Manufacturer: Intas Pharmaceuticals Ltd
Salt Composition : Amlodipine(5mg), Hydrochlorothiazide(12.5mg)
Strip of 10 Tablet
(Inclusive of all taxes)
Amtas HT Tablet is a combination medicine used in the treatment of hypertension (high blood pressure). It also helps to reduce the risk of stroke and heart attack. This medicine should be used along with a proper diet, salt restriction, and regular exercise for best results. It should be taken with or without food preferably in the morning, to avoid frequent urination at night. This medicine may cause dehydration, so it is better to take plenty of fluids. Inform doctor if you develop extreme thirst and muscle weakness. Some patients may develop swelling of ankle as a side effect of using this medicine.
Hydrochlorthiazide acts by removing excess fluid and salt from the body by increasing the urine output thus help reduce blood volume and pressure. It also reduces the load on the heart.
Amlodipine is a dihydropyridine calcium antagonist drug with distinctive pharmacokinetic characteristics which appear to be attributable to a high degree of ionisation. Following oral administration, bioavailability is 60 to 65% and plasma concentrations rise gradually to peak 6 to 8h after administration.
Absorption of hydrochlorothiazide is reduced in patients with congestive heart failure. Peak plasma concentrations are observed within 1 to 5 hours of dosing, and range from 70 to 490 ng/mL following oral doses of 12.5 to 100 mg.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Amtas HT
Glucose intolerance
Sleepiness
Ankle swelling
Headache
Flushing (sense of warmth in the face, ears, neck and trunk)
Tiredness
Palpitations
Nausea
Increased blood uric acid
Decreased potassium level in blood
Altered blood lipid level
Amlodipine is contraindicated in patients with known hypersensitivity to amlodipine or its dosage form components. In addition, amlodipine is relatively contraindicated in patients with cardiogenic shock, severe aortic stenosis, unstable angina, severe hypotension, heart failure, and hepatic impairment.
General Information. ...
Asthma, penicillin hypersensitivity, sulfonamide hypersensitivity, thiazide diuretic hypersensitivity. ...
Hepatic disease. ...
Diabetes mellitus, hyperglycemia. ...
Anuria, hypovolemia, renal disease, renal failure, renal impairment.
Amtas HT Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
It is unsafe to consume alcohol with Amtas HT Tablet.
Amtas HT Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Amlodipine+Hydrochlorothiazide is used in the treatment of Hypertension (high blood pressure). Amlodipine + Hydrochlorothiazide is a combination of two medicines: Amlodipine and hydrochlorothiazide which lower blood pressure effectively.
Steroidal medicines if taken along with this medicine can lead to salt imbalances particularly reduced potassium levels. Anti-inflammatory or painkiller medicines can reduce the blood pressure-lowering action of this medicine and the patient needs to be monitored closely.
Do not chew, crush or break it. Amtas HT Tablet may be taken with or without food, but it is better to take it at a fixed time.
Store below 30°C
If you miss a dose of Amtas HT Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Amtas HT Tablet helps in the treatment of high blood pressure.
It also lowers your risk of stroke and heart attack.
Take it in the morning with breakfast to avoid getting up at night to urinate.
It may cause dizziness or sleepiness. Don't drive or do anything requiring concentration until you know how it affects you.
It may cause you to feel lightheaded or weak especially when you stand up (orthostatic hypotension). Rise slowly if you have been sitting or lying down.
It may cause dehydration. Drink plenty of fluids and Inform your doctor if you develop extreme thirst, muscle weakness or very dry mouth.
Your doctor may regularly monitor your blood pressure, kidney function and the levels of salts such as potassium in your blood while you are taking this medicine.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Amtas HT Tablet may be taken with or without food, but it is better to take it at a fixed time.
