Arpimune O 100mg Capsule (5'S)

Manufacturer: RPG Life Sciences Ltd

Salt Composition : Ciclosporin(100mg)

Prescription
Prescription Required: Consult the Doctor & Get Your ePrescription

The amount of Arpimune-O 100mg Capsule you take depends on your weight, medical condition, and what you are being treated for. Your doctor will plan the correct dose for you. Do not change the dose without talking to your doctor. It can be taken with or without food. It is better to take it, in the same way, and at the same time every day to get the maximum benefit. Keep taking it for as long as you have been told to, even if you feel well. Stopping treatment may increase the risk of your transplanted organ being rejected.

The most common side effects of this medicine include headache, unusual growth of facial or body hair, high blood pressure, diarrhea, and shaking or tremors. Because it lowers your immune system, you may also catch more infections than usual. Tell your doctor straight away if you develop an infection. For the same reason, you may be more at risk of developing some cancers, particularly of the skin. You should limit your exposure to sunlight.

Before taking this medicine you should tell your doctor if you have liver or kidney problems, high blood pressure, gout (increased uric acid levels in the blood), or epilepsy. Also, tell your doctor about all other medicines you are taking as they may affect the working of the medicine. This medicine should only be used in pregnancy if it is clearly needed. However, it is not recommended while breastfeeding. You will have frequent medical tests while taking this medicine to check your blood pressure, liver and kidney function, and mineral levels. The results of tests may lead to changes in your dose.


Basic Information

Mechanism Of Action

Cyclosporine is a potent immunomodulatory agent with an increasing number of clinical applications. Its major mode of action is inhibition of the production of cytokines involved in the regulation of T-cell activation. In particular, cyclosporine inhibits the transcription of interleukin 2.


Pharmacokinets

Cyclosporine is extensively distributed in peripheral tissues. Its volume of distribution is 3 to 5 L/kg. Cyclosporine distribution in the blood is approximately 41 to 58% in erythrocytes, 33 to 47% in plasma, 5 to 12% in granulocytes, and 4 to 9% in lymphocytes.


Side Effects

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Arpimune-O

Headache

Nausea

Vomiting

Increased hair growth

High blood pressure

Renal dysfunction

Loss of appetite

Diarrhea

Tremors


Contra Indications

an infection.

cancer or malignancy.

high cholesterol.

high amount of triglyceride in the blood.

low amount of magnesium in the blood.

high levels of potassium in the blood.

pseudotumor cerebri, a condition with high fluid pressure in the brain.

high blood pressure.


Pregnancy Related Information

Arpimune-O 100mg Capsule may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.


Product And Alcohol Interaction

Consuming alcohol with Arpimune-O 100mg Capsule does not cause any harmful side effects.


Breast Feeding Related Information

Arpimune-O 100mg Capsule is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.


Indications

Sandimmune (cyclosporine) is indicated for the prophylaxis of organ rejection in kidney, liver, and heart allogeneic transplants. It is always to be used with adrenal corticosteroids. The drug may also be used in the treatment of chronic rejection in patients previously treated with other immunosuppressive agents.


Interactions

Antibiotics. Taking cyclosporine with certain antibiotics may lead to an increased risk of kidney damage. ...

Nonsteroidal anti-inflammatory drugs (NSAIDs) ...

Antifungals. ...

Acid reflux drugs. ...

Birth control drugs. ...

Immunity-suppressing drug. ...

High cholesterol drugs. ...

Blood pressure drugs.


Typical Dosage

Arpimune-O 100mg Capsule is to be taken with food.


Storage Requirements

Store below 30°C


Effects Of Missed Dosage

If you miss a dose of Arpimune-O 100mg Capsule, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.


Effects Of Overdose

Consult a doctor before taking any medicines.


Expert Advice

Arpimune-O 100mg Capsule is used to prevent organ rejection in transplant patients.

It is also used to treat arthritis and immune disorders of the eyes, lungs, muscles, skin, nerves, and blood vessels.

It may take 3 to 4 months for the medication to work. Keep taking it as prescribed.

Your doctor may get regular blood tests done to check the levels of blood cells in your blood. Inform your doctor if you experience unexplained bruising or bleeding, sore throat, mouth ulcers, fever or general illness.

Your doctor may monitor your kidney function regularly. Drink 8 to 10 glasses of water per day to help with your kidney function.

Do not stop taking Arpimune-O 100mg Capsule without talking to your doctor first.


How To Use

Take this medicine in the dose and duration as advised by your doctor. Arpimune-O 100mg Capsule is to be taken with food.


FAQs

Q. Is Arpimune-O 100mg Capsule a steroid?

No, Arpimune-O 100mg Capsule is not a steroid. It belongs to a group of medicines known as immunosuppressive agents. It decreases the action of the body’s immune system.

Q. Can Arpimune-O 100mg Capsule cause weight gain?

Arpimune-O 100mg Capsule may either cause an increase or decrease in weight. However, the changes in weight are uncommon side effects of this medicine. Consult your doctor if these side effects worry you.

Q. Does Arpimune-O 100mg Capsule cause hair growth?

Yes, the use of Arpimune-O 100mg Capsule may cause abnormal hair growth (hypertrichosis) as a common side effect of Arpimune-O 100mg Capsule, though it does not affect everyone.

Q. Does Arpimune-O 100mg Capsule cause fatigue?

Yes, Arpimune-O 100mg Capsule may cause fatigue as a common side effect. However, fatigue could also be due to an underlying disease. Discuss with your doctor if this side effect worries you.