Manufacturer: Macleods Pharmaceuticals Pvt Ltd
Salt Composition : Epalrestat(50mg)
Strip of 10 Tablet
(Inclusive of all taxes)
Aristat 50mg Tablet belongs to a group of medicines known as Aldose reductase inhibitors. It can be taken with or without food but you should try to take it at the same time every day. This will help you to remember to take it. The dose and how often you need it will be decided by your doctor so that you get the right amount to control your symptoms. It may take up to 3 months to get the full benefits of this medicine, but you should keep taking it regularly. Do not stop taking it without asking your doctor, otherwise, your condition may worsen.
This medicine is only part of a treatment program that should also include a healthy diet, regular exercise, and weight reduction as advised by your doctor. You should also continue taking other medicines prescribed by your doctor for blood sugar control. Keeping your blood sugar levels under control will help this medication work better.
The most common side effects of this medicine include nausea, vomiting, and abnormalities in liver function tests (increased liver enzymes). Most side effects are temporary and improve as your body gets used to the medicine. Please consult your doctor if any of these bother you or do not go away.
Before taking this medicine, let your doctor know if you have any kidney or liver problems. Pregnant or breastfeeding women should also consult their doctor before taking this medicine. Avoid any alcohol intake while taking it as this may increase the risk of developing some side effects.
Conclusions: Our data suggested that epalrestat inhibited high glucose-mediated neutrophil-endothelial cell adhesion and expression of endothelial adhesion molecules not only through inhibition of a PKC-dependent pathway, but also through increased endothelial NO production.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Aristat
Nausea
Vomiting
Abnormal liver function
Epalrestat is contraindicated in patient with allergies and severe liver disease.
Information regarding the use of Aristat 50mg Tablet during pregnancy is not available. Please consult your doctor.
It is unsafe to consume alcohol with Aristat 50mg Tablet.
Information regarding the use of Aristat 50mg Tablet during breastfeeding is not available. Please consult your doctor.
EPALRESTAT is used for the management of diabetic neuropathy. EPALRESTAT works by inhibiting aldose reductase enzyme which catalyses the conversion of glucose to sorbitol. Accumulation of sorbitol occurs due to hyperglycaemia in patients who have diabetes which leads to nerve pain.
Drug-Drug Interactions: No interactions found/established. Drug-Food Interactions: No interactions found/established. Drug-Disease Interaction: EPALRESTAT might have interaction with liver and kidney dysfunction.
Do not chew, crush or break it. Aristat 50mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Store below 30°C
If you miss a dose of Aristat 50mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Adherence to antidiabetic therapy can delay the onset of or prevent diabetic nerve disease.
If you have existing diabetic nerve disease, wear proper footwear and examine your feet every day to detect lesions early.
If you have a foot injury or open wound, avoid engaging in weight-bearing activities.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Aristat 50mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
