Manufacturer: Intas Pharmaceuticals Ltd
Salt Composition : Amlodipine(5mg), Lisinopril(5mg)
You can take Amtas LP Tablet at any time of day, with or without food, but it is best to take it at the same time each day. Keep taking it for as long as advised by your doctor. Even if you feel well, do not stop this medicine on your own because high blood pressure often has no symptoms. If you stop taking it, your condition may get worse. Keeping active with regular exercise, reducing your weight and eating a healthy diet will also help control your blood pressure. Follow your doctor’s advice while taking this medicine.
It may cause side effects like ankle swelling, headache, cough, weakness, and tiredness. It may also cause dizziness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. This might raise the level of potassium in the blood, hence avoid potassium rich food or supplements. You may be asked for regular monitoring of blood pressure, kidney function, and electrolytes level while on the treatment.
Before taking it, let your doctor know if you have any liver or kidney problems. Pregnant or breastfeeding women should also consult their doctor for advice before taking this medicine. You also need to tell your doctor what other medicines you are taking especially those used to treat high blood pressure or heart conditions.
Amlodipine and lisinopril work by relaxing the blood vessels, thus making it easier for the blood to pass through the blood vessels and lowering the blood pressure. It also improves the blood and oxygen supply to the heart muscle and prevents chest pain due to angina.
Amlodipine is a dihydropyridine calcium antagonist drug with distinctive pharmacokinetic characteristics which appear to be attributable to a high degree of ionisation. Following oral administration, bioavailability is 60 to 65% and plasma concentrations rise gradually to peak 6 to 8h after administration.
The drug is not metabolized but is eliminated via the kidneys. Lisinopril probably undergoes glomerular filtration, tubular secretion, and tubular reabsorption. There is no pharmacokinetic interaction between lisinopril and furosemide.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Amtas LP
Ankle swelling
Headache
Tiredness
Palpitations
Increased potassium level in blood
Sleepiness
Cough
Taste change
Flushing (sense of warmth in the face, ears, neck and trunk)
Decreased blood pressure
Upset stomach
Lisinopril is contraindicated in patients with hyperkalemia, a history of angioedema, renal failure with prior lisinopril use, bilateral renal artery stenosis, concomitant use with aliskiren in patients with diabetes mellitus, and during coadministration with a neprilysin inhibitor or within 36 hours of taking one.
Amlodipine is contraindicated in patients with known hypersensitivity to amlodipine or its dosage form components. In addition, amlodipine is relatively contraindicated in patients with cardiogenic shock, severe aortic stenosis, unstable angina, severe hypotension, heart failure, and hepatic impairment.
Amtas LP Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
It is unsafe to consume alcohol with Amtas LP Tablet.
Amtas LP Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Amlodipine+Lisinopril is used in the treatment of Hypertension (high blood pressure). Amlodipine + Lisinopril is a combination of two medicines: Amlodipine and lisinopril which lower blood pressure effectively.
If you take other medicines that lower blood pressure, such as ramipril or lisinopril, at the same time as amlodipine, the combination can sometimes lower your blood pressure too much.
Do not chew, crush or break it. Amtas LP Tablet may be taken with or without food
Store below 30°C
If you miss a dose of Amtas LP Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
You have been prescribed Amtas LP Tablet for the treatment of high blood pressure.
Lowering blood pressure reduces chance of future heart attack & strokes.
It may cause dizziness. Get up slowly when rising from a sitting or lying position.
Do not take Amtas LP Tablet if you are pregnant or planning for pregnancy.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Amtas LP Tablet may be taken with or without food, but it is better to take it at a fixed time.
