Manufacturer: Intas Pharmaceuticals Ltd
Salt Composition : Aprepitant(125mg)
Aprepep 125mg Capsule is a prescription medicine used to prevent nausea and vomiting caused by chemotherapy. It is also used in the prevention of postoperative nausea and vomiting in adults.
Aprepep 125mg Capsule is taken with or without food in a dose and duration as advised by the doctor. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your doctor know about all other medications you are taking as some may affect, or be affected by this medicine.
The most common side effects are headache, hiccups, loss of appetite, fatigue, and constipation. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects. This medicine may cause diarrhea, so it is beneficial to drink plenty of fluids while taking this medicine as it may help to prevent dehydration. It may also cause dizziness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine as it can worsen your sleepiness.
Before taking this medicine, you should tell your doctor if you are pregnant, planning a pregnancy, or breastfeeding. You should tell your doctor if you have any kidney or liver diseases so that your doctor can prescribe a suitable dose for you.
Aprepitant is in a class of medications called antiemetics. It works by blocking the action of neurokinin, a natural substance in the brain that causes nausea and vomiting
The pharmacokinetics of aprepitant are non-linear across the clinical dose range. In healthy young adults, the increase in AUC0-∞ was 26% greater than dose proportional between 80-mg and 125-mg single doses administered in the fed state.
Headache
Dizziness
Hiccup
Loss of appetite
Fatigue
Constipation
Diarrhea
Aprepitant is contraindicated in patients: who are hypersensitive to any component of the product. Hypersensitivity reactions including anaphylactic reactions have been reported [see Adverse Reactions (6.2)]. taking pimozide
Aprepep 125mg Capsule may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
It is not known whether it is safe to consume alcohol with Aprepep 125mg Capsule. Please consult your doctor.
Aprepep 125mg Capsule is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Aprepitant, an antiemetic, is a substance P/neurokinin 1 (NK1) receptor antagonist which, in combination with other antiemetic agents, is indicated for the prevention of acute and delayed nausea and vomiting associated with initial and repeat courses of highly emetogenic cancer chemotherapy
Concurrent administration of aprepitant and the following drugs may lead to adverse events: alcohol (impaired cognition), ifosfamide (neurotoxicity), oxycodone (decreased respiratory rate, increased feeling of a 'high'), quetiapine (somnolence), SSRI/SNRIs (vomiting) and warfarin (INR changes).
Aprepep 125mg Capsule may be taken with or without food, but it is better to take it at a fixed time.
Store below 30°C
If you miss a dose of Aprepep 125mg Capsule, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines
Aprepep 125mg Capsule helps prevent nausea and vomiting caused by certain chemotherapy medicines.
It will not help if you already have nausea and vomiting.
Do not use it continuously for a long time.
It is recommended to take Aprepep 125mg Capsule 1 hour before chemotherapy treatment (Day 1) and in the morning on Days 2 and 3.
It may damage sperms and may harm the baby if used during pregnancy or breastfeeding.
Take this medicine in the dose and duration as advised by your doctor. Aprepep 125mg Capsule may be taken with or without food, but it is better to take it at a fixed time.
Q. What are Aprepep 125mg Capsule capsules/ what is Aprepep 125mg Capsule used for?
Aprepep 125mg Capsule is used in adults in combination with other medicines to prevent nausea and vomiting caused by chemotherapy (cancer treatment) or in some cases after a surgery
Q. How does Aprepep 125mg Capsule work?
Aprepep 125mg Capsule is an antiemetic that works by blocking the action of neurokinin, a natural substance in the brain that causes nausea and vomiting.
