Manufacturer: Glenmark Pharmaceuticals Ltd
Salt Composition : Aprepitant(150mg)
Aprecap 150mg Injection is a prescription medicine used to prevent nausea and vomiting caused by chemotherapy. It is also used in the prevention of postoperative nausea and vomiting in adults.
Aprecap 150mg Injection is given by your doctor or nurse. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early, your symptoms may come back, and your condition may worsen. Let your doctor know about all other medications you are taking as some may affect, or be affected by this medicine.
The most common side effects are headache, hiccups, loss of appetite, fatigue, and constipation. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects. This medicine may also cause diarrhea, so it is beneficial to drink plenty of fluids while taking this medicine as it may help to prevent dehydration. It may also cause dizziness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine as it can worsen your sleepiness.
Before taking this medicine, you should tell your doctor if you are pregnant, planning a pregnancy, or breastfeeding. You should tell your doctor if you have any kidney or liver diseases so that your doctor can prescribe a suitable dose for you.
Aprepitant is in a class of medications called antiemetics. It works by blocking the action of neurokinin, a natural substance in the brain that causes nausea and vomiting
The pharmacokinetics of aprepitant are non-linear across the clinical dose range. In healthy young adults, the increase in AUC0-∞ was 26% greater than dose proportional between 80-mg and 125-mg single doses administered in the fed state.
Headache
Dizziness
Hiccup
Loss of appetite
Fatigue
Constipation
Diarrhea
Aprepitant is contraindicated in patients: who are hypersensitive to any component of the product. Hypersensitivity reactions including anaphylactic reactions have been reported [see Adverse Reactions (6.2)]. taking pimozide
Aprecap 150mg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
It is not known whether it is safe to consume alcohol with Aprecap 150mg Injection. Please consult your doctor.
Aprecap 150mg Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Aprepitant, an antiemetic, is a substance P/neurokinin 1 (NK1) receptor antagonist which, in combination with other antiemetic agents, is indicated for the prevention of acute and delayed nausea and vomiting associated with initial and repeat courses of highly emetogenic cancer chemotherapy
Concurrent administration of aprepitant and the following drugs may lead to adverse events: alcohol (impaired cognition), ifosfamide (neurotoxicity), oxycodone (decreased respiratory rate, increased feeling of a 'high'), quetiapine (somnolence), SSRI/SNRIs (vomiting) and warfarin (INR changes).
Your doctor or nurse will give you this medicine.
Store in a refrigerator (2 - 8°C). Do not freeze.
If you miss a dose of Aprecap 150mg Injection, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Aprecap 150mg Injection helps prevent nausea and vomiting caused by certain chemotherapy medicines.
It will not help if you already have nausea and vomiting.
Do not use it continuously for a long time.
It is recommended to take Aprecap 150mg Injection 1 hour before chemotherapy treatment (Day 1) and in the morning on Days 2 and 3.
Aprecap 150mg Injection may be unsafe to use if you are pregnant, planning a pregnancy, or breastfeeding.
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Q. Does Aprecap 150mg Injection help treat nausea and vomiting?
No, this medicine will not treat nausea or vomiting that has already started. Aprecap 150mg Injection is used with other medications to help prevent nausea and vomiting caused by cancer drug treatment (chemotherapy). It prevents the feeling of sickness by blocking the body's natural substances that cause nausea and vomiting.
Q. What are some of the serious side-effects of Aprecap 150mg Injection?
Some of the serious side-effects of this medicine are rash, itching, skin peeling or blisters, difficulty breathing or swallowing.
Q. Does Aprecap 150mg Injection reduce the effectiveness of contraceptives?
This medicine can make hormonal birth control less effective, including birth control pills, injections, implants, skin patches, and vaginal rings. To prevent pregnancy while using Aprecap 150mg Injection, use a barrier form of birth control like condom, diaphragm, or cervical cap. Keep using the barrier form of birth control for 1 month after your last dose of aprepitant.
Q. Is Aprecap 150mg Injection given before or after chemotherapy?
Aprecap 150mg Injection is administered 1 hour before your chemotherapy on days 1, 2, and 3 of your treatment.
