Manufacturer: Bharat Serums & Vaccines Ltd
Salt Composition : Amphotericin B(50mg)
Vial of 1 Injection
(Inclusive of all taxes)
Amphotret 50mg Injection is administered as an injection by a healthcare professional. Kindly do not self administer. Before you take this medicine, inform your doctor if you suffer from diabetes, liver/kidney problems or are on dialysis or have low potassium level in blood.
It may lead to a few common side effects like headache, vomiting, nausea, stomach cramps and fever. You may also notice some injection site reactions like pain, swelling or redness. Inform your doctor if these side effects persist for a longer duration. Please consult your doctor if you are pregnant, planning to conceive or breastfeeding.
Amphotret 50mg Injection is an antifungal medication. It kills fungi by destroying the fungal cell membrane.
Amphotericin B binds to ergosterol in the fungal cell membrane, which leads to the formation of pores, ion leakage and ultimately fungal cell death.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Amphotret
Headache
Vomiting
Nausea
Stomach cramp
Fever
Anemia (low number of red blood cells)
Heartburn
Hyperventilation (rapid breathing)
Injection site reactions (pain, swelling, redness)
systemic mastocytosis.
low amount of magnesium in the blood.
low amount of potassium in the blood.
decreased kidney function.
Amphotret 50mg Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
It is not known whether it is safe to consume alcohol with Amphotret 50mg Injection. Please consult your doctor.
Amphotret 50mg Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Use with caution
Below 9years: Contraindicated
Amphotericin B injection is used to treat serious and potentially life-threatening fungal infections. Amphotericin B injection is in a class of medications called antifungals. It works by slowing the growth of fungi that cause infection.
AMPHOTERICIN B may interact with an anti-HIV drug (zidovudine), immunosuppressant (ciclosporin), antifungal (flucytosine), water pills (furosemide), anticancer drug (methotrexate).
Kindly do not self administer.
Store in a refrigerator (2 - 8°C). Do not freeze.
If you miss a dose of Amphotret 50mg Injection, please consult your doctor.
Consult a doctor before taking any medicines.
It is usually given as an injection over 1-2 hours under the supervision of a medical professional.
Amphotret 50mg Injection can cause rash, chills, headache, and tiredness during initial days of the treatment, but these may fade away with time.
Your doctor may ask you for regular blood tests to monitor your blood sugar, potassium, magnesium and kidney function.
Inform your doctor immediately if you notice pain or blood upon urination, swelling of the face and trouble breathing.
Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Q. Is Amphotret 50mg Injection fungistatic or fungicidal?
Amphotret 50mg Injection is fungicidal in nature, it acts by killing the fungus
Q. Is Amphotret 50mg Injection light sensitive?
Amphotret 50mg Injection is not light sensitive
Q. What is Amphotret 50mg Injection liposomal?
Liposomal Amphotret 50mg Injection is a lipid-associated formulation. Liposomal encapsulation or incorporation into a lipid complex of Amphotret 50mg Injection can substantially improves drug safety especially nephrotoxicity associated with the drug
Q. Is Amphotret 50mg Injection an antibiotic?
Yes, Amphotret 50mg Injection is an antifungal antibiotic for the treatment of serious infections caused by fungi like fungal infections of one or more deep organs of the body, suspected fungal infections in patients with a raised temperature and neutropenia (reduced number of white blood cells [neutrophils]) and Visceral leishmaniasis (disease caused by a parasite)
Q. Is Amphotret 50mg Injection testing dose needed?
Yes, administration of Amphotret 50mg Injection is associated with allergy (severe and serious allergic) reaction, therefore it is recommended to administer a test dose before starting the therapy to check for sensitivity
Q. How is Amphotret 50mg Injection administered?
Amphotret 50mg Injection is either administered as intravenous injection or infusion by a registered medical professional only
Q. How does Amphotret 50mg Injection cause nephrotoxicity and hyperkalemia?
Amphotret 50mg Injection can disrupt the lipid components of human kidney cells, thereby causing nephrotoxicity. The exact mechanism of hypokalemia is not known, but kidney damage may result in excessive loss of potassium in urine.
