Manufacturer: RKG Pharma
Salt Composition : Pimozide(2mg)
Strip of 10 Tablet
(Inclusive of all taxes)
Arkazid 2mg Tablet may be taken with or without food, preferably at the same time each day. Take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor and if you have missed a dose, take it as soon as you remember it. Do not skip any doses and finish the full course of treatment even if you feel better. This medication mustn't be stopped suddenly without talking to your doctor as it may worsen your symptoms.
Some common side effects of this medicine include dry mouth, abnormality of voluntary movements, urinary retention, constipation, and muscle rigidity. Initially, this medicine may cause a sudden drop in blood pressure when you change positions, rise slowly if you have been sitting or lying down. It may also cause dizziness and sleepiness, do not drive or do anything that requires mental focus until you know how this medicine affects you.
Arkazid 2mg Tablet is a typical antipsychotic. It works by blocking the action of dopamine, a chemical messenger in the brain that affects thoughts and mood.
Based on the pharmacokinetic and metabolic profile, pimozide appears to undergo significant first pass Page 2 2 metabolism. Peak serum levels occur generally six to eight hours (range 4-12 hours) after dosing. Pimozide is extensively metabolized, primarily by N-dealkylation in the liver.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Arkazid
Sleepiness
Orthostatic hypotension (sudden lowering of blood pressure on standing)
Dryness in mouth
Abnormality of voluntary movements
Weight gain
Increased prolactin level in blood
Urinary retention
Constipation
Abnormal vision
Tremors
breast cancer
a high prolactin level
low amount of magnesium in the blood
low amount of potassium in the blood
very low levels of granulocytes, a type of white blood cell
low levels of white blood cells
low levels of a type of white blood cell called neutrophils
chronic muscle twitches or movements
a type of movement disorder called parkinsonism
tardive dyskinesia, a disorder characterized by involuntary movements of the face, mouth and tongue
extrapyramidal disease, a type of movement disorder
neuroleptic malignant syndrome, a reaction characterized by fever, muscle rigidity and confusion
glaucoma, an increased pressure in the eye
torsades de pointes, a type of abnormal heart rhythm
prolonged QT interval on EKG
abnormal heart rhythm
ventricular arrhythmias, a type of abnormal heart rhythm
abnormal EKG with QT changes from birth
liver problems
decreased kidney function
enlarged prostate
coma
seizures
an inability to completely empty the bladder
impairment of central nervous system due to medication
dementia in an elderly person
CYP2D6 poor metabolizer
Arkazid 2mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Arkazid 2mg Tablet may cause excessive drowsiness with alcohol.
Arkazid 2mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Use with caution
Below 9years: Contraindicated
ORAP (pimozide) is indicated for the suppression of motor and phonic tics in patients with Tourette's Disorder who have failed to respond satisfactorily to standard treatment.
dementia
CNS depression/coma
previous neuroleptic malignant syndrome (NMS)
seizure disorders
acute alcohol intoxication
CNS depression
NMS
tardive dyskinesia
pituitary tumors
QT interval prolongation
tics
seizure
hyperprolactinemia/breast cancer
neutropenia
anticholinergic effects
hyperprolactinemia
parkinsonism
renal/liver disease
Do not chew, crush or break it. Arkazid 2mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Store below 30°C
If you miss a dose of Arkazid 2mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Take it at the same time every day to help you remember to take it.
Get regular blood tests to monitor the levels of electrolytes (salts such as potassium and magnesium) in your blood as suggested by your doctor.
Regularly get your heart function monitored as suggested by your doctor.
It may increase your weight, blood sugar and cholesterol. Eat healthy, exercise regularly and monitor your blood levels regularly.
Use caution while driving or doing anything that requires concentration as Arkazid 2mg Tablet can cause dizziness and sleepiness.
Inform your doctor if you experience symptoms such as high fever, sweating, muscle stiffness, and faster breathing. These may be due to a rare side effect known as a neuroleptic malignant syndrome.
Do not stop taking Arkazid 2mg Tablet without talking to your doctor first as it may cause a worsening of symptoms.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Arkazid 2mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Q. How does Arkazid 2mg Tablet work?
Arkazid 2mg Tablet is an antipsychotic that acts by altering the effect of a chemical (dopamine), thereby, decreasing abnormal activity in the brain.
