Manufacturer: Lupin Ltd
Salt Composition : Ambrisentan(5mg)
Ambrican 5 Tablet may be taken with or without food but, it is better to take it in a dose and duration as advised by the doctor. In case, you have missed any dose than it is better to take another one as soon as you remember it. Dizziness may occur as its side effect, so do not drive or do anything that requires mental focus. You may also have other side effects like, headache, palpitations, breathlessness, runny nose, feeling sick, diarrhea or fatigue. Let your doctor know if any of these side effects bothers you or persists for a longer duration.
Ambrican 5 Tablet is an endothelin receptor blocker. It blocks the action of endothelin (a natural substance) that causes blood vessels to narrow (constrict). This narrowing increases the pressure in the blood vessels of the lungs.
Pharmacokinetics were evaluated in sixteen children treated with ambrisentan from 2.5 mg to 10.0 mg; the mean peak plasma concentration was 738 ± 452 ng/ml, mean time to peak plasma concentration was 3.2 ± 2.1 hours, and mean area under the curve plasma concentration was 6657 ± 4246 ng·hour/ml.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Ambrican
Sinus inflammation
Nasal congestion (stuffy nose)
Peripheral edema
Flushing (sense of warmth in the face, ears, neck and trunk)
anemia.
chronic heart failure.
a condition where there is formation of fibrous tissue in the lung called pulmonary fibrosis.
severe liver disease.
visible water retention.
abnormal liver function tests.
pregnancy.
a patient who is producing milk and breastfeeding.
Ambrican 5 Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
It is not known whether it is safe to consume alcohol with Ambrican 5 Tablet. Please consult your doctor.
Information regarding the use of Ambrican 5 Tablet during breastfeeding is not available. Please consult your doctor.
AMBRICAN 5MG contains Ambrisentan which belongs to a group of medicines called other antihypertensives. It is used to treat pulmonary arterial hypertension (PAH). PAH is high blood pressure in the blood vessels (the pulmonary arteries) that carry blood from the heart to the lungs.
hepatotoxicity/liver impairment.
renal impairment.
anemia.
fluid retention.
Do not chew, crush or break it. Ambrican 5 Tablet
Store below 25°C
If you miss a dose of Ambrican 5 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Your doctor has prescribed Ambrican 5 Tablet to treat high pressure in the blood vessels that carry blood from the heart to the lungs (the pulmonary arteries).
It helps improve your quality of life, exercising ability, and delay disease progression.
Your doctor may ask you to get routine blood tests done to check for anemia and to assess the functioning of your liver.
Do not drive or do anything requiring concentration until you know how Ambrican 5 Tablet affects you.
Notify your doctor if you are pregnant or planning to conceive or breastfeeding.
Females with reproductive potential should use a reliable form of birth control while using and 1 month after stopping Ambrican 5 Tablet as it is toxic to an unborn baby.
Inform your doctor if you notice weight gain, swelling of your arms and legs, or difficulty breathing.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Ambrican 5 Tablet may be taken with or without food, but it is better to take it at a fixed time.
Q. Can Ambrican 5 Tablet cause liver problems?
Yes, Ambrican 5 Tablet commonly causes an increase in liver enzymes. It may rarely cause liver injury and inflammation of the liver because of the body’s own defences (autoimmune hepatitis). Consult your doctor if you have nausea, vomiting, loss of appetite, dark-colored urine and yellowing of the skin.
Q. How should Ambrican 5 Tablet be taken?
Usually, the doctors advise to take one dose of Ambrican 5 Tablet. You can take it with or without food at any time of the day but prefer taking it at the same time each day. Swallow it whole with a glass of water. Do not crush, chew or break it into pieces.
Q. Can I stop taking Ambrican 5 Tablet on my own?
No, you should not stop taking Ambrican 5 Tablet without consulting your doctor as this may worsen your condition. Talk to your doctor if you need to stop it.
Q. What is the most important thing that I should know about Ambrican 5 Tablet?
Ambrican 5 Tablet may cause serious birth defects if taken during pregnancy. Therefore, every woman who is capable of becoming pregnant should get a pregnancy test done before starting Ambrican 5 Tablet. Additionally, during treatment with Ambrican 5 Tablet you should use two reliable methods of contraception to ensure that you do not get pregnant.
Q. What are the serious side effects of Ambrican 5 Tablet?
The serious side effects of Ambrican 5 Tablet are swelling all over the body (fluid retention), decreased sperm count and low red blood cell count (anemia). Tell your doctor if you have any unusual weight gain, tiredness, or trouble breathing.
Q. Why have I been prescribed Ambrican 5 Tablet?
Ambrican 5 Tablet is used to treat pulmonary hypertension in adults. Pulmonary hypertension is a condition wherein there is increased blood pressure in the pulmonary arteries (blood vessels that carry blood from heart to lungs). Ambrican 5 Tablet lowers the blood pressure by relaxing the pulmonary arteries, making it easier for the heart to pump blood through them.
Q. What are the symptoms of overdose of Ambrican 5 Tablet?
Taking more than the recommended dose of Ambrican 5 Tablet may cause headache, flushing, dizziness, or nausea. It may cause low blood pressure which may further lead to lightheadedness. Contact your doctor immediately or seek emergency medical services in a nearby hospital if you take more than the recommended doses of this medicine.
