Manufacturer: Sanofi India Ltd
Salt Composition : Insulin Glulisine(100IU)
Apidra 100IU/ml Solution for Injection is normally prescribed along with a long-acting type of insulin or other diabetes medicines. Your doctor or nurse will teach you the correct way of injecting it under the skin. It should be taken 15 minutes before a meal or within 20 minutes after starting a meal. Do not stop taking it unless your doctor tells you to. It is only part of a treatment program that should also include a healthy diet, regular exercise, and weight reduction as advised by your doctor.
Check your blood sugar levels regularly, keep track of your results and share them with your doctor. This is very important to work out the correct dose of the medicine for you.
The most common side effects of this medicine include hypoglycemia, allergic reactions, injection site reactions, lipodystrophy, itching, and rash. To prevent these, it is important to always inject the correct dose of medicine, have regular meals (do not skip), and monitor your blood sugar levels regularly.
Do not use this medicine when you have low blood sugar levels (hypoglycemia). Tell your doctor if you have ever had kidney, liver, or heart problems before starting treatment. Pregnant or breastfeeding women should consult their doctor before using it.
Regulation of glucose metabolism is the primary activity of insulins and insulin analogs, including insulin glulisine. Insulins lower blood glucose by stimulating peripheral glucose uptake by skeletal muscle and fat, and by inhibiting hepatic glucose production.
Pharmacokinetic studies with insulin glulisine have shown an absorption profile with a peak insulin concentration approximately twice that of regular human insulin, which is reached in approximately half the time.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Apidra
Hypoglycemia (low blood glucose level)
Nasopharyngitis (inflammation of the throat and nasal passages)
Upper respiratory tract infection
General Information. ...
Diarrhea, fever, infection, surgery, thyroid disease, trauma, vomiting. ...
Hepatic disease, renal failure, renal impairment. ...
Coma, diabetic ketoacidosis, hyperosmolar hyperglycemic state (HHS) ...
Continuous subcutaneous insulin infusion (CSII) administration. ...
Hypoglycemia.
Apidra 100IU/ml Solution for Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
It is unsafe to consume alcohol with Apidra 100IU/ml Solution for Injection.
Information regarding the use of Apidra 100IU/ml Solution for Injection during breastfeeding is not available. Please consult your doctor.
Insulin glulisine is indicated to improve glycemic control in adults and pediatric patients with diabetes mellitus. Insulin is a natural hormone produced by beta cells of the pancreas. In non-diabetic individuals, a basal level of insulin is supplemented with insulin spikes following meals.
There are 3 disease interactions with insulin glulisine which include: renal/liver disease. hypokalemia. hypoglycemia.
Store in a refrigerator (2 - 8°C). Do not freeze.
If you have missed a dose of Apidra 100IU/ml Solution for Injection, your blood sugar level may become too high (hyperglycemia). Check your blood sugar and then take the next dose accordingly.
Consult a doctor before taking any medicines.
Apidra 100IU/ml Solution for Injection helps to control blood sugar level and avoid long-term complications.
You should continue to exercise regularly, eat a healthy diet and take your other diabetes medicines along with Apidra 100IU/ml Solution for Injection.
Take it 15 minutes before a meal or within 20 minutes after starting a meal.
Injection sites must be rotated to prevent hard lumps from developing at one site.
Injection below the skin of the abdomen results in faster absorption than other injection sites.
Do not use it if the preparation is no longer clear and colorless or if it contains particles.
Hypoglycemia (low blood sugar level) is a common side effect. Monitor your blood sugar level regularly.
Always carry some sugary food or fruit juice with you in case you experience hypoglycemia symptoms such as cold sweats, cool pale skin, tremors, weakness, and anxiety.
Opened vials/cartridges stay good at room temperature for up to 4 weeks, while unopened vials must be placed in the refrigerator (2°C–8°C).
Your doctor or nurse will guide you how to use this medicine.
Q. I am taking pioglitazone for diabetes. Can I take Apidra 100IU/ml Solution for Injection with it?
You have to be extra careful if you are planning to take both pioglitazone and Apidra 100IU/ml Solution for Injection. Consult your doctor first before taking any other medicine. The doctor will suggest if you can safely take Apidra with pioglitazone and if you would need regular follow-up. This is because Pioglitazone can cause fluid retention in your body, especially when used in combination with insulin. You may develop symptoms of heart failure like edema, swelling of hands and feet, weight gain, breathlessness, etc. Also if you already have heart failure, it may get aggravated.
Q. I started using Apidra 100IU/ml Solution for Injection recently and was told to not inject into the same spot over and over again. Why?
It is correct that you should not use the same spot again, as it can cause changes in the fatty tissue just under the skin. It can either cause lipodystrophy or lipohypertrophy. Lipodystrophy means abnormal changes in the distribution of body fat. It includes lipohypertrophy (thickening of adipose tissue) and lipoatrophy (thinning of adipose tissue), and may affect insulin absorption. Rotate insulin injection or infusion sites within the same region to reduce the risk of lipodystrophy.
Q. What if I accidentally inject Apidra 100IU/ml Solution for Injection into a muscle?
Apidra 100IU/ml Solution for Injection contains a fast-acting insulin. Injecting Apidra into a muscle would make its absorption even more rapid. As a result, the chance of having a serious episode of hypoglycemia or low blood sugar would increase. Therefore, you should inject the insulin just beneath the skin by pinching up some skin and fat.<br>
Q. I have been taking metoprolol for high blood pressure for a long time. Do I need to be careful about anything if I have started glulisine now?
Yes, you need to be careful because symptoms of low blood sugar (hypoglycemia) like increased heart rate may not be noticed by you. Keep a regular check on your blood sugar and consult your doctor if the problem persists.
