Manufacturer: Arinna Lifescience Pvt Ltd
Salt Composition : Sodium Valproate(133.5mg), Valproic Acid(58mg)
Strip of 10 Tablet Cr
(Inclusive of all taxes)
Amvalor Chrono 200 Tablet CR should be taken with food. Your doctor will decide the correct dose for you. This may increase gradually until your condition is stable. This medicine may take several weeks to work but it is important to take it regularly to get the benefit. Do not stop taking it, even if you feel fine unless your doctor advises you to. You may have more seizures, or your bipolar disorder may get worse.
The most common side effects of this medicine include nausea, vomiting, loss of appetite, swelling of gums, headache, sleepiness, tremor, hair loss and liver injury. Most side effects wear off, but if they bother you or do not go away, tell your doctor. There may be ways of preventing or reducing these effects.
Before taking this medicine, tell your doctor if you have kidney or liver problems, meningitis or depression or suicidal thoughts. Also let your doctor know about all other medications you are using as some may affect, or be affected by, this medicine, including contraceptive pills. If you are pregnant or breastfeeding, Amvalor Chrono 200 Tablet CR can be taken if it is clearly needed but the dose may be adjusted. You should avoid driving or riding a bicycle if this medicine makes you drowsy or dizzy. You may need frequent blood tests to check how you are responding to this medicine.
Amvalor Chrono 200 Tablet CR is a combination of two antiepileptic medicines: Sodium Valproate and Valproic Acid. They work together to control seizures or fits by decreasing the abnormal and excessive activity of the nerve cells in the brain.
Sodium valproate (VPA) was first marketed in the United States in 1978. In this pilot study of pharmacokinetics and toxicity, VPA was added to the treatment regimens of 20 patients (10 adults and 10 children) with intractable seizures. The drug was absorbed and excreted rapidly; the mean half-life was 9.6 hours.Valproic acid exhibits its pharmacologic effects in a couple of ways, such as by acting on GABA (γ aminobutyric acid) levels in the CNS, blocking voltage-gated ion channels, and inhibiting histone deacetylase.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Amvalor Chrono
Nausea
Vomiting
Weight gain
Loss of appetite
Gum swelling
Headache
Sleepiness
Tremors
Hair loss
Liver injury
Allergic reactions
Alpers' disease
Hypersensitivity
Lactation
Liver disease
Liver impairment
Pregnancy
Urea cycle disorder
Amvalor Chrono 200 Tablet CR is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
It is unsafe to consume alcohol with Amvalor Chrono 200 Tablet CR.
Amvalor Chrono 200 Tablet CR is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Use with caution
Below 9years: Contraindicated
Sodium Valproate + Valproic Acid is a combination of two antiepileptic medicines: Sodium Valproate and Valproic Acid. They work together to control seizures or fits by decreasing the abnormal and excessive activity of the nerve cells in the brain.
SODIUM VALPROATE+VALPROIC ACID may have interaction with pain killers (aspirin), anti-epileptics (phenobarbital, primidone, phenytoin, carbamazepine, lamotrigine, felbamate), anti-HIV (zidovudine), anti-depressant (amitriptyline, sertraline), anti-psychotic (quetiapine, olanzapine, risperidone), hormone (levonorgestrel), anti-malarial (mefloquine), antacid (cimetidine), antibiotics (imipenem, meropenem, erythromycin), bile-acid sequestrant (cholestyramine), benzodiazepine (clonazepam, diazepam).
Do not chew, crush or break it. Amvalor Chrono 200 Tablet CR is to be taken with food.
Store below 30°C
If you miss a dose of Amvalor Chrono 200 Tablet CR, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
You have been prescribed Amvalor Chrono 200 Tablet CR for treatment and prevention of seizures.
Take it at the same time every day to maintain consistent levels in your body.
Do not drive or do anything that requires mental focus until you know how Amvalor Chrono 200 Tablet CR affects you.
Avoid consuming alcohol when taking Amvalor Chrono 200 Tablet CR, as it may cause excessive sleepiness or drowsiness.
Monitor your weight during the treatment as Amvalor Chrono 200 Tablet CR can cause weight gain.
Your doctor may monitor Amvalor Chrono 200 Tablet CR level, blood counts and liver function regularly throughout your treatment. Inform your doctor if you develop fever, stomach pain, nausea or yellowing of your eyes or skin.
Do not take Amvalor Chrono 200 Tablet CR if you are pregnant or planning to conceive or breastfeeding.
Do not stop taking the medication suddenly without talking to your doctor as it may increase the seizure frequency.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Amvalor Chrono 200 Tablet CR is to be taken with food.
Q. Can the use of Amvalor Chrono 200 Tablet CR cause sleepiness or drowsiness?
Yes, Amvalor Chrono 200 Tablet CR may make you feel drowsy or sleepy. Avoid driving, operating machinery, working at heights or participating in potentially dangerous activities. Inform your doctor if you experience such an episode while taking this medicine.
Q. Can I drink alcohol while taking Amvalor Chrono 200 Tablet CR?
No, avoid drinking alcohol while taking Amvalor Chrono 200 Tablet CR. Drinking alcohol will increase the side effects caused by Amvalor Chrono 200 Tablet CR.
Q. Can Amvalor Chrono 200 Tablet CR be stopped when epilepsy symptoms are relieved?
No, Amvalor Chrono 200 Tablet CR should be continued as advised by the doctor. Stopping Amvalor Chrono 200 Tablet CR suddenly may cause the symptoms to reappear that too with increased frequency. If any problems are experienced due to Amvalor Chrono 200 Tablet CR, consult the doctor for re-evaluation.
Q. Will a higher than the recommended dose of Amvalor Chrono 200 Tablet CR be more effective?
No, taking a higher than the recommended dose may not be more effective, rather it may increase the chances of having serious side effects and toxicity. If the recommended doses do not relieve your symptoms or there is an increased severity of your symptoms, please consult your doctor.
Q. What are the instructions for the storage and disposal of Amvalor Chrono 200 Tablet CR?
Keep this medicine in the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
