Manufacturer: Psycormedies
Salt Composition : Amitriptyline(12.5mg), Chlordiazepoxide(5mg)
Strip of 10 Tablet
(Inclusive of all taxes)
Amypres C 12.5 mg/5 mg Tablet is taken with or without food. However, it is advised to take it at a fixed time each day to maintain a consistent level of medicine in the blood. In case you miss a dose of this medicine, take it as soon as you remember. Never skip any dose and finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to the doctor as it may worsen your symptoms. Taking this medicine for a long time may require regular monitoring of blood and liver functions.
Some common side effects of this medicine include constipation, difficulty in urination, weight gain, confusion, orthostatic hypotension (sudden lowering of blood pressure on standing). This medicine may cause weight loss. In case of losing weight, consult a dietitian for dietary supplements or try to increase your food portion. Most of the common side effects tend to be mild. Your doctor may be able to suggest ways of preventing or reducing side effects if they bother you or do not go away. Serious side effects are rare. Remember to inform your doctor if you develop any unusual changes in mood as it may lead to suicidal thoughts.
Take caution while taking medicine if you are suffering from liver disease. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
Amitriptyline + Chlordiazepoxide is a combination of two medicines: Amitriptyline and Chlordiazepoxide, which treats depression. Amitriptyline is a tricyclic antidepressant which increases the levels of chemical messengers in the brain that help in regulating the mood and treat depression.
Amitriptyline undergoes extensive hepatic presystemic elimination, and its systemic bioavailability ranges from 33% to 62% after oral administration [2]. A highly lipophilic compound, amitriptyline is widely distributed throughout the body and extensively bound to tissue and plasma proteins
Pharmacokinetics. Chlordiazepoxide is a long-acting benzodiazepine drug. The half-life of Chlordiazepoxide is 5 – 30 hours but has an active benzodiazepine metabolite (desmethyldiazepam), which has a half-life of 36 – 200 hours.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Amypres C
Constipation
Difficulty in urination
Weight gain
Confusion
Orthostatic hypotension (sudden lowering of blood pressure on standing)
Tiredness
Blurred vision
Dryness in mouth
Increased heart rate
Uncoordinated body movements
Depression
Memory impairment
Inform your doctor before taking AMITRIPTYLINE+CHLORDIAZEPOXIDE if you have bipolar disorder, eye problems, urination problems, seizures, thyroid problems, kidney or liver problems or if you are due to have any surgery. Consult your doctor immediately if you have suicidal thoughts, such as killing or harming yourself.
Amypres C 12.5 mg/5 mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
It is unsafe to consume alcohol with Amypres C 12.5 mg/5 mg Tablet.
Amypres C 12.5 mg/5 mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Chlordiazepoxide and amitriptyline combination is used to treat mental depression that occurs with anxiety or nervous tension. The Non-FDA approved indications are anxiety, post-traumatic stress disorder, insomnia, chronic pain (diabetic neuropathy, fibromyalgia), irritable bowel syndrome, interstitial cystitis (bladder pain syndrome), migraine prophylaxis, postherpetic neuralgia, and sialorrhea.
Taking these drugs together could increase your risk of irregular heart rate. Sertraline, fluoxetine, and paroxetine. Taking these drugs together can increase the side effects of amitriptyline/chlordiazepoxide. These can include dizziness, confusion, and heart attack.
Do not chew, crush or break it. Amypres C 12.5 mg/5 mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Store below 30°C
If you miss a dose of Amypres C 12.5 mg/5 mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Amypres C 12.5 mg/5 mg Tablet is prescribed for the treatment of depression.
It can take a week or two after starting this treatment before the effect begins to build up, and 4-6 weeks before you feel the full benefit. Do not stop taking it after a week or two, feeling it is not helping.
Do not stop taking Amypres C 12.5 mg/5 mg Tablet unless your doctor tells you to do so. Stopping treatment suddenly can cause problems and your doctor will probably want you to reduce your dose gradually when this becomes necessary.
Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress.
Inform your doctor if you are taking any other antidepressants.
Inform your doctor immediately if you get thoughts about harming yourself or ending your life.
Avoid alcohol while taking Amypres C 12.5 mg/5 mg Tablet.
If you have diabetes, you will be asked to monitor your blood glucose level regularly as Amypres C 12.5 mg/5 mg Tablet may affect the levels of sugar in your blood.
Amypres C 12.5 mg/5 mg Tablet is prescribed for the treatment of depression.
It can take a week or two after starting this treatment before the effect begins to build up, and 4-6 weeks before you feel the full benefit. Do not stop taking it after a week or two, feeling it is not helping.
Do not stop taking Amypres C 12.5 mg/5 mg Tablet unless your doctor tells you to do so. Stopping treatment suddenly can cause problems and your doctor will probably want you to reduce your dose gradually when this becomes necessary.
Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress.
Inform your doctor if you are taking any other antidepressants.
Inform your doctor immediately if you get thoughts about harming yourself or ending your life.
Avoid alcohol while taking Amypres C 12.5 mg/5 mg Tablet.
If you have diabetes, you will be asked to monitor your blood glucose level regularly as Amypres C 12.5 mg/5 mg Tablet may affect the levels of sugar in your blood.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Amypres C 12.5 mg/5 mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Q. Are there any important warnings associated with use of Amypres C 12.5 mg/5 mg Tablet?
During the first few months of treatment, Amypres C 12.5 mg/5 mg Tablet may increase suicidal thoughts or actions in some patients. Patients having mood or behavioral disorder have a high risk of developing suicidal thoughts and actions. You should pay close attention and report your doctor of any such behavior or mood changes. Make sure that you visit the doctor for the scheduled follow-up appointments.
Q. Can I stop taking Amypres C 12.5 mg/5 mg Tablet when my symptoms are relieved?
No, you should continue to take Amypres C 12.5 mg/5 mg Tablet, even if you feel well. If you stop Amypres C 12.5 mg/5 mg Tablet suddenly, serious withdrawal symptoms may occur. Consult your doctor if the symptoms are relieved, he might decrease your dose gradually.
Q. How to manage weight gain associated with the use of Amypres C 12.5 mg/5 mg Tablet?
There are reports which suggest that the use of Amypres C 12.5 mg/5 mg Tablet can cause weight gain. If you maintain good eating habits and exercise regularly, you might not gain any weight. An important to remember is that it is easier to prevent weight gain than losing increased weight.
Q. What are the instructions for storage and disposal of Amypres C 12.5 mg/5 mg Tablet?
Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.