Manufacturer: Natco Pharma Ltd
Salt Composition : Apixaban(2.5mg)
Apigat 2.5 tablet is an anticoagulant medicine or a blood thinner that contains apixaban as an active ingredient. It reduces the risk of stroke and blood clots. Apigat 2.5 tablet must be used under mdical prescription, and for the duration, it is prescribed. You should complete the entire treatment with the medicine and not stop it mid-way on your own without consulting the doctor.
Apixaban inhibits free and clot-bound FXa, and prothrombinase activity. Apixaban has no direct effect on platelet aggregation, but indirectly inhibits platelet aggregation induced by thrombin. By inhibiting FXa, apixaban decreases thrombin generation and thrombus development.
The pharmacokinetic properties of apixaban have been described in detail. In healthy male volunteers, apixaban was rapidly absorbed after oral administration, with a time to maximum plasma apixaban concentration of about 1 hour. The elimination half-life for apixaban in healthy subjects is approximately 12 hours.
Nausea
Bruising or swelling
Nosebleed
Anaemia
If you are allergic to apixaban or other ingredients of Apigat 2.5 tablet.
If you take medicines like warfarin, heparin to prevent blood clotting.
If you suffer from a bleeding disorder.
If you suffer from a liver disease associated with an increased risk of bleeding.
If you have a disease in an organ of the body that may increase the risk of bleeding like recent bleeding in your brain on spinal injury, active or a recent ulcer of the stomach or intestine.
Since there is limited safety information available for pregnant women, avoid during pregnancy. If you get pregnant while on treatment, immediately contact the doctor. Consult the doctor if you are pregnant or think you may be or are planning a pregnancy, before starting the medicine.
Avoid consuming alcohol in excess while taking Apigat 2.5 tablet as it can make more likely to bleed.
There is limited safety data available about the use of this medicine in breastfeeding mothers. Hence, it is very important to consult your doctor before using this medicine while breastfeeding.
Apixaban is indicated for reducing the risk of stroke and systemic embolism in patients who have nonvalvular atrial fibrillation, prophylaxis of deep vein thrombosis(DVT) leading to pulmonary embolism(PE) in patients after a hip or knee replacement surgery, and treatment of DVT and PE to reduce the risk of recurrence
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Swallow as a whole with a glass of water, do not cut, break or chew the medicine. Take with or without food.
Store below 30°C
If you missed taking a dose of Apigat 2.5 tablet, take it as soon as you remember. If it's time for the next dose, skip the missed dose and continue with the regular dose schedule. Avoid taking a double dose of medicine to compensate for the missed one.
Overdose of Apigat 2.5 tablets increase the risk of bleeding. If you think you have taken an excessive dose of the medicine, contact the doctor immediately or visit the nearest hospital.
Some medicines affect the way Apigat 2.5 tablet works, or the medicine itself reduces the effectiveness of other medicines taken at the same time.
Inform the physician about the medicines, supplements, or herbals you are taking or might take to avoid possible interaction.
Apigat 2.5 tablet is not recommended for patients being treated with antifungal medicines like ketoconazole, itraconazole, voriconazole and posaconazole, anti-HIV medicines like ritonavir, anti-tuberculosis medicine like rifampicin, medicines used to treat epilepsy like phenytoin, carbamazepine, phenobarbital, Antidepressants like paroxetine, fluoxetine, diazepam as it may affect the efficacy of Apigat 2.5 tablet.
Concomitant use of anticoagulants like warfarin and pain killer medicines like acetylsalicylic acid, aspirin or other strong painkillers, increases the risk of bleeding.
Other medicines like diltiazem, verapamil (used to treat blood pressure), enoxaparin, clopidogrel (used as an anticoagulant) must be used with caution along with Apigat 2.5 tablet.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Apigat 2.5 tablet is to be taken with food.
Q: Can I stop taking Apigat 2.5 on my own?
A: You should not stop taking Apigat 2.5 tablets until the doctor tells you to. It causes an increased risk of problems like heart stroke, clots in the lungs or legs etc.
Q: Is it safe to do piercing or tattooing while taking the medicine?
A: No, avoid doing such things during the treatment with Apigat 2.5 tablet. It leads to an increased risk of bleeding and infection. If you want to do, consult with the doctor once, whether you need to take additional medicines.
Q: What is Apigat 2.5 used for?
A: Apigat 2.5 is used for the treatment and prevention of blood clots. It is also used to reduce the risk of stroke and blood clots in patients suffering from irregular heartbeat (arrhythmia) after hip or knee replacement surgery.
