Amitril 25mg Tablet (10'S)

Manufacturer: Sigmund Promedica

Salt Composition : Amitriptyline(25mg)

Prescription
Prescription Required: Consult the Doctor & Get Your ePrescription

₹16.80

Strip of 10 Tablet

(Inclusive of all taxes)


Amitril 25mg Tablet is normally taken before bedtime because it can make you feel sleepy. It can be taken with or without food. The dose and how often you need to take it will be decided by your doctor so that you get the right amount to control your symptoms. The initial dose should be increased with great caution under close supervision. This medicine may not work straight away and it could be several weeks before you get the full effects.


Basic Information

Mechanism Of Action

AMITRIL 25MG works by increasing the levels of chemical messengers in the brain that help in regulating mood and treat depression. It also stops the transmission of pain signals from nerves to the brain thereby relieving neuropathic pain (pain from damaged nerves).


Pharmacokinets

Amitriptyline undergoes extensive hepatic presystemic elimination, and its systemic bioavailability ranges from 33% to 62% after oral administration. A highly lipophilic compound, amitriptyline is widely distributed throughout the body and extensively bound to tissue and plasma proteins .


Side Effects

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Amitril

Constipation

Dryness in mouth

Orthostatic hypotension (sudden lowering of blood pressure on standing)

Weight gain

Aggressive behavior

Nasal congestion (stuffy nose)

Sleepiness

Dizziness

Headache

Decreased libido

Nausea

Fatigue

Confusion

Tremors

Speech disorder

Palpitations

Taste change

Paresthesia (tingling or pricking sensation)

Abnormality of voluntary movements

Loss of accommodation

Atrioventricular block

Micturition disorders

Erectile dysfunction

Abnormal ECG

Decreased sodium level in blood


Contra Indications

overactive thyroid gland.

manic-depression.

suicidal thoughts.

alcoholism.

wide-angle glaucoma.

closed angle glaucoma.

heart attack within the last 30 days.

torsades de pointes, a type of abnormal heart rhythm.


Pregnancy Related Information

Amitril 25mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.


Product And Alcohol Interaction

It is unsafe to consume alcohol with Amitril 25mg Tablet.


Breast Feeding Related Information

Amitril 25mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.


Indications

  • Amitril 25 Tablet 10's is used to treat depression, neuropathic pain, chronic tension-type headache, and migraine in adults. Amitril 25 Tablet 10's is also used to treat bedwetting at night in children aged 6 years and above.

Interactions

DRUG-DISEASE INTERACTION: Amitril 25 Tablet 10's may have interactions with disease conditions such as heart problems, anticholinergic effects, depression, seizure disorders, bone marrow suppression, diabetes, schizophrenia, bipolar disorder, acute alcohol intoxication, glaucoma, thyroid problems, pheochromocytoma.


Typical Dosage

Do not chew, crush or break it. Amitril 25mg Tablet 

Storage Requirements

Store below 30°C


Effects Of Missed Dosage

If you miss a dose of Amitril 25mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.


Effects Of Overdose

Consult a doctor before taking any medicines.


Expert Advice

It may take 4 to 6 weeks for Amitril 25mg Tablet to start working. Keep taking it as prescribed.

It may cause sleepiness. Take it at bedtime and do not drive or do anything requiring concentration until you know how it affects you.

Avoid consuming alcohol when taking Amitril 25mg Tablet as it may cause excessive sleepiness.

Monitor your weight during the treatment as this medicine can cause weight gain and increased appetite.

It may cause sudden drop in your blood pressure. Rise slowly if you have been sitting or lying down.

Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.

Pay close attention to any changes, especially sudden changes, in mood, behaviors, thoughts, or feelings. This is very important when an antidepressant medicine is started or when the dose is changed.


How To Use

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Amitril 25mg Tablet may be taken with or without food, but it is better to take it at a fixed time.


FAQs

Q. What other lifestyle changes should I make to get maximum benefit of Amitril 25mg Tablet?

Antidepressants, including Amitril 25mg Tablet, are just one of several approaches to treat depression. Certain lifestyle changes can help you get maximum benefit of Amitril 25mg Tablet and help you recover fast. Keeping active and eating a healthy diet can make a significant difference to how quickly you recover from depression. Think positively and try to discuss your thoughts with others to reduce stress. Practice yoga or take up a hobby. Ensure that you have a sound sleep to calm your mind. Stay away from smoking or alcohol consumption as these will only worsen your depression. Take your medicines as prescribed even if you start feeling better.

Q. Is there anything I need to be careful about while on therapy with Amitril 25mg Tablet?

Amitril 25mg Tablet may cause drowsiness and dizziness, especially in the beginning of the treatment. So, avoid driving or using machinery until you know how the medicine affects you. Also, it is not advisable to drink alcohol during treatment with this medicine as it might increase sleepiness.

Q. Can the use of Amitril 25mg Tablet affect my sex life?

Yes, Amitril 25mg Tablet can affect sex life in both men and women. It may cause decreased sexual desire or you may experience discomfort during intercourse. Men may experience inability to develop or maintain an erection during sexual activity and may be unable to have an orgasm. If you notice these symptoms, do not stop taking the medicine but consult your doctor.

Q. I have been taking Amitril 25mg Tablet for depression since a week and recently I have been wanting to harm myself. What should I do? Is it because of the medicine?

You should immediately consult your doctor or go to the hospital. Your suicidal tendencies may have increased because of your disease or the medicine. Generally, Amitril 25mg Tablet takes about 2 weeks to show its effect but may take longer. Therefore, when you start taking Amitril 25mg Tablet, you may have thoughts about killing or harming yourself. This is more common in people who previously had suicidal tendencies or are young adults (less than 25 years old). However, the effect of medicine is different for every individual.