Manufacturer: Icon Life Sciences
Salt Composition : Amisulpride(400mg)
Amide 400 Tablet may be taken with or without food, preferably before bedtime. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor and if you have missed a dose, take it as soon as you remember. Do not skip any doses and finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to your doctor as it may worsen your symptoms.
Amide 400 Tablet is an atypical antipsychotic. It works by modulating the action of certain chemical messengers in the brain that affect thoughts.
Amisulpride shows linear pharmacokinetics, a bioavailability of 48%, low protein binding (17%) and an elimination half-life of approximately 12 h. It is predominantly eliminated in the urine as the parent compound.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Amide
Nausea
Vomiting
Dryness in mouth
Constipation
Weight gain
Decreased blood pressure
Dystonia (involuntary muscle contractions)
Akathisia (inability to stay still)
Parkinsonism
Increased prolactin level in blood
Pheochromocytoma.
Concomitant prolactin-dependent tumours e.g. prolactinoma, breast cancer.
Movement disorders (e.g. Parkinson's disease and dementia with Lewy bodies)
Lactation.
Children before the onset of puberty.
Amide 400 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
It is unsafe to consume alcohol with Amide 400 Tablet.
Amide 400 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Amide 400 Tablet are indicated for the treatment of acute and chronic schizophrenic disorders, in which positive symptoms (such as delusions, hallucinations, thought disorders) and/or negative symptoms (such as blunted affect, emotional and social withdrawal) are prominent
Aripiprazole lauroxil Aripiprazole lauroxil may increase the antipsychotic activities of Amisulpride.
Arsenic trioxide The risk or severity of QTc prolongation can be increased when Amisulpride is combined with Arsenic trioxide.
Do not chew, crush or break it. Amide 400 Tablet
Store below 30°C
Amide 400 Tablet helps treat schizophrenia.
Take it at bedtime to avoid feeling sleepy during the day.
Use caution while driving or doing anything that requires concentration as Amide 400 Tablet can cause dizziness and sleepiness.
To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
Do not consume alcohol while on treatment with this medicine as it may worsen the side effects.
It may cause increased weight, blood sugar, cholesterol, and triglycerides (fat) levels. Eat healthy and exercise regularly.
Inform your doctor if you are pregnant, planning to conceive or breastfeeding.
Do not stop taking Amide 400 Tablet without talking to your doctor first as it may cause worsening of symptoms.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Amide 400 Tablet may be taken with or without food, but it is better to take it at a fixed time.
Q. Does Amide 400 Tablet make you sleepy?
Yes, Amide 400 Tablet may make you sleepy, drowsy, less alert, and may even blur your vision. If you experience these symptoms you should not drive or operate heavy machinery.
Q. When should I take Amide 400 Tablet?
The time of taking the medicine will be suggested by your doctor depending upon your dose. Doses up to 300 mg can be taken anytime of the day but preferably at the same time each day. Doses more than 300 mg can be taken half in the morning and half in the evening. You can take the medicine during or between meals.
Q. What does Amide 400 Tablet do to the brain?
Amide 400 Tablet belongs to antipsychotic class of medicines. It acts against dopamine receptors in the brain. Dopamine is a neurotransmitter which helps in regulating mood and behavior. Schizophrenia is associated with an overactivity of dopamine in the brain, and this overactivity may cause delusions and hallucinations. Amide 400 Tablet prevents this excessive activity of dopamine in the brain which helps in treating symptoms of schizophrenia.
Q. Does Amide 400 Tablet help with anxiety?
No, there is no data to support the use of Amide 400 Tablet in the treatment of anxiety. On the contrary, anxiety is a common side effect of Amide 400 Tablet.
