Manufacturer: Albert David Ltd
Salt Composition : Thiocolchicoside(8mg), Aceclofenac(100mg), Paracetamol(325mg)
Strip of 10 Tablet
(Inclusive of all taxes)
Anaflam TH 8 Tablet is a combination medicine that helps in relieving muscular pain. It works by blocking the release of certain chemical messengers that cause pain, inflammation, and fever. This improves the movement of muscles and provides relief from pain and discomfort.
Anaflam TH 8 Tablet should be taken with food. This will prevent you from getting an upset stomach. The dose and duration will depend on the severity of your condition. You should keep taking the medicine even if you feel better until the doctor says it is alright to stop using it.
Using this medicine may cause few common side effects such as nausea, vomiting, heartburn, stomach pain, diarrhea, loss of appetite, and dryness in the mouth. If any of these side effects do not resolve with time or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the side effects. In general, you should try to use the smallest amount necessary to control your symptoms.
Before using the medicine, you should tell your doctor if you have any other medical conditions or disorders. To make sure it is safe, you should let your doctor know all the other medicines you are taking. Also, tell your doctor if you have any problems with your liver or kidneys. You should avoid the consumption of alcohol while on treatment with this medicine. Pregnant and breastfeeding women should consult their doctors first before using the medicine.
Thiocolchicoside (TCC) is used clinically for its muscle relaxant, anti-inflammatory, and analgesic properties, and it has been shown to interact with gamma-aminobutyric acid (GABA) type A receptors (GABAARs) and strychnine-sensitive glycine receptors in the rat central nervous system.
Aceclofenac is a non-steroidal agent with marked anti-inflammatory and analgesic properties. The mode of action of aceclofenac is largely based on the inhibition to prostaglandin synthesis. Aceclofenac is a potent inhibitor of the enzyme cyclo-oxygenase, which is involved in the production of prostaglandins
Paracetamol has a central analgesic effect that is mediated through activation of descending serotonergic pathways. Debate exists about its primary site of action, which may be inhibition of prostaglandin (PG) synthesis or through an active metabolite influencing cannabinoid receptors
Aceclofenac is a potent inhibitor of the enzyme cyclo-oxygenase, which is involved in the production of prostaglandins. After oral administration, aceclofenac is rapidly and completely absorbed as unchanged drug. Peak plasma concentrations are reached approximately 1.25 to 3.00 hours following ingestion.
Paracetamol is readily absorbed from the gastrointestinal tract with peak plasma concentrations occurring about 30 minutes to 2 hours after ingestion. It is metabolised in the liver (90-95%) and excreted in the urine mainly as the glucuronide and sulphate conjugates. Less than 5% is excreted as unchanged paracetamol.
Absorption - After IM administration, thiocolchicoside Cmax occur in 30 min and . reach values of 113 ng/mL after a 4 mg dose and 175 ng/mL after a 8 mg dose. The corresponding values of AUC are respectively 283 and 417 ng. h/mL
Nausea
Vomiting
Heartburn
Stomach pain
Diarrhea
Loss of appetite
Dryness in mouth
Thiocolchicoside must not be used - in patients hypersensitive to the active substance or to any of the excipients listed in section 6.1 - during the entire pregnancy period - during lactation - in women of childbearing potential not using contraception
ischaemic heart disease.
peripheral arterial disease.
cerebrovascular disease.
congestive heart failure
caloric undernutrition.
acute liver failure.
liver problems.
a condition where the body is unable to maintain adequate blood flow called shock.
acetaminophen overdose.
acute inflammation of the liver due to hepatitis C virus
Information regarding the use of Anaflam TH 8 Tablet during pregnancy is not available. Please consult your doctor.
It is not known whether it is safe to consume alcohol with Anaflam TH 8 Tablet. Please consult your doctor.
Information regarding the use of Anaflam TH 8 Tablet during breastfeeding is not available. Please consult your doctor.
Thiocolchicoside is a skeletal muscle-relaxant drug used in the treatment of orthopedic, traumatic and rheumatologic disorders 18. It is indicated as an adjuvant drug in the treatment of painful muscle contractures and is indicated in acute spinal pathology, for adults and adolescents 16 years of age and older
Aceclofenac+Paracetamol is used for pain relief. Aceclofenac + Paracetamol is a combination of two medicines: Aceclofenac and Paracetamol. These medicines work by blocking the action of chemical messengers responsible for pain, fever and inflammation
ACECLOFENAC+PARACETAMOL interact with cholesterol lowering drugs (cholestyramine), charcoal, medicine to stop vomiting (domperidone, metochlopramide), alcohol, anti HIV drug (zidovudine), blood thinner (warfarin), blood pressure lowering medicine, anti cancer or anti arthritis drug (methotrexate)
Buprenorphine Thiocolchicoside may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Bupropion The risk or severity of adverse effects can be increased when Bupropion is combined with Thiocolchicoside.
Swallow it as a whole. Do not chew, crush or break it. Anaflam TH 8 Tablet is to be taken with food.
Store below 30°C
If you miss a dose of Anaflam TH 8 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
You have been prescribed Anaflam TH 8 Tablet to relieve pain due to muscle spasm.
This medicine is most effective when taken along with proper rest and physical therapy.
Avoid consuming alcohol when taking Anaflam TH 8 Tablet as it may cause excessive drowsiness and increase the risk of liver damage.
Older adults may have increased drowsiness, confusion, and higher risk of falling as a result of taking Anaflam TH 8 Tablet.
Do not take it with any other medicine containing acetaminophen (drugs for pain/fever or cough-and-cold) without asking your doctor first.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Anaflam TH 8 Tablet is to be taken with food.
Q. Can the use of Anaflam TH 8 Tablet be stopped when my pain is relieved?
Anaflam TH 8 Tablet is usually used for short term and can be discontinued when the pain is relieved. However, Anaflam TH 8 Tablet should be continued if advised by the doctor.
Q. Are there any specific contraindications associated with the use of Anaflam TH 8 Tablet?
The use of Anaflam TH 8 Tablet is considered to be harmful for patients with known allergy to painkillers or any of the components or excipients of this medicine. The use of this medicine should preferably be avoided in patients with a history of stomach ulcers or in patients with active, recurrent stomach ulcer/bleeding. It should also be avoided in patients with a history of heart failure, high blood pressure, and liver or kidney disease.
Q. Can Anaflam TH 8 Tablet be taken with vitamin B-complex?
Yes, Anaflam TH 8 Tablet can be taken with vitamin B-complex preparations. While Anaflam TH 8 Tablet helps to relieve pain, vitamin B-complex can help to correct the vitamin deficiency that might be causing your symptoms.
Q. Can the use of Anaflam TH 8 Tablet cause damage to kidneys?
Yes, the long-term use of Anaflam TH 8 Tablet can cause damage to the kidneys. Normal kidneys produce a chemical called prostaglandins that protects them from damage. Use of painkillers lowers the levels of prostaglandins in the body leading to kidney damage on long-term use. Use of painkillers is not recommended to patients with underlying kidney disease.
