alpha-glucosidase inhibitor which lowers the postprandial (after meals) glucose levels in the body. This combination is not indicated for the treatment of Type 1 DM.
Q. What are the possible side effects of Amaryl MV 2mg Tablet SR?
The use of Amaryl MV 2mg Tablet SR is associated with common side effects like hypoglycemia (low blood sugar level), nausea, diarrhea, altered taste, flatulence, stomach pain, headache, skin rash and respiratory tract infection.
Q. Are there any specific conditions in which Amaryl MV 2mg Tablet SR should not be taken?
The use of Amaryl MV 2mg Tablet SR should be avoided in patients with known allergy to any of the components or excipients of this medicine. The use of this medicine is also avoided in patients with moderate to severe kidney disease and in patients with inflammatory bowel disease, colonic ulcerations and underlying metabolic acidosis including diabetic ketoacidosis.
Q. Is it safe to take alcohol while I am also taking Amaryl MV 2mg Tablet SR?
No, it is not safe to take Amaryl MV 2mg Tablet SR along with alcohol. It may lower your low blood sugar levels (hypoglycemia) and can increase the chances of lactic acidosis.
Q. Can the use of Amaryl MV 2mg Tablet SR cause hypoglycemia?
Yes, the use of Amaryl MV 2mg Tablet SR can cause hypoglycemia (low blood sugar level). Symptoms of hypoglycemia include nausea, headache, irritability, hunger, sweating, dizziness, fast heart rate, and feeling anxious or shaky. It happens more often if you miss or delay your food, drink alcohol, over-exercise or take other antidiabetic medicine along with it. So, regular monitoring of blood sugar level is important. Always keep glucose tablets, honey or fruit juice with you.
Q. What are the instructions for the storage and disposal of Amaryl MV 2mg Tablet SR?
Keep this medicine in the packet or the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
