Andulfa 100mg (Injection)

Manufacturer: Intas Pharmaceuticals Ltd

Salt Composition : Anidulafungin(100mg)


Andulfa 100mg Injection is administered as an injection by a healthcare professional. Kindly do not self-administer. Do not skip any doses and finish the full course of treatment even if you feel better. Your liver function should be monitored regularly during treatment.

It may lead to a few common side effects like decreased potassium levels in the blood, nausea, diarrhea, headache, and vomiting. You may also notice some injection site reactions like pain, swelling, or redness. Inform your doctor if these side effects persist. Please consult your doctor if you are pregnant, planning to conceive, or breastfeeding.


Basic Information

Mechanism Of Action

Anidulafungin inhibits glucan synthase, an enzyme important in the formation of (1→3)-β-D-glucan, a major fungal cell wall component. Glucan synthase is not present in mammalian cells, so it is an attractive target for antifungal activity.


Pharmacokinets

This was expected based on the pharmacokinetic characteristics of anidulafungin. It is known that anidulafungin undergoes slow chemical degradation to produce a ring-opened peptide that lacks antifungal activity, which is subsequently converted to peptidic degradants and eliminated in feces.


Side Effects

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Andulfa

Decreased potassium level in blood

Nausea

Diarrhea

Headache

Vomiting

Fever

Anemia (low number of red blood cells)

Insomnia (difficulty in sleeping)

Indigestion

Injection site reactions (pain, swelling, redness)


Contra Indications

Hepatic disease. Use anidulafungin with caution in patients with hepatic disease. ...

Pregnancy. ...

Breast-feeding. ...

Neonates. ...

Hereditary fructose intolerance. ...

Polysorbate 80 hypersensitivity.


Pregnancy Related Information

Andulfa 100mg Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.


Product And Alcohol Interaction

It is not known whether it is safe to consume alcohol with Andulfa 100mg Injection. Please consult your doctor.


Breast Feeding Related Information

Andulfa 100mg Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.


Indications

indicated for the treatment of candidemia and the following Candida infections: intra-abdominal abscess and peritonitis in adults and pediatric patients 1 month of age and older see Clinical Studies  and Microbiology.


Interactions

Cyclosporine. ...

Voriconazole. ...

Tacrolimus. ...

Rifampin. ...

Amphotericin B Liposome for Injection.

Typical Dosage

Kindly do not self administer.

Storage Requirements

Store in a refrigerator (2 - 8°C). Do not freeze.


Effects Of Missed Dosage

If you miss a dose of Andulfa 100mg Injection, please consult your doctor.


Effects Of Overdose

Consult a doctor before taking any medicines.


Expert Advice

Andulfa 100mg Injection is given as a slow injection into the veins under the supervision of a doctor.

Do not skip any doses and finish the full course of treatment even if you feel better.

Your doctor may check your liver function regularly. Inform your doctor if you develop abdominal pain, loss of appetite, darkened urine or yellowing of the eyes or skin (jaundice).

Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.


How To Use

Your doctor or nurse will give you this medicine. Kindly do not self administer.


FAQs

Q. What is Andulfa 100mg Injection used for?

Andulfa 100mg Injection is used to treat fungal infection (Candida infections) of the blood or other internal organs.