Ampho B 50mg (Injection)

Manufacturer: Vhb Life Sciences Inc

Salt Composition : Amphotericin B(50mg)


Ampho B 50mg Injection is administered as an injection by a healthcare professional. Kindly do not self administer. Before you take this medicine, inform your doctor if you suffer from diabetes, liver/kidney problems or are on dialysis or have low potassium level in blood.


It may lead to a few common side effects like headache, vomiting, nausea, stomach cramps and fever. You may also notice some injection site reactions like pain, swelling or redness. Inform your doctor if these side effects persist for a longer duration. Please consult your doctor if you are pregnant, planning to conceive or breastfeeding.


Basic Information

Mechanism Of Action

Ampho B 50mg Injection is an antifungal medication. It kills fungi by destroying the fungal cell membrane.


Pharmacokinets

The distribution kinetics of this drug were adequately described by a three-compartment mamillary model with a total distribution volume averaging 4 liters/kg. The elimination phase half-life of amphotericin B was approximately 15 days, reflecting slow release of amphotericin B from a peripheral compartment.


Side Effects

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Ampho B

Headache

Vomiting

Nausea

Stomach cramp

Fever

Anemia (low number of red blood cells)

Heartburn

Hyperventilation (rapid breathing)

Injection site reactions (pain, swelling, redness)

Contra Indications

systemic mastocytosis.

low amount of magnesium in the blood.

low amount of potassium in the blood.

decreased kidney function.


Pregnancy Related Information

Ampho B 50mg Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.


Product And Alcohol Interaction

It is not known whether it is safe to consume alcohol with Ampho B 50mg Injection. Please consult your doctor.


Breast Feeding Related Information

Ampho B 50mg Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.


Indications

Fungal Infection, Empiric Therapy. Indicated for empiric therapy for presumed fungal infection in febrile, neutropenic patients. ...

Systemic Fungal Infections. ...

Cryptococcal Meningitis. ...

Visceral Leishmaniasis. ...

Candida auris (Off-label) ...

Histoplasmosis (Orphan)

Interactions

Some products that may interact with this drug include: anti-cancer drugs (such as mechlorethamine, nitrogen mustard), azole antifungals (such as ketoconazole, itraconazole), cidofovir, digoxin, flucytosine, medications that affect the kidneys (including pentamidine, tacrolimus, aminoglycosides such as gentamicin), ...


Typical Dosage

Kindly do not self administer.

Storage Requirements

Store in a refrigerator (2 - 8°C). Do not freeze.


Effects Of Missed Dosage

If you miss a dose of Ampho B 50mg Injection, please consult your doctor.


Effects Of Overdose

 Consult a doctor before taking any medicines.

Expert Advice

It is usually given as an injection over 1-2 hours under the supervision of a medical professional.

Ampho B 50mg Injection can cause rash, chills, headache, and tiredness during initial days of the treatment, but these may fade away with time.

Your doctor may ask you for regular blood tests to monitor your blood sugar, potassium, magnesium and kidney function.

Inform your doctor immediately if you notice pain or blood upon urination, swelling of the face and trouble breathing.

Inform your doctor if you are pregnant, planning pregnancy or breastfeeding. 

How To Use

Your doctor or nurse will give you this medicine. Kindly do not self administer.


FAQs

Q. Is Ampho B 50mg Injection fungistatic or fungicidal?

Ampho B 50mg Injection is fungicidal in nature, it acts by killing the fungus

Q. Is Ampho B 50mg Injection light sensitive?

Ampho B 50mg Injection is not light sensitive

Q. What is Ampho B 50mg Injection liposomal?

Liposomal Ampho B 50mg Injection is a lipid-associated formulation. Liposomal encapsulation or incorporation into a lipid complex of Ampho B 50mg Injection can substantially improves drug safety especially nephrotoxicity associated with the drug

Q. Is Ampho B 50mg Injection an antibiotic?

Yes, Ampho B 50mg Injection is an antifungal antibiotic for the treatment of serious infections caused by fungi like fungal infections of one or more deep organs of the body, suspected fungal infections in patients with a raised temperature and neutropenia (reduced number of white blood cells [neutrophils]) and Visceral leishmaniasis (disease caused by a parasite)