Amlovas-L Tablet (15'S)

Prescription
Prescription Required: Consult the Doctor & Get Your ePrescription

You can take Amlovas-L Tablet at any time of day, with or without food, but it is best to take it at the same time each day. Keep taking it for as long as advised by your doctor. Even if you feel well, do not stop this medicine on your own because high blood pressure often has no symptoms. If you stop taking it, your condition may get worse. Keeping active with regular exercise, reducing your weight and eating a healthy diet will also help control your blood pressure. Follow your doctor’s advice while taking this medicine.


Basic Information

Mechanism Of Action

Amlovas-L Tablet is a combination of two medicines: Amlodipine and lisinopril which lower blood pressure effectively. It works by relaxing blood vessels so that blood flows more smoothly and the heart can pump blood more efficiently.

Pharmacokinets

Amlodipine is a dihydropyridine calcium antagonist drug with distinctive pharmacokinetic characteristics which appear to be attributable to a high degree of ionisation. Following oral administration, bioavailability is 60 to 65% and plasma concentrations rise gradually to peak 6 to 8h after administration.

The angiotensin-converting enzyme inhibitor, lisinopril, has an oral bioavailability of 25 percent +/- 4 percent, which is unaffected by food. The accumulation half-life averages 12.6 hours despite a terminal serum half-life of approximately 40 hours.


Side Effects

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Amlovas-L

Ankle swelling

Headache

Tiredness

Palpitations

Increased potassium level in blood

Sleepiness

Cough

Taste change

Flushing (sense of warmth in the face, ears, neck and trunk)

Decreased blood pressure

Upset stomach

Contra Indications

Lisinopril is contraindicated in patients with hyperkalemia, a history of angioedema, renal failure with prior lisinopril use, bilateral renal artery stenosis, concomitant use with aliskiren in patients with diabetes mellitus, and during coadministration with a neprilysin inhibitor or within 36 hours of taking one.

Amlodipine is contraindicated in patients with known hypersensitivity to amlodipine or its dosage form components. In addition, amlodipine is relatively contraindicated in patients with cardiogenic shock, severe aortic stenosis, unstable angina, severe hypotension, heart failure, and hepatic impairment.

Pregnancy Related Information

Amlovas-L Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.


Product And Alcohol Interaction

It is unsafe to consume alcohol with Amlovas-L Tablet.


Breast Feeding Related Information

Amlovas-L Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.


Indications

Amlodipine+Lisinopril is used in the treatment of Hypertension (high blood pressure). Amlodipine + Lisinopril is a combination of two medicines: Amlodipine and lisinopril which lower blood pressure effectively.

Interactions

Drug-Food Interactions: Amlovas-L Tablet 15's may interact or may have decreased effect when used with alcohol, and high potassium foods.


Typical Dosage

Do not chew, crush or break it. Amlovas-L Tablet

Storage Requirements

Store below 30°C


Effects Of Missed Dosage

If you miss a dose of Amlovas-L Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.


Effects Of Overdose

Consult a doctor before taking any medicines.


Expert Advice

You have been prescribed Amlovas-L Tablet for the treatment of high blood pressure.

Lowering blood pressure reduces chance of future heart attack & strokes.

It may cause dizziness. Get up slowly when rising from a sitting or lying position.

Do not take Amlovas-L Tablet if you are pregnant or planning for pregnancy.


How To Use

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Amlovas-L Tablet may be taken with or without food, but it is better to take it at a fixed time.