Amphogard 50mg (Injection)

Manufacturer: Zydus Cadila

Salt Composition : Amphotericin B(50mg)


Amphogard 50mg Injection is generally administered by a doctor or a nurse. You should not self-administer this medicine at home. The dose and duration of the treatment will depend on the severity of your condition. You should get the injection as long as your doctor has prescribed it.


The most common side effects of this medicine are decreased potassium level in the blood, nausea, vomiting, chills, and fever. Consult your doctor if these side effects persist for a longer duration or get worse. They may be able to suggest ways to prevent or reduce the side effects.


To make sure it is safe for you, before using this medicine, let your doctor know if you have any preexisting medical conditions or if you are taking any other medicines. Let your doctor also know if you are pregnant or breastfeeding, as it may cause harmful effects to the developing baby.


Basic Information

Mechanism Of Action

Amphogard 50mg Injection is an antifungal medication. It kills fungi by destroying the fungal cell membrane.


Pharmacokinets

Based on total amphotericin B concentrations measured within a dosing interval (24 hours) after administration of AmBisome, the mean half-life was 7-10 hours. However, based on total amphotericin B concentration measured up to 49 days after dosing of AmBisome, the mean half-life was 100-153 hours.


Side Effects

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Amphogard

Decreased potassium level in blood

Nausea

Vomiting

Chills

Fever

Contra Indications

systemic mastocytosis.

low amount of magnesium in the blood.

low amount of potassium in the blood.

decreased kidney function.

Pregnancy Related Information

Amphogard 50mg Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.


Product And Alcohol Interaction

It is not known whether it is safe to consume alcohol with Amphogard 50mg Injection. Please consult your doctor.


Breast Feeding Related Information

Amphogard 50mg Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.


Indications

Fungal Infection, Empiric Therapy. Indicated for empiric therapy for presumed fungal infection in febrile, neutropenic patients. ...

Systemic Fungal Infections. ...

Cryptococcal Meningitis. ...

Visceral Leishmaniasis. ...

Candida auris (Off-label) ...

Histoplasmosis (Orphan)

Interactions

Some products that may interact with this drug include: anti-cancer drugs (such as mechlorethamine, nitrogen mustard), azole antifungals (such as ketoconazole, itraconazole), cidofovir, digoxin, flucytosine, medications that affect the kidneys (including pentamidine, tacrolimus, aminoglycosides such as gentamicin), ...


Typical Dosage

Kindly do not self administer.

Storage Requirements

Store in a refrigerator (2 - 8°C). Do not freeze.


Effects Of Missed Dosage

If you miss a dose, please consult your doctor.

Effects Of Overdose

Consult a doctor before taking any medicines.

How To Use

Your doctor or nurse will give you this medicine. Kindly do not self administer.


FAQs

Q. How is Amphogard 50mg Injection administered?

Amphogard 50mg Injection should be administered under the supervision of a trained healthcare professional or a doctor only and should not be self-administered. The dose will depend on the condition you are being treated for and will be decided by your doctor. Follow your doctor’s instructions carefully to get maximum benefit from Amphogard 50mg Injection.

Q. Is Amphogard 50mg Injection fungistatic or fungicidal?

Amphogard 50mg Injection is fungicidal in nature, which means it acts by killing the fungus.

Q. What should I tell my doctor before starting treatment with Amphogard 50mg Injection?

Before starting treatment with Amphogard 50mg Injection, tell your doctor if you have any other health problems, like kidney or liver-related issues. This is because certain medical conditions may affect your treatment and you may even need dose modifications. Let your doctor know about all the other medicines you are taking because they may affect, or be affected by, this medicine. Inform your doctor if you are planning a baby, if you are pregnant or breastfeeding.

Q. Is Amphogard 50mg Injection an antibiotic?

Yes, Amphogard 50mg Injection is an antifungal antibiotic for the treatment of infections caused by fungi like fungal infections of one or more deep organs of the body, suspected fungal infections in patients with a raised temperature and neutropenia (reduced number of white blood cells and Visceral leishmaniasis (an infectious disease caused by a parasite).