Manufacturer: Glenmark Pharmaceuticals Ltd
Salt Composition : Apremilast(30mg)
Strip of 10 Tablet
(Inclusive of all taxes)
Aprezo Tablet can be taken with or without food. Take it regularly and do not stop taking the medicine even if you get better until that doctor tells you it is alright to stop. You may need to monitor your weight regularly while taking the medicine as it may cause weight loss.
Using this medicine may cause few common side effects such as nausea, diarrhea, and vomiting. If these side effects persist or get worse, let your doctor know. Your doctor may help with ways to reduce or prevent these symptoms by prescribing you an alternative medicine or by adjusting the dose.
To make sure the medicine is safe for you, before taking this medicine, let your doctor know all the other medicines you are taking. If you are pregnant or breastfeeding, consult your doctor first before taking this medicine.
Aprezo Tablet is a phosphodiesterase 4 (PDE4) inhibitors. It works by blocking the action of certain chemical messengers that are responsible for inflammation associated with psoriatic arthritis and psoriasis, and thereby reduces the signs and symptoms of these conditions.
Apremilast is a small-molecule inhibitor of PDE4, an enzyme that breaks down cyclic adenosine monophosphate (cAMP). In inflammatory cells, PDE4 is the dominant enzyme responsible for this reaction.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Aprezo
Diarrhea
Nausea
Vomiting
depression.
weight loss.
chronic kidney disease stage 4 (severe)
chronic kidney disease stage 5 (failure)
Aprezo Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Caution is advised when consuming alcohol with Aprezo Tablet. Please consult your doctor.
Information regarding the use of Aprezo Tablet during breastfeeding is not available. Please consult your doctor.
Psoriatic arthritis.
Plaque psoriasis.
Oral ulcers associated with Behcet disease.
Activated Charcoal (charcoal)
Advair Diskus (fluticasone / salmeterol)
Alcohol (contained in alcoholic beverages) (ethanol)
Aspirin Low Strength (aspirin)
Bactrim DS (sulfamethoxazole / trimethoprim)
Calcium 600 D (calcium / vitamin d)
Cymbalta (duloxetine)
D3 (cholecalciferol)
Do not chew, crush or break it. Aprezo Tablet may be taken with or without food, but it is better to take it at a fixed time.
Store below 30°C
If you miss a dose of Aprezo Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Aprezo Tablet is a well-tolerated medicine. Mild stomach upset may occur early during the treatment.
Monitor your weight regularly as Aprezo Tablet may cause weight loss.
Your doctor will gradually increase the dose from day 1 to day 6 of treatment, after which it may be kept constant.
Tell your doctor immediately if you experience new or worsened depression, suicidal thoughts, other mood changes or unexplained weight loss.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Aprezo Tablet may be taken with or without food, but it is better to take it at a fixed time.
Q. Is Aprezo Tablet an immunosuppressant?
No, Aprezo Tablet is not an immunosuppressant. It belongs to a class of medicines known as phosphodiesterase 4 inhibitors (PDE4) which work by blocking the activity of PDE4. PDE4 is found in inflammatory cells and blocking it helps in reducing the molecules responsible for inflammation.
Q. How long does it take for Aprezo Tablet to work?
Aprezo Tablet is used to treat plaque psoriasis (red, scaly, thick, itchy, painful patches on skin) and psoriatic arthritis (a condition that causes joint pain and swelling). It is a long-term treatment and may take about 16 weeks to show an improvement.
Q. Can Aprezo Tablet cause depression?
Yes, Aprezo Tablet may cause depression as a side effect. The patient may also develop suicidal thoughts. It should be avoided in patients with a history of depression. In case you develop any of these symptoms, consult your doctor immediately or ask your friends or relatives to help seek medical advice.
Q. Does Aprezo Tablet cause weight reduction?
Yes, Aprezo Tablet may cause a decrease in appetite which may further cause weight loss. You should monitor your weight regularly while on treatment with Aprezo Tablet. In case of significant weight loss, consult your doctor and consider stopping Aprezo Tablet.
