Manufacturer: Sun Pharmaceutical Industries Ltd
Salt Composition : Anastrozole(1mg)
Strip of 5 Tablet
(Inclusive of all taxes)
Anabrez Tablet belong to a class of drug called aromatase inhibitors, which decreases the amount of estrogen in the body. It should be taken with or without food, but take it at the same time every day to get the most benefit. It should be taken as your doctor's advice. The dose and how often you take it depends on what you are taking it for. Your doctor will decide how much you need to improve your symptoms. Swallow the tablets whole with a drink of water. You should take this medicine for as long as it is prescribed for you.
The most common side effects of the medicine include hot flushes, nausea, rashes, joint pain, osteoporosis, and weakness. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them.
Before taking this medicine, tell your doctor if you are not gone through menopause and still having menstrual periods, or you have a problem with the liver or kidney. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Tell your doctor if you are pregnant or breastfeeding. Your doctor may perform some blood tests to check for vitamin D level or bone density.
Anastrozole structure and mechanism of action. Anastrozole is a nonsteroidal AI that inhibits the aromatase enzyme by binding reversibly to its heme ion. By inhibiting the activity of aromatase, anastrozole reduces the levels of E2, E1, and E1S both in the periphery and in the mammary tissue.
Anastrozole was rapidly absorbed orally (time to reach maximum concentration, 1 h) with a slow apparent clearance of 1.54 liters/h and a terminal half-life of 46.8 h. Testosterone/estradiol ratios increased significantly with concomitant increase in LH/FSH concentrations indicating aromatase blockade.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Anabrez
Hot flashes
Nausea
Osteoporosis
Skin rash
Weakness
high cholesterol.
a low supply of oxygen rich blood to the heart.
decreased calcification or density of bone.
pregnancy.
a patient who is producing milk and breastfeeding.
Anabrez Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
It is not known whether it is safe to consume alcohol with Anabrez Tablet. Please consult your doctor.
Anabrez Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Anastrozole is used to treat breast cancer in women after menopause. Some breast cancers are made to grow faster by a natural hormone called estrogen. Anastrozole decreases the amount of estrogen the body makes and helps to slow or reverse the growth of these breast cancers.
bazedoxifene/conjugated estrogens.
conjugated estrogens.
estradiol.
estrogens conjugated synthetic.
estrogens esterified.
estropipate.
ethinylestradiol.
tamoxifen.
Do not chew, crush or break it. Anabrez Tablet may be taken with or without food
Store below 30°C
If you miss a dose of Anabrez Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Anabrez Tablet is used for the treatment of hormone dependent breast cancer in postmenopausal women.
Take it at the same time everyday.
It may cause weakness and sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
Nausea may occur on starting treatment with this medicine but should go away with time. If nausea is bothersome, take it after meal.
Your doctor may regularly check your Vitamin D level and bone mineral density and suggest supplements, if needed.
Do not take Anabrez Tablet if you are pregnant or breastfeeding.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Anabrez Tablet may be taken with or without food, but it is better to take it at a fixed time.
Q. Does Anabrez Tablet cause weight gain?
Yes, Anabrez Tablet may cause weight gain, but it is not very common. There could be other reasons as well which can lead to weight gain such as menopause. However, if you gain weight while taking Anabrez Tablet, take low-calorie diet and exercise regularly. Consult your doctor or a nutritionist to help you lose weight.
Q. Does Anabrez Tablet cause hair loss?
Yes, Anabrez Tablet commonly affects the hair by making them thin which further leads to hair loss. However, it does not occur in everyone. Hair thinning probably occurs due to estrogen lowering effect of Anabrez Tablet. These effects are not permanent and may revert after some time. If it concerns you then talk to your doctor for another alternative medicine to avoid damage to hair.
Q. Why do bodybuilders use Anabrez Tablet?
Bodybuilders who take anabolic steroids for bodybuilding take Anabrez Tablet to reduce the production of estrogen which is a side effect of anabolic steroids. An increase in estrogen levels in bodybuilders may result in high pitched female voice, shrinking of the testicles or penis, and breast enlargement. In order to avoid such characteristics bodybuilders take Anabrez Tablet.
Q. Can Anabrez Tablet be taken at night?
Anabrez Tablet can be taken anytime of the day. Take it exactly as prescribed by your doctor. You can take it with or without food. Do not crush, break, or chew the tablet.
