Manufacturer: Glenmark Pharmaceuticals Ltd
Salt Composition : Ibuprofen(400mg), Paracetamol(325mg), Chlorzoxazone(250mg)
Strip of 10 Tablet
(Inclusive of all taxes)
Artiflex Plus 400mg/325mg/250mg Tablet may be prescribed alone or in combination with another medicine. It should be taken with food. This will prevent you from getting an upset stomach. You should take it strictly as advised by your doctor. Do not take more or use it for longer duration than recommended by your doctor.
Using this medicine may cause common side effects such as nausea, indigestion, stomach pain, weakness, dizziness, and sleepiness. If you experienced any such side effects that do not resolve with time or get worse, you should let your doctor know. Your doctor may help with ways to reduce or prevent them.
The medicine may not be suitable for everybody. Before taking it, let your doctor know if you have any medical conditions or disorders. Let your doctor also know all the other medicines you are taking. Pregnant and breastfeeding mothers should consult their doctors first before using the medicine.
Ibuprofen+Paracetamol+Chlorzoxazone is a combination of three medicines: Ibuprofen, Paracetamol and Chlorzoxazone. This medication helps in relieving muscle pain. It works by relaxing the muscles by acting upon the central nervous system and lowering chemical substance in the body which causes muscle pain.
Pharmacokinetics. After oral administration, peak serum concentration is reached after 1–2 hours, and up to 99% of the drug is bound to plasma proteins. The majority of ibuprofen is metabolized and eliminated within 24 hours in the urine; however, 1% of the unchanged drug is removed through biliary excretion.
It distributes rapidly and evenly throughout most tissues and fluids and has a volume of distribution of approximately 0.9L/kg. 10 to 20% of the drug is bound to red blood cells. Paracetamol is extensively metabolised (predominantly in the liver), the major metabolites being the sulphate and glucuronide conjugates.
Chlorzoxazone is rapidly metabolized in the liver and is excreted in the urine, primarily in a conjugated form as the glucuronide. Chlorzoxazone is rapidly metabolized and is excreted in the urine, primarily in a conjugated form as the glucuronide.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Artiflex Plus
Nausea
Indigestion
Stomach pain
Weakness
Dizziness
Sleepiness
Heartburn
CHLORZOXAZONE+IBUPROFEN+PARACETAMOL is known to be contra-indicated in patients allergic to painkillers (NSAIDs) or any of the components or excipients of this medicine. Its use should also be avoided in patients with history of heart failure, high blood pressure, stomach ulcer and kidney/liver disease.
Artiflex Plus 400mg/325mg/250mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
It is unsafe to consume alcohol with Artiflex Plus 400mg/325mg/250mg Tablet.
Information regarding the use of Artiflex Plus 400mg/325mg/250mg Tablet during breastfeeding is not available. Please consult your doctor.
CHLORZOXAZONE+IBUPROFEN+PARACETAMOL is used in the reduction of musculoskeletal pain and muscle spasm due to tissue injury, resolution of post surgery inflammation and oedema (swollen tissue with fluid).
Like all medicines, CHLORZOXAZONE+IBUPROFEN+PARACETAMOL may cause side effects, although not everybody gets them. Nausea, indigestion, diarrhoea, drowsiness, dizziness, heartburn, stomach pain and restlessness are a few common side effects of CHLORZOXAZONE+IBUPROFEN+PARACETAMOL.
Do not chew, crush or break it. Artiflex Plus 400mg/325mg/250mg Tablet is to be taken with food.
Store below 30°C
If you miss a dose of Artiflex Plus 400mg/325mg/250mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
You have been prescribed Artiflex Plus 400mg/325mg/250mg Tablet to get relief from pain and stiffness in the muscles.
Along with taking it, your doctor might advise you to undergo physiotherapy to get relief from pain.
You might experience nausea, ask your doctor to prescribe you an antiemetic (anti-sickness medicine) if it troubles you.
Immediately seek medical help if you experience hallucinations, sweating, shivering, fast heart rate, muscle twitching, or loss of coordination.
Inform your doctor if you have a history of seizures, heart disease, or stroke.
If you have asthma, symptoms such as wheeze or breathlessness might become worse by Artiflex Plus 400mg/325mg/250mg Tablet. If this happens to you, consult your doctor immediately.
You have been prescribed Artiflex Plus 400mg/325mg/250mg Tablet to get relief from pain and stiffness in the muscles.
Along with taking it, your doctor might advise you to undergo physiotherapy to get relief from pain.
You might experience nausea, ask your doctor to prescribe you an antiemetic (anti-sickness medicine) if it troubles you.
Immediately seek medical help if you experience hallucinations, sweating, shivering, fast heart rate, muscle twitching, or loss of coordination.
Inform your doctor if you have a history of seizures, heart disease, or stroke.
If you have asthma, symptoms such as wheeze or breathlessness might become worse by Artiflex Plus 400mg/325mg/250mg Tablet. If this happens to you, consult your doctor immediately.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Artiflex Plus 400mg/325mg/250mg Tablet is to be taken with food.
Q. What is Artiflex Plus 400mg/325mg/250mg Tablet?
Artiflex Plus 400mg/325mg/250mg Tablet is a combination of three medicines: Ibuprofen, Paracetamol and Chlorzoxazone. This medication helps in relieving muscle pain. It works by relaxing the muscles by acting upon the central nervous system and lowering chemical substance in the body which causes muscle pain.
Q. Can the Artiflex Plus 400mg/325mg/250mg Tablet be stopped when pain is relieved?
Artiflex Plus 400mg/325mg/250mg Tablet is usually used for short term and can be discontinued when the pain is relieved. However, Artiflex Plus 400mg/325mg/250mg Tablet should be continued if the doctor has advised to do so.
Q. Can the use of Artiflex Plus 400mg/325mg/250mg Tablet cause nausea and vomiting?
Yes, the use of Artiflex Plus 400mg/325mg/250mg Tablet can cause nausea and vomiting. Taking it with milk, food or with antacids can prevent nausea. Avoid taking fatty or fried foods along with this medication. In case of vomiting, drink plenty of water or other fluids by taking small frequent sips. Talk to your doctor if vomiting persists and you notice signs of dehydration, like dark colored and strong-smelling urine and a low frequency of urination. Do not take any other medicine without speaking to a doctor.
Q. Can the use of Artiflex Plus 400mg/325mg/250mg Tablet cause dizziness?
Yes, the use of Artiflex Plus 400mg/325mg/250mg Tablet can cause dizziness (feeling faint, weak, unsteady or lightheaded) in some patients. If you feel dizzy or lightheaded it is better to rest for some time and resume once you feel better.
