Manufacturer: Bennet Pharmaceuticals Limited
Salt Composition : Ondansetron, Ranitidine
Vial of 2ml Injection
(Inclusive of all taxes)
Anset R Injection is given by your doctor or nurse. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your healthcare team know about all other medications you are taking as some may affect, or be affected by this medicine.
The most common side effects are diarrhea, constipation, headache, fatigue, muscle pain, dryness in mouth, and flushing of skin. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects. This medicine may cause dizziness and drowsiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine as it can worsen your dizziness.
Before you start taking this medicine it is important to inform your doctor if you are suffering from liver disease. Lifestyle modifications like having cold milk and avoiding hot tea, coffee, spicy food or chocolate can help you to get better results.
Ondansetron is a medication prescribed for the treatment and prevention of nausea and vomiting. It's a serotonin antagonist, meaning its mechanism of action is blocking the serotonin receptors in the CTZ.
Ranitidine is a competitive inhibitor of histamine H2-receptors. The reversible inhibition of H2-receptors in gastric parietal cells results in a reduction in both gastric acid volume and concentration.
Ondansetron is completely and rapidly absorbed from the gastrointestinal tract after oral administration, and does not accumulate with repeated oral administration. Owing to hepatic first-pass metabolism, its bioavailability is only about 60% compared with ondansetron administered by infusion over 15 minutes.
The pharmacokinetics of ranitidine has been described previously[9-11]. After oral administration 50% of ranitidine is absorbed, resulting in the peak serum concentration of 2 ± 3 h after dosing, followed by elimination with a half-life of 2.5 ± 3 h.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Anset R
Diarrhea
Constipation
Headache
Drowsiness
Fatigue
Muscle pain
Dryness in mouth
Flushing of skin
Contraindications. Ondansetron is contraindicated in patients: known to have hypersensitivity (e.g., anaphylaxis) to Ondansetron or any of the components of the formulation [see Adverse Reactions (6.2)] receiving concomitant apomorphine due to the risk of profound hypotension and loss of consciousness.
General Information. ...
H2-blocker hypersensitivity. ...
Gastric cancer. ...
Infection. ...
Hepatic disease. ...
Renal disease, renal failure, renal impairment. ...
Children, infants, neonates, premature neonates. ...
Pregnancy.
Anset R Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
It is unsafe to consume alcohol with Anset R Injection.
Anset R Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Ondansetron is indicated for the prevention of nausea and vomiting associated with: highly emetogenic cancer chemotherapy, including cisplatin greater than or equal to 50 mg/m 2. initial and repeat courses of moderately emetogenic cancer chemotherapy.
Benign gastric ulcer disease, short-term, and maintenance.
Duodenal ulcer disease, short-term, and maintenance.
Erosive esophagitis.
Hypersecretory conditions (e.g., Zollinger-Ellison, systemic mastocytosis, multiple endocrine adenoma syndrome)
Gastroesophageal reflux disease (GERD)
Some products that may interact with this drug are: apomorphine, tramadol. Many drugs besides ondansetron may affect the heart rhythm (QT prolongation), including dofetilide, pimozide, procainamide, amiodarone, quinidine, sotalol, macrolide antibiotics (such as erythromycin), among others.
atazanavir.
dasatinib.
delavirdine.
erlotinib.
itraconazole.
ivacaftor.
ketoconazole.
mesalamine.
Kindly do not self administer.
Store below 30°C
If you miss a dose of Anset R Injection, please consult your doctor.
Consult a doctor before taking any medicines.
Anset R Injection is administered to give relief from nausea, vomiting as well as acidity, heartburn and other discomfort associated with acid reflux.
Avoid taking soft drinks, citrus fruits like orange and lemon, which can irritate the stomach and increase acid secretion.
Incorporate the folowing lifestyle changes in order to prevent acidity:
Make sure you eat regular meals and drink plenty of water.
Avoid spicy and fatty fried food.
Lose weight if you are obese.
If you are a smoker, consider giving up.
Don't drink too much alcohol.
Do not go to bed immediately after taking a meal. Sit in a relaxed position for sometimes for better digestion.
Your doctor or nurse will give you this medicine. Kindly do not self administer.
