Manufacturer: Natco Pharma Ltd
Salt Composition : Apixaban(5mg)
This medicine is used to reduce the risk of blood clots formation in heart of the patients with atrial fibrillation (an abnormal heartbeat) and other risk factors for stroke. These blood clots might break and travel to the brain, leading to a stroke or to other organs and prevent their normal blood flow (systemic embolism).
APIGAT 2.5MG can also be used to treat other blood clotting conditions like deep vein thrombosis (blood clots in veins of legs) and pulmonary embolism (blood clot in blood vessels of lungs), and also prevents its recurrence in patients with or without hip or knee replacement operations. This medicine can be taken with or without food.
The most common side effects of taking this medicine are bleeding in eyes, nose, gums, stomach, rectum or vagina. Do not take this medicine, if you have any bleeding disorders. Discuss the risks and benefits with your doctor. Before taking this medicine inform your doctor if you are pregnant, breastfeeding or having any serious kidney or liver disease. This medicine is not recommended for use in children and adolescents under 18 years of age. Consult your doctor before taking.
Apixaban is a highly selective, orally bioavailable, and reversible direct inhibitor of free and clot-bound factor Xa. Factor Xa catalyzes the conversion of prothrombin to thrombin, the final enzyme in the coagulation cascade that is responsible for fibrin clot formation.
The pharmacokinetic properties of apixaban have been described in detail. In healthy male volunteers, apixaban was rapidly absorbed after oral administration, with a time to maximum plasma apixaban concentration of about 1 hour. The elimination half-life for apixaban in healthy subjects is approximately 12 hours.
Bleeding in your eyes, stomach, rectum or vagina
Blood in the urine
Bleeding from nose or gums
Bruising and swelling
Anemia, tiredness or paleness
Low blood pressure
Nausea (feeling sick)
Skin rash
Reduced platelet count in blood
operation on the spine.
eye surgery.
an increased risk of bleeding.
decreased blood platelets.
a hemorrhage in the brain.
bleeding.
decreased kidney function.
a patient who is producing milk and breastfeeding.
APIGAT 2.5MG is not recommended for use in pregnant women unless necessary. Discuss the risks and benefits with your doctor.
Avoid consumption of alcohol while taking this medicine.
APIGAT 2.5MG is not recommended for use in breastfeeding women unless necessary. Discuss the risks and benefits with your doctor.
Apixaban is indicated for reducing the risk of stroke and systemic embolism in patients who have nonvalvular atrial fibrillation, prophylaxis of deep vein thrombosis(DVT) leading to pulmonary embolism(PE) in patients after a hip or knee replacement surgery, and treatment of DVT and PE to reduce the risk of recurrence
carbamazepine.
defibrotide.
dexamethasone.
fosphenytoin.
phenytoin.
prothrombin complex concentrate, human.
rifabutin.
rifampin.
It can be taken with or without food. Your doctor will decide the correct dose for you depending upon your condition
Store below 30°C
If you miss a dose of APIGAT 2.5mg Tablet 30's, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
This medicine is used to reduce the risk of blood clots formation in heart of the patients with atrial fibrillation (an abnormal heartbeat) and other risk factors for stroke. These blood clots might break and travel to the brain, leading to a stroke or to other organs and prevent their normal blood flow (systemic embolism).
APIGAT 2.5MG can also be used to treat other blood clotting conditions like deep vein thrombosis (blood clots in veins of legs) and pulmonary embolism (blood clot in blood vessels of lungs), and also prevents its recurrence in patients with or without hip or knee replacement operations. This medicine can be taken with or without food.
Take this medicine as directed by your physician. It can be taken with or without food. Your doctor will decide the correct dose for you depending upon your condition. Swallow the medicine as whole with a glass of water.
Q Can APIGAT 2.5MG cause low platelet count?
Yes. This medicine may cause reduced platelet count in blood in some individuals. Consult your doctor for advice.
Q Should patients stop taking APIGAT 2.5MG if they are going to have a dental or medical procedure?
This medicine may need to be stopped for one or two days before any planned surgery, dental or medical procedure. Follow the instructions given by the physician. You should not stop taking this medicine without first talking to your doctor or dentist.
Q When and how do I take this medicine?
Always take this medicine as instructed by your doctor. If you do not take this medicine regularly there is a risk of increase in clot formation.